Results 81 to 90 of about 25,987 (206)
Novel approaches for drug development against chronic primary pain: A systematic review
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
CLINICAL CASE OF TOCILIZUMAB THERAPY IN A PATIENT WITH SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS
The article presents a case of successful application of a monoclonal antibodies drug to interleukin 6 receptors (tocilizumab) at severe systemic juvenile idiopathic arthritis with the development of secondary hemophagocytic syndrome.
E. I. Alexeeva +3 more
doaj +1 more source
ABSTRACT Introduction The accurate physical examination of musculoskeletal (MSK) health is an essential part of proactive best practice care of people with hemophilia and must be consistently monitored in clinic. In response to current MSK tool limitations, the Musculoskeletal Health Expert Working Group (MSKH EWG) of the International Prophylaxis ...
Lizabeth Teshler +16 more
wiley +1 more source
Juvenile Idiopathic Arthritis [PDF]
openaire +2 more sources
ABSTRACT Genetic factors that modulate immune regulation are increasingly recognised as contributors to the heterogeneity and clinical course of autoimmune diseases. Polymorphisms of protein tyrosine phosphatase non‐receptor type 22 (PTPN22) are associated with several autoimmune diseases.
Sonja Kvist +5 more
wiley +1 more source
Background: Juvenile idiopathic arthritis (JIA) is a chronic disease of childhood. Increased prevalence of periodontal disease and dental caries in juvenile idiopathic arthritis is due to difficulties in executing good oral hygiene.
Zainab Shallan, Nadia Aftan Al-Rawi
doaj +1 more source
This systematic review establishes disease‐specific dysregulations of human innate lymphoid cells (ILCs), demonstrating that an ILC1/ILC3 imbalance compromises mucosal barriers in inflammatory bowel disease, while activated ILC2s drive allergic airway inflammation.
Luan F. Lückmann +7 more
wiley +1 more source
The authors represent a review of modern views on abatacept usage in treatment of juvenile idiopathic arthritis emphasizing its high level of safety and possibility to use it in patients resistant to standard basic therapy and tumor necrosis factor alfa ...
L. A. Balykova +3 more
doaj +1 more source
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra +5 more
wiley +1 more source
OBJETIVO: Descrever as características da síndrome de ativação macrofágica associada a artrite idiopática juvenil. DESCRIÇÃO DOS CASOS: Foram analisados retrospectivamente os prontuários de 462 pacientes com artrite idiopática juvenil. Destes, sete (1,5%)
Clovis Artur A. Silva +6 more
doaj +1 more source

