Results 81 to 90 of about 25,987 (206)

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

CLINICAL CASE OF TOCILIZUMAB THERAPY IN A PATIENT WITH SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS

open access: yesПедиатрическая фармакология, 2013
The article presents a case of successful application of a monoclonal antibodies drug to interleukin 6 receptors (tocilizumab) at severe systemic juvenile idiopathic arthritis with the development of secondary hemophagocytic syndrome.
E. I. Alexeeva   +3 more
doaj   +1 more source

Healthcare Professional Identified Priorities for a New Musculoskeletal Examination Scoring System for People With Hemophilia—an International Consensus

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction The accurate physical examination of musculoskeletal (MSK) health is an essential part of proactive best practice care of people with hemophilia and must be consistently monitored in clinic. In response to current MSK tool limitations, the Musculoskeletal Health Expert Working Group (MSKH EWG) of the International Prophylaxis ...
Lizabeth Teshler   +16 more
wiley   +1 more source

Juvenile Idiopathic Arthritis [PDF]

open access: yesDeutsches Ärzteblatt international, 2020
openaire   +2 more sources

The Effect of PTPN22 Polymorphism on Juvenile Idiopathic Arthritis Subtypes and Disease Activity in a Finnish Study Population

open access: yesInternational Journal of Immunogenetics, EarlyView.
ABSTRACT Genetic factors that modulate immune regulation are increasingly recognised as contributors to the heterogeneity and clinical course of autoimmune diseases. Polymorphisms of protein tyrosine phosphatase non‐receptor type 22 (PTPN22) are associated with several autoimmune diseases.
Sonja Kvist   +5 more
wiley   +1 more source

Oral Health Status among Group of Patients with Juvenile Idiopathic Arthritis According to Duration of Illness and Age Group in Iraq

open access: yesJournal of Baghdad College of Dentistry, 2016
Background: Juvenile idiopathic arthritis (JIA) is a chronic disease of childhood. Increased prevalence of periodontal disease and dental caries in juvenile idiopathic arthritis is due to difficulties in executing good oral hygiene.
Zainab Shallan, Nadia Aftan Al-Rawi
doaj   +1 more source

The Role of Innate Lymphoid Cells in Autoimmune, Allergic and Infectious Diseases: A Systematic Review

open access: yesImmunology, EarlyView.
This systematic review establishes disease‐specific dysregulations of human innate lymphoid cells (ILCs), demonstrating that an ILC1/ILC3 imbalance compromises mucosal barriers in inflammatory bowel disease, while activated ILC2s drive allergic airway inflammation.
Luan F. Lückmann   +7 more
wiley   +1 more source

ABATACEPT IN TREATMENT OF JUVENILE IDIOPATHIC ARTHRITIS: INTERNATIONAL DATA AND EXPERIENCE OF USAGE IN THE REPUBLIC OF MORDOVIA

open access: yesВопросы современной педиатрии, 2014
The authors represent a review of modern views on abatacept usage in treatment of juvenile idiopathic arthritis emphasizing its high level of safety and possibility to use it in patients resistant to standard basic therapy and tumor necrosis factor alfa ...
L. A. Balykova   +3 more
doaj   +1 more source

Management of Non‐Plaque‐Induced Gingival Conditions: A Systematic Review—Part 2: Inflammatory and Immune Conditions; Neoplasms; and Gingival Pigmentation

open access: yesJournal of Clinical Periodontology, EarlyView.
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra   +5 more
wiley   +1 more source

Síndrome de ativação macrofágica associada com artrite idiopática juvenil sistêmica Macrophage activation syndrome associated with systemic juvenile idiopathic arthritis

open access: yesJornal de Pediatria, 2004
OBJETIVO: Descrever as características da síndrome de ativação macrofágica associada a artrite idiopática juvenil. DESCRIÇÃO DOS CASOS: Foram analisados retrospectivamente os prontuários de 462 pacientes com artrite idiopática juvenil. Destes, sete (1,5%)
Clovis Artur A. Silva   +6 more
doaj   +1 more source

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