Results 61 to 70 of about 9,585 (206)

Pansclerotic Morphea with Features of Eosinophilic Fasciitis: Distinct Entities or Part of a Continuum? [PDF]

, 2014
Scleroderma is a highly complex disorder in its clinical manifestations and pathogenesis. It has a wide range of clinical manifestations due to varying degrees of vasculopathy, autoimmunity, altered endothelium function, and abnormal fibrosis.
Canty, Kristi, Hoeltzel, Mark F., Odhav, Ashika   +2 more
core   +1 more source

POS1301 OCCURRENCE OF ARTHRITIS IS IN 37% OF THE PATIENTS WITHOUT OVERLYING SKIN INVOLVEMENT IN JUVENILE LOCALIZED SCLERODERMA. SUMMARY OF THE EXTRACUTANEOUS INVOLVEMENT IN A MONOCENTRIC COHORT.

Annals of the Rheumatic Diseases, 2022
Localized scleroderma in childhood (locSSc) occurs with a prevalence of 3.2 to 3.6 per 10 000 children1. There are not many publications assessing in detail the extracutaneous manifestations (EM) of locSSc.
A. Petersen, I. Foeldvari
semanticscholar   +1 more source

Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis [PDF]

, 2014
In this study, 1,833 systemic sclerosis (SSc) cases and 3,466 controls were genotyped with the Immunochip array. Classical alleles, amino acid residues, and SNPs across the human leukocyte antigen (HLA) region were imputed and tested.
, Airó, Paolo, Alarcón-Riquelme, Marta, AlKassab, Firas, Arnett, Frank C., Assassi, Shervin, Baron, Murray, Beretta, Lorenzo, Bossini-Castillo, Lara, Broen, Jasper, Brown, Matthew, Carmona, Francisco David, Carreira, Patricia, Castellví, Iván, Chen, Wei V., Denton, Christopher, Distler, Jörg H.W., Docherty, Peter, Fessler, Barri J., Fonseca, Carmen, Frech, Tracy M., Furst, Daniel E., González-Gay, Miguel Ángel, Gorlova, Olga, Gregersen, Peter K., Guerra, Sandra, Herrick, Ariane, Hesselstrand, Roger, Hinchcliff, Monique E., Hudson, Marie, Hummers, Laura K., Hunzelmann, Nicolas, Jones, Henry Niall, Kaminska, Elzbieta, Khalidi, Nader, Khanna, Dinesh, Koeleman, Bobby P., Kreuter, Alexander, Lafyatis, Robert A., Lee, Annette T., Lunardi, Claudio, López-Isac, Elena, Markland, Janet, Martin, Javier, Martin, José Ezequiel, Mayes, Maureen D., Molitor, Jerry A., Nordin, Annika, Ochoa, Eguzkine, Padyukov, Leonid, Phillips, Kristin, Pope, Janet E., Radstake, Timothy R.D.J., Reveille, John D., Riemekasten, Gabriela, Robinson, David, Schiopu, Elena, Schuerwegh, Annemie J., Segal, Barbara M., Shiels, Paul, Silver, Richard M., Simeón, Carmen Pilar, Simms, Robert W., Steen, Virginia D., Tan, Filemon K., Teruel, María, van Laar, Jacob M., Varga, John, Voskuyl, Alexandre E., Wigley, Fredrick M., Wijmenga, Cisca, Witte, Torsten, Worthington, Jane, Ying, Jun, Zhernakova, Alexandra, Zhou, Xiaodong   +75 more
core   +1 more source

Ultrasonography, MRI and classic radiography of skin and MSK involvement in juvenile scleroderma

Journal of Ultrasonography, 2020
Scleroderma is a rare, autoimmune, chronic condition that affects the connective tissue by excessive collagen production. If diagnosed before the age of 16, it is referred to as juvenile scleroderma.
Idzior Marta, Sotniczuk Maria, Michalski Emil, Gietka Piotr, Sudoł-Szopińska Iwona   +4 more
doaj   +1 more source

Factors associated with adherence to treatment in children and adolescents with chronic rheumatic diseases [PDF]

, 2012
OBJECTIVE: There are several factors that contribute to poor adherence to treatment in children and adolescents with chronic rheumatic diseases, worsening their quality of life and prognosis.
Barbosa, Cassia Maria Passarelli Lupoli, Bugni, Vanessa Miotto, Hilário, Maria Odete Esteves, Len, Claudio Arnaldo, Okamoto, Karine Yoshiye Kajiyama, Ozaki, Luciana da Silva, Terreri, Maria Teresa Ramos Ascensão   +6 more
core   +3 more sources

Localized scleroderma in a newborn (case report) [PDF]

РМЖ. Мать и дитя, 2022
N.I. Akhmina1, P.S. Utkin2, M.P. Shalatonin3, Zh.L. Chabaidze1, A.A. Dement’ev1, A.L. Zaplatnikov1 1Russian Medical Academy of Continuous Professional Education, Moscow,   Russian Federation 2Children’s Infectious Clinical Hospital
N.I. Akhmina, P.S. Utkin, M.P. Shalatonin, Zh.L. Chabaidze, A.A. Dementiev, A.L. Zaplatnikov   +5 more
doaj  

Selective deletion of PPARβ/δ in fibroblasts causes dermal fibrosis by attenuated LRG1 expression. [PDF]

, 2018
Connective tissue diseases of the skin are characterized by excessive collagen deposition in the skin and internal organs. Fibroblasts play a pivotal role in the clinical presentation of these conditions.
Chan, JSK, Chen, J.P., Chiba, S., Koh, NJN, Ng, X.R., Pal, M., Phua, T., Sng, M.K., Tan, C.K., Tan, EHP, Tan, N.S., Teo, Z., Tnay, Y.L., Tong, BMK, Wahli, W., Wang, X., Wee, JWK, Zhu, P.   +17 more
core   +3 more sources

Clinical and therapeutic course in head variants of linear morphea in adults: a retrospective review. [PDF]

, 2022
Parry Romberg Syndrome (PRS) and en coup de sabre (ECDS) are head variants of linear morphea with functional and structural implications. This study describes the clinical course, autoimmune co-morbidities, complications, and treatment of adults with PRS/
Fan, Winnie, Gandelman, Jocelyn, Haemel, Anna, Jacobson, Rebecca, Obiakor, Bianca   +4 more
core   +1 more source

Systemic sclerosis : state of the art on clinical practice guidelines [PDF]

, 2018
Systemic sclerosis (SSc) is an orphan disease characterised by autoimmunity, fibrosis of the skin and internal organs, and vasculopathy. SSc may be associated with high morbidity and mortality.
Airo, Paolo, Alexander, Tobias, Allanore, Yannick, Bombardieri, Stefano, Bruni, Cosimo, Burmester, Gerd, Codullo, Veronica, Cutolo, Maurizio, Dalm, Virgil, De Vries-Bouwstra, Jeska, Della Rossa, Alessandra, Distler, Oliver, Eurico, Fonseca João, Frank, Charissa, Galetti, Ilaria, Hachulla, Eric, Houssiau, Frederic, Launay, David, Lepri, Gemma, Mathian, Alexis, Matucci-Cerinic, Marco, Mosca, Marta, Mouthon, Luc, Mueller-Ladner, Ulf, Ruaro, Barbara, Schneider, Matthias, Scirè, Carlo Alberto, Smith, Vanessa, Sulli, Alberto, Talarico, Rosaria, Tincani, Angela, Van den Hoogen, Frank, van Laar, Jacob M, Van Vollenhoven, Ronald, Vandecasteele, Els, Vanhaecke, Amber, Vanthuyne, Marie, Vieira, Ana, Voskuyl, Alexandre E, Zanatta, Elisabetta   +39 more
core   +4 more sources

Clinical Profile of Methotrexate-resistant Juvenile Localised Scleroderma

Acta Dermato-Venereologica, 2019
Methotrexate has demonstrated its efficiency for the treatment of juvenile localized scleroderma but some patients may be resistant. The aim of our study was to define the profile of such patients.
Juliette Hardy, Franck Boralevi, Stéphanie Mallet, Natalia Cabrera, Alexandre Belot, Alice Phan, Sébastien Barbarot, Audrey Duriez-Lasek, Christine Chiaverini, Thomas Hubiche, Emmanuel Mahé, Edouard Bégon, Emmanuelle Bourrat, Olivia Boccara, Hélène Aubert, Martine Grall Lerosey, Catherine Droitcourt, Maryam Piram, Juliette Mazereeuw-Hautier, Research Group of the French Society of Paediatric Dermatology (SDFP in French)   +19 more
doaj   +1 more source