Results 91 to 100 of about 25,057 (208)
Juvenile-onset systemic lupus erythematosus in Malay children
Saudi Medical Journal, 2018 [No abstract available].
Ali S, Jawad, Wan Zuraida W A, Hamid
openaire +2 more sources
NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction
Advanced Science, Volume 13, Issue 8, 9 February 2026.NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu +15 more
wiley +1 more source
Genetic relationships between A20/TNFAIP3, chronic inflammation and autoimrnune disease [PDF]
, 2011 A20 [also known as TNFAIP3 (tumour necrosis factor a-induced protein 3)] restricts and terminates inflammatory responses through modulation of the ubiquitination status of central components in NF-kappa B (nuclear factor kappa B), IRF3 (interferon ...
Beyaert, Rudi +2 more
core +2 more sources
Advanced Science, Volume 13, Issue 7, 3 February 2026.Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An +8 more
wiley +1 more source
Macrophage Activation Syndrome: A Report of Two Cases and a Literature Review
Case Reports in Rheumatology, 2017 Macrophage activation syndrome (MAS) is a severe, potentially fatal condition that may complicate autoimmune diseases, and it belongs to hemophagocytic lymphohistiocytosis (HLH) disorders. MAS occurs in adults and children.
Asaad Alkoht +2 more
doaj +1 more source
Lupus nephritis management guidelines compared [PDF]
, 2015 In the past years, many (randomized) trials have been performed comparing the treatment strategies for lupus nephritis. In 2012, these data were incorporated in six different guidelines for treating lupus nephritis.
Bajema, IM +7 more
core +1 more source
Revista Brasileira de Reumatologia, 2016 Objective To determine whether there is an association between the profile of cognitive dysfunction and academic outcomes in patients with juvenile systemic lupus erythematosus (JSLE).
Renan Bazuco Frittoli +5 more
doaj +1 more source
Depression and anxiety and their association with healthcare utilization in pediatric lupus and mixed connective tissue disease patients: a cross-sectional study [PDF]
, 2014 Background Depression and anxiety adversely affects outcomes in systemic lupus erythematosus (SLE) and healthcare utilization is high for pediatric SLE.
Gerdes, Marsha +6 more
core +1 more source
IKAROS Associated Immunodeficiency and Thrombotic Thrombocytopenic Purpura
Pediatric Blood &Cancer, Volume 73, Issue 2, February 2026.ABSTRACT Pathogenic variants in IKZF1 (IKAROS) are linked to immunodeficiency, malignancy, and immune dysregulation. We describe a family with a rare IKZF1 variant presenting with humoral immunodeficiency and thrombotic thrombocytopenic purpura (TTP). A non‐consanguineous family was clinically monitored; clinical, immunological, and genetic data (exome
Ilia Spivak +7 more
wiley +1 more source
Macrophage Activation Syndrome as Initial Presentation of Systemic Lupus Erythematosus
Pediatrics and Neonatology, 2008 Macrophage activation syndrome (MAS) is known to be a severe and potentially life-threatening complication of rheumatic disorder, especially systemic juvenile rheumatoid arthritis.
Say-Tin Yeap +5 more
doaj +1 more source