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Juvenile Localized and Systemic Scleroderma
2016Juvenile localized scleroderma and juvenile systemic sclerosis (jSSc) are sclerotic disorders which differ greatly in their extent of involvement and prognosis. Juvenile localized scleroderma, also called morphea, involves the skin and subcutaneous tissues. It occurs in 4.7–20 per 100,000 children and is ten times more frequent than jSSc. Lesions range
Lauren V. Graham +2 more
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OP0292 Therapeutic Strategies for Juvenile Localized Scleroderma
Annals of the Rheumatic Diseases, 2015Background Juvenile localized scleroderma (JLS) is a chronic inflammatory fibrosing disorder with numerous disease subtypes, results in deep tissue atrophy, limited functional capacity. Treatment of jLS is still contraversal, ranges from topical skin management to immunosuppressive therapy (IST).
M. Osminina +5 more
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Sarcopenia in juvenile localized scleroderma: new insights on deep involvement
European Radiology, 2020Juvenile localized scleroderma (JLS) is a rare chronic autoimmune disease which can also affect bones and muscles. Nevertheless, muscle loss was not previously investigated in patients with JLS. Thus, the aim of this study was to retrospectively evaluate deep involvement and assess and quantify sarcopenia in JLS patients using magnetic resonance ...
Silvia Karem Janet Flores Quispe +7 more
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Juvenile Localized Scleroderma
2011Juvenile localized scleroderma (JLS), known as morphea, comprises a group of conditions which involve essentially the skin and subcutaneous tissues. They have various features and range from very small plaques to extensive fibrotic lesions which may cause significant functional changes and cosmetic deformities.
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Juvenile Localized Scleroderma
Rheumatic Disease Clinics of North America, 2021Natalia Vasquez-Canizares, Suzanne C. Li
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[Juvenile localized scleroderma].
Dermatologie (Heidelberg, Germany)Juvenile scleroderma, often referred to as juvenile localized scleroderma or "morphea", is a rare inflammatory disease of the skin and skin-related structures, accompanied by local sclerosis and tissue fibrosis. Depending on the clinical manifestation, four different subtypes can be defined: limited, generalized, linear, and mixed.
Timmy, Strauss +2 more
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[Clinical characteristics of patients with juvenile localized scleroderma].
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2011To investigate the clinical characteristics of juvenile localized scleroderma (JLS).The clinical data of 100 outpatients with JLS who were admitted to PUMC Hospital from 2000 to 2008 were retrospectively analyzed.Of a total of 100 cases, 51 (51%) were confirmed as linear scleroderma, 26 (26%) as plaque morphea, 26 (26%) as deep morphea, 12 (12%) as ...
Qiu-Ning, Sun +4 more
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SP0206 Juvenile Localized Scleroderma: Assessing Disease Activity and Treatment
Annals of the Rheumatic Diseases, 2015During the recent years various methods for the clinical monitoring of localized scleroderma have been developed but none has been already validated in large cohort of patients. Semi quantitative scoring methods, such as the Localized Scleroderma Severity Index (LoSSI), have been proposed.
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SP0205 Juvenile Localized Scleroderma: Clinical Aspects and Differential Diagnosis
Annals of the Rheumatic Diseases, 2015Juvenile localised scleroderma (jLSc), also known as morphea, is a rare disorder that is characterized by localized areas of hardening of the skin and subcutaneous tissues, often resulting in damage that includes atrophy, pigment change, growth disturbance and cosmetic challenges.
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Juvenile localized scleroderma: A disease with significant morbidity
Journal of the European Academy of Dermatology and Venereology, 2023openaire +2 more sources