Results 111 to 120 of about 14,773 (152)

Juvenile systemic lupus erythematosus

2016
Juvenile-onset systemic lupus erythematosus (JSLE) is similar to adult-onset SLE, but there are distinct differences in clinical features, serology, and management requirements. It is more aggressive than adult-onset SLE with frequent renal and haematological manifestations and higher mortality rates.
Claire Louise Murphy, Yiannis Ioannou, Nicola Ambrose   +2 more
openaire   +1 more source

Hepatic Manifestations in Juvenile Systemic Lupus Erythematosus

Recent Patents on Inflammation & Allergy Drug Discovery, 2014
Juvenile systemic lupus erythematosus (JSLE) is a chronic autoimmune disease characterized by multisystem involvement and diverse clinical and serological manifestations. Clinically significant hepatic disease is generally regarded as unusual in JSLE, but many studies have showed that hepatic disease may be more common in SLE than was usually thought ...
Mortada H, El-Shabrawi, Mona I, Farrag
openaire   +2 more sources

Outcome in juvenile onset systemic lupus erythematosus

Current Opinion in Rheumatology, 2005
Over the past 2 decades, there has been a marked improvement in survival among patients with juvenile-onset systemic lupus erythematosus. As a result of the increased life expectancy, children and adolescents with systemic lupus erythematosus are now faced with considerable morbidity resulting from sequelae of disease activity, side effects of ...
RAVELLI, ANGELO, RUPERTO N, MARTINI, ALBERTO   +2 more
openaire   +3 more sources

Hypophosphatemia in juvenile patients with systemic lupus erythematosus

Pediatrics International, 2003
Abstract Background : Hypophosphatemia is observed in both genetic diseases and acquired disorders, although it has never been described in systemic lupus erythematosus (SLE). The present study reports hypophosphatemia observed in patients with SLE, and investigates whether serum phosphorus (P) concentration is ...
Ikuma, Fujiwara, Eishin, Ogawa, Yoshiaki, Kondo, Toshihiro, Ohura, Kazuie, Iinuma   +4 more
openaire   +2 more sources

Irreversible blindness in juvenile systemic lupus erythematosus

Lupus, 2010
Blindness caused by severe vasculitis or uveitis is rare in juvenile systemic lupus erythematosus (JSLE) patients. In a 27-year period, 5367 patients were followed at our Paediatric Rheumatology Division and 263 (4.9%) patients had JSLE (American College of Rheumatology criteria). Of note, two (0.8%) of them had irreversible blindness.
R T, Almeida, N E, Aikawa, A M E, Sallum, A A, Jesus, L C F, Sa, C A, Silva   +5 more
openaire   +2 more sources

Autoimmune hepatitis and juvenile systemic lupus erythematosus

Lupus, 2009
Juvenile systemic lupus erythematosus (JSLE) and autoimmune hepatitis (AIH) are both autoimmune disorders that are rare in children and have a widespread clinical manifestation. A few case reports have shown a JSLE-AIH associated disorder. To our knowledge, this is the first study that simultaneously evaluated the prevalence of JSLE-AIH in a large JLSE
Deen, M. E. J., Porta, G., Fiorot, F. J., Campos, L. M. A., Sallum, A. M. E., Silva, C. A. A.   +5 more
openaire   +3 more sources

Gastrointestinal system manifestations in juvenile systemic lupus erythematosus

Clinical Rheumatology, 2017
Systemic lupus erythematosus (SLE) is an autoimmune disease which may involve gastrointestinal system (GIS). The aim of this study was to present GIS manifestations of pediatric SLE patients. The medical files of 69 children with SLE followed between January 2011 and January 2016 were reviewed.
ÖZEN, SEZA, YÜCE, AYSEL, DEMİR, HÜLYA, BİLGİNER, YELDA, Batu, EZGİ DENİZ, Gumus, ERSİN, Karhan, ASUMAN NUR, Sonmez, HAFİZE EMİNE   +7 more
openaire   +4 more sources

Validation of the systemic lupus erythematosus responder index for use in juvenile-onset systemic lupus erythematosus

Annals of the Rheumatic Diseases, 2014
This study tested the concurrent validity of the systemic lupus erythematosus responder index (SRI) in assessing improvement in juvenile-onset systemic lupus erythematosus (jSLE).The SRI considers changes in the SELENA-SLEDAI, BILAG and a 3-cm visual analogue scale of physician-rated disease activity (PGA) to determine patient improvement.
Mina R, Klein Gitelman MS, Nelson S, Eberhard BA, Higgins G, Singer NG, Onel K, Tucker L, O'Neil KM, Punaro M, Levy DM, Haines K, MARTINI, ALBERTO, Ruperto N, Lovell D, Brunner HI   +15 more
openaire   +4 more sources

Antinucleosome Antibodies in Patients with Juvenile Systemic Lupus Erythematosus

Lupus, 2006
Our objective was to evaluate the frequency of antinucleosome antibodies (anti-Ncs) in juvenile systemic lupus erythematosus (JSLE) comparing it to that observed for anti-DNA and to correlate the presence of these antibodies with clinical manifestations and disease activity.
L M A, Campos, M H B, Kiss, M A, Scheinberg, C L P, Mangueira, C A, Silva   +4 more
openaire   +2 more sources

Juvenile-onset systemic lupus erythematosus

2013
Paediatric or juvenile-onset systemic lupus erythematosus (JSLE) is a rare autoimmune condition, differing from the adult form in terms of severity, organ manifestations, and a less striking female predominance. The diagnosis relies on the adult-derived American College of Rheumatology SLE classification criteria. Genetic, autoantibody, and host immune
Louise Watson, Michael W. Beresford
openaire   +1 more source