Results 21 to 30 of about 3,332 (178)

Development of consensus treatment plans for juvenile localized scleroderma: a roadmap toward comparative effectiveness studies in juvenile localized scleroderma. [PDF]

Arthritis Care Res (Hoboken), 2012
AbstractObjectiveJuvenile localized scleroderma (LS) is a chronic inflammatory skin disorder associated with substantial morbidity and disability. Although a wide range of therapeutic strategies has been reported in the literature, a lack of agreement on treatment specifics and accepted methods for clinical assessment has made it difficult to compare ...
Li SC, Torok KS, Pope E, Dedeoglu F, Hong S, Jacobe HT, Rabinovich CE, Laxer RM, Higgins GC, Ferguson PJ, Lasky A, Baszis K, Becker M, Campillo S, Cartwright V, Cidon M, Inman CJ, Jerath R, O'Neil KM, Vora S, Zeft A, Wallace CA, Ilowite NT, Fuhlbrigge RC, Childhood Arthritis and Rheumatology Research Alliance (CARRA) Localized Scleroderma Workgroup.   +24 more
europepmc   +4 more sources

Juvenile Localized Scleroderma from the Perspective of Pediatric Rheumatologist. Aspects of Diagnostics

Вопросы современной педиатрии, 2020
The localized scleroderma (morphea) is the clinical option of the juvenile scleroderma, the third in prevalence rheumatic condition in pediatrics. The article summarizes all the data on the classification, diagnostics, and differential diagnosis of ...
Rinat K. Raupov, Artur I. Imelbaev, Mikhail M. Kostik   +2 more
doaj   +3 more sources

Esophageal abnormalities in juvenile localized scleroderma: is it associated with other extracutaneous manifestations?

Revista Brasileira de Reumatologia, 2016
Objective: To assess esophageal involvement (EI) in juvenile localized scleroderma (JLS) population and the possible association between this gastrointestinal manifestation and demographic data, clinical features, laboratory exams, treatments and ...
Clarissa C.M. Valões, Glaucia V. Novak, Juliana B. Brunelli, Katia T. Kozu, Ricardo K. Toma, Clovis A. Silva   +5 more
doaj   +2 more sources

Developing comparative effectiveness studies for a rare, understudied pediatric disease: lessons learned from the CARRA juvenile localized scleroderma consensus treatment plan pilot study [PDF]

Pediatric Rheumatology Online Journal, 2019
Background We designed and initiated a pilot comparative effectiveness study for juvenile localized scleroderma (jLS), for which there is limited evidence on best therapy.
Suzanne C. Li, Robert C. Fuhlbrigge, Ronald M. Laxer, Elena Pope, Maria F. Ibarra, Katie Stewart, Thomas Mason, Mara L. Becker, Sandy Hong, Fatma Dedeoglu, Kathryn S. Torok, C. Egla Rabinovich, Polly J. Ferguson, Marilynn Punaro, Brian M. Feldman, Tracy Andrews, Gloria C. Higgins, For the CARRA Registry Investigators   +17 more
doaj   +2 more sources

United Kingdom survey of current management of juvenile localized scleroderma [PDF]

Rheumatology, 2014
Juvenile localized scleroderma (JLS) is a rare condition that is often difficult to assess and for which a variety of monitoring tools have been described. We aimed to describe how monitoring tools are used and perceived by clinicians in the UK, to ascertain treatments used for JLS and to provide a description of transition arrangements to adult care ...
DP Hawley, Clare Pain, Eileen Baildam, Ruth Murphy, Aileen Taylor, HE Foster   +5 more
openalex   +4 more sources

Revealing Microvascular Involvement in Pediatric Localized Scleroderma Through Nailfold Capillaroscopy [PDF]

Children
Background/Objectives: Juvenile localized scleroderma (jLoS) is a chronic inflammatory disorder with skin and subcutaneous tissue involvement. Microvascular alterations are thought to contribute to its pathogenesis.
Sema Nur Taşkın, Şeyda Doğantan, Esra Esen, Sümeyra Özdemir Çiçek, Ayşenur Paç Kısaarslan, Muammer Hakan Poyrazoğlu   +5 more
doaj   +2 more sources

New Challenging Systemic Therapies for Juvenile Scleroderma: A Comprehensive Review [PDF]

Pharmaceuticals
Background: Juvenile scleroderma (JS) comprises a group of rare chronic autoimmune and fibrosing disorders in children, primarily presenting as juvenile localized scleroderma (jLS) or juvenile systemic sclerosis (jSS). While jLS predominantly affects the
Chiara Sassetti, Claudia Borrelli, Martha Mazuy, Cristina Guerriero, Donato Rigante, Susanna Esposito   +5 more
doaj   +2 more sources

DNA methylation patterns in juvenile systemic sclerosis and localized scleroderma

Clinical Immunology, 2021
Scleroderma refers to a group of chronic fibrotic immune-mediated diseases of unknown etiology. Characterizing epigenetic changes in childhood-onset scleroderma, systemic sclerosis or localized scleroderma, has not been previously performed. The aim of this study was to assess DNA methylation differences and similarities between juvenile systemic ...
Patrick Coit, Kaila L. Schollaert, Emily Mirizio, Kathryn S. Torok, Amr H. Sawalha   +4 more
openalex   +4 more sources

Juvenile Localized Scleroderma [PDF]

, 2020
National Cancer Institute
openalex   +2 more sources

Juvenile localized scleroderma: beyond our eyes can see

Residência Pediátrica
INTRODUÇÃO: Esclerodermia localizada juvenil (ELJ) é a forma mais comum de esclerodermia na infância e representa um grupo de entidades clínicas distintas, com espessamento de epiderme, derme e tecido subcutâneo adjacente. Há poucos dados descritos na população brasileira.
A. V. C. Almeida, Carlos Rabelo Júnior, Marco Silva, Francisco Pereira Neto, José Reginaldo Feijão Parente, Miria Cavalcante, Natália Gomes Iannini   +6 more
openalex   +2 more sources