Results 161 to 170 of about 3,332 (178)

Juvenile localized scleroderma: Is it a benign disease?

Revista Colombiana de Reumatología (English Edition), 2017
Abstract Introduction Juvenile localized scleroderma is a polymorphic disease. It is more prevalent in girls and has a significant morbidity. Extra-cutaneous involvement is common, and polyautoimmunity can reach 7%. The clinical characteristics of this disease in Colombian patients are currently unknown.
Christine Arango, Clara Malagón, María del Pilar Gómez, Catalina Mosquera, Ricardo Yépez, Tatiana González, Camilo Vargas   +6 more
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Juvenile Localized and Systemic Scleroderma

2016
Juvenile localized scleroderma and juvenile systemic sclerosis (jSSc) are sclerotic disorders which differ greatly in their extent of involvement and prognosis. Juvenile localized scleroderma, also called morphea, involves the skin and subcutaneous tissues. It occurs in 4.7–20 per 100,000 children and is ten times more frequent than jSSc. Lesions range
Lauren V. Graham, Amy S. Paller, Ivan Foeldvari   +2 more
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OP0292 Therapeutic Strategies for Juvenile Localized Scleroderma

Annals of the Rheumatic Diseases, 2015
Background Juvenile localized scleroderma (JLS) is a chronic inflammatory fibrosing disorder with numerous disease subtypes, results in deep tissue atrophy, limited functional capacity. Treatment of jLS is still contraversal, ranges from topical skin management to immunosuppressive therapy (IST).
M. Osminina, N. Geppe, O. Spitonkova, J. Kostina, E. Afonina, G. Tougarinova   +5 more
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New Developments in Juvenile Systemic and Localized Scleroderma

Rheumatic Disease Clinics of North America, 2013
Juvenile localized scleroderma (jLS) and juvenile systemic sclerosis (jSS) are both orphan diseases, with jLS around 10 times more frequent than jSS. In recent years the time gap between the appearance of symptoms and diagnosis has become significantly shorter.
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Sarcopenia in juvenile localized scleroderma: new insights on deep involvement

European Radiology, 2020
Juvenile localized scleroderma (JLS) is a rare chronic autoimmune disease which can also affect bones and muscles. Nevertheless, muscle loss was not previously investigated in patients with JLS. Thus, the aim of this study was to retrospectively evaluate deep involvement and assess and quantify sarcopenia in JLS patients using magnetic resonance ...
Silvia Karem Janet Flores Quispe, Annachiara Cavaliere, Michael Weber, Roberto Stramare, Monica Zuliani, Emilio Quaia, Francesco Zulian, Chiara Giraudo   +7 more
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Juvenile Localized Scleroderma

2011
Juvenile localized scleroderma (JLS), known as morphea, comprises a group of conditions which involve essentially the skin and subcutaneous tissues. They have various features and range from very small plaques to extensive fibrotic lesions which may cause significant functional changes and cosmetic deformities.
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Juvenile Localized Scleroderma

Rheumatic Disease Clinics of North America, 2021
Natalia Vasquez-Canizares, Suzanne C. Li
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[Juvenile localized scleroderma].

Dermatologie (Heidelberg, Germany)
Juvenile scleroderma, often referred to as juvenile localized scleroderma or "morphea", is a rare inflammatory disease of the skin and skin-related structures, accompanied by local sclerosis and tissue fibrosis. Depending on the clinical manifestation, four different subtypes can be defined: limited, generalized, linear, and mixed.
Timmy, Strauss, Claudia, Günther, Normi, Brück   +2 more
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[Clinical characteristics of patients with juvenile localized scleroderma].

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2011
To investigate the clinical characteristics of juvenile localized scleroderma (JLS).The clinical data of 100 outpatients with JLS who were admitted to PUMC Hospital from 2000 to 2008 were retrospectively analyzed.Of a total of 100 cases, 51 (51%) were confirmed as linear scleroderma, 26 (26%) as plaque morphea, 26 (26%) as deep morphea, 12 (12%) as ...
Qiu-Ning, Sun, Wei, Du, Bin, Hu, Pai, Liu, Xie, Yuan   +4 more
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Challenges and complications in juvenile localized scleroderma: A practical approach

Best Practice & Research Clinical Rheumatology
Juvenile localized scleroderma is characterised by inflammation which drives fibrosis in skin and soft tissues. The more severe subtypes of localized scleroderma such as linear and craniofacial are more common in children. Additionally, extracutaneous involvement is seen in half of all children and is associated with poorer treatment outcomes and ...
Clare E. Pain, Kathryn S. Torok
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