Results 61 to 70 of about 3,332 (178)

A Rare Case of Juvenile Systemic Sclerosis: Clinical Challenges and Management

Annals of Rheumatology and Autoimmunity
Scleroderma is “skleros” sclerosing or hardening of the “derma” skin. It includes both systemic and localized scleroderma (LS). Mostly, juvenile LS affects the skin, whereas juvenile systemic sclerosis (SSc) involves multiple organ systems.
Areej Bano, Shalini Verma, Shrish Bhatnagar   +2 more
doaj   +1 more source

Periodontitis and Periodontal Conditions in Systemically Healthy Children and Adolescents

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Objective To answer the PICoS question ‘in systemically healthy children and adolescents (Population), what are the main features of periodontitis, necrotising periodontal diseases (NPD) and other periodontal conditions (periodontal abscesses, endo‐periodontal lesions, traumatic occlusal forces, prosthesis‐ and tooth‐related factors ...
Inbar Eshkol‐Yogev, Nagore Ambrosio, Cheryl Somani, Elena Figuero, Lior Shapira, Janet Davies   +5 more
wiley   +1 more source

Identifying Key Questions and Challenges in Microchimerism Biology

Advanced Science, Volume 12, Issue 48, December 29, 2025.
This study identifies key unanswered questions about microchimerism, the presence of cells from one individual living in another. Experts highlight how these cells may affect health, pregnancy, and disease. This study outlines research priorities and challenges in detecting and studying these rare microchimeric cells, aiming to guide future discoveries
Kristine J. Chua, Rachel C. Quilang, Katja Sallinger, Christina Athena Aktipis, Petra Arck, Diana W. Bianchi, Hyun‐Dong Chang, Henderson J. Cleaves II, Michael Eikmans, Heidi E. S. Fjeldstad, David Haig, Whitney E. Harrington, William Horsnell, Daniel P. Jacobsen, Mads Kamper‐Jørgensen, Sami B. Kanaan, Kiarash Khosrotehrani, Nathalie C. Lambert, Jane Lee Nelson, Maria B. Olsen, Tiffany D. Pan, Jelmer R. Prins, Frank A. Schildberg, Anne Cathrine Staff, Anders Ståhlberg, Ina A. Stelzer, Christopher Urbschat, Sing Sing Way, Melissa A. Wilson, Jody Ye, Thomas Kroneis, Amy M. Boddy   +31 more
wiley   +1 more source

How I explore ... the skin functional involvement in scleroderma [PDF]

, 2013
peer reviewedScleroderma refers to distinct clinical presentations sharing in common a sclerotic process most often clinically obvious on the skin. The involvement possibly affects the skin alone in morphea or in combination with internal lesions in ...
Andre, B., De Roover, C., Delvenne, Philippe, Franchimont, Claudine, Hermanns-Lê, Trinh, PIERARD, Gérald, Renwart, L.   +6 more
core  

PRMT1 in Health and Disease: Emerging Perspectives From Molecular Mechanisms to Therapeutic Strategies

MedComm, Volume 6, Issue 12, December 2025.
Protein arginine methyltransferase 1 (PRMT1) is a pivotal enzyme that catalyzes the asymmetric dimethylation of arginine residues, thereby functioning as a critical epigenetic regulator of diverse biological processes such as gene expression, RNA splicing, and DNA repair.
Yanqun Luo, Ying Gao, Xiaoliang Deng, Lei Wang, Tao Wu   +4 more
wiley   +1 more source

Optimal management strategies for paediatric morphea – insights from a case series

Pediatria Polska
Juvenile localized scleroderma, or morphea, is a rare chronic inflammatory disease primarily affecting the skin and subcutaneous tissue. Treatment options for paediatric cases are diverse, with a lack of standardised guidelines.
Kinga Łagosz, Natalia Bień, Justyna Ceryn, Paulina Barsińska, Dorota Sobolewska-Sztychny, Joanna Narbutt, Aleksandra Lesiak   +6 more
doaj   +1 more source

Scalable Collaborative Infrastructure for a Learning Healthcare System (SCILHS): Architecture [PDF]

, 2014
We describe the architecture of the Patient Centered Outcomes Research Institute (PCORI) funded Scalable Collaborative Infrastructure for a Learning Healthcare System (SCILHS, http://www.SCILHS.org) clinical data research network, which leverages the $48
Adams, William G, Bernstam, Elmer, Bickel, Jonathan, Ge, Yaorong, Hripcsak, George, Klann, Jeffrey G, Kohane, Isaac S, Mandel, Joshua, Mandl, Kenneth D, Marsolo, Keith, McFadden, Douglas, Murphy, Shawn N, Natter, Marc, Ofili, Elizabeth, Perkins, James, Quarshie, Alexander, Schneeweiss, Sebastian, Showalter, John, Weber, Griffin M, Weiler, Sarah, Zhou, Xiaobo   +20 more
core   +2 more sources

Progressive Soft Tissue Swelling in a Pediatric Patient Leading to the Diagnosis of Fibrodysplasia Ossificans Progressiva: A Case Report

Pediatric Dermatology, Volume 42, Issue 6, Page 1252-1254, November/December 2025.
ABSTRACT Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disorder characterized by progressive heterotopic ossification (HO) and congenital malformation of the great toes. This case describes a 5‐year‐old Caucasian girl who initially presented with painless neck and back swelling as well as severe limitation of movement in the neck and ...
Orhan Yilmaz, Loretta Fiorillo
wiley   +1 more source

Pediatric connective tissue diseases:Looking through the skin and beyond [PDF]

, 2022
In this thesis new disease biomarkers for chronic autoimmune diseases (‘connective tissue diseases’ (CTD)) such as childhood-onset Systemic Lupus Erythematosus (cSLE), Mixed Connective Tissue Disease (MCTD) and Localized Scleroderma (LS) are discussed ...
Schonenberg-Meinema, D.
core   +4 more sources

The Videofluorographic Swallowing Study in Rheumatologic Diseases: A Comprehensive Review [PDF]

, 2017
Autoimmune connective tissue diseases are a heterogeneous group of pathologies that affect about 10% of world population with chronic evolution in 20%-80%.
Costanzo, M., Cupido, F., DI PIAZZA, A., Galia, M., Lagalla, R., LO CASTO, A., LO RE, G., Midiri, F., Midiri, M., Picone, D., Salerno, S., Salvaggi, F., Scopelliti, L., Vernuccio, F.   +13 more
core   +3 more sources