Results 151 to 160 of about 24,285 (193)

Superoxide release in juvenile systemic lupus erythematosus

Rheumatology International, 2011
The objective of this study was to analyze the un-stimulated and stimulated release of superoxide anion (O(2) (-)) by granulocytes and monocytes in juvenile systemic lupus erythematosus (jSLE). The un-stimulated and phorbol myristate acetate (PMA, 30 nM)-induced O(2) (-)by granulocytes and monocytes were determined in six different times of incubation ...
Roberto, Marini, Antonio, Condino-Neto, Simone, Appenzeller, André M, Morcillo, Lilian T L, Costallat   +4 more
openaire   +2 more sources

Juvenile systemic lupus erythematosus

2016
Juvenile-onset systemic lupus erythematosus (JSLE) is similar to adult-onset SLE, but there are distinct differences in clinical features, serology, and management requirements. It is more aggressive than adult-onset SLE with frequent renal and haematological manifestations and higher mortality rates.
Claire Louise Murphy, Yiannis Ioannou, Nicola Ambrose   +2 more
openaire   +1 more source

Irreversible blindness in juvenile systemic lupus erythematosus

Lupus, 2010
Blindness caused by severe vasculitis or uveitis is rare in juvenile systemic lupus erythematosus (JSLE) patients. In a 27-year period, 5367 patients were followed at our Paediatric Rheumatology Division and 263 (4.9%) patients had JSLE (American College of Rheumatology criteria). Of note, two (0.8%) of them had irreversible blindness.
R T, Almeida, N E, Aikawa, A M E, Sallum, A A, Jesus, L C F, Sa, C A, Silva   +5 more
openaire   +2 more sources

Autoimmune hepatitis and juvenile systemic lupus erythematosus

Lupus, 2009
Juvenile systemic lupus erythematosus (JSLE) and autoimmune hepatitis (AIH) are both autoimmune disorders that are rare in children and have a widespread clinical manifestation. A few case reports have shown a JSLE-AIH associated disorder. To our knowledge, this is the first study that simultaneously evaluated the prevalence of JSLE-AIH in a large ...
Deen, M. E. J., Porta, G., Fiorot, F. J., Campos, L. M. A., Sallum, A. M. E., Silva, C. A. A.   +5 more
openaire   +3 more sources

Gastrointestinal system manifestations in juvenile systemic lupus erythematosus

Clinical Rheumatology, 2017
Systemic lupus erythematosus (SLE) is an autoimmune disease which may involve gastrointestinal system (GIS). The aim of this study was to present GIS manifestations of pediatric SLE patients. The medical files of 69 children with SLE followed between January 2011 and January 2016 were reviewed.
Batu, Ezgi Deniz, ÖZEN, SEZA, Gumus, Ersin, YÜCE, AYSEL, Sonmez, HAFİZE EMİNE, BİLGİNER, YELDA, Karhan, Asuman Nur, DEMİR, HÜLYA   +7 more
openaire   +3 more sources

Juvenile-onset systemic lupus erythematosus

2013
Paediatric or juvenile-onset systemic lupus erythematosus (JSLE) is a rare autoimmune condition, differing from the adult form in terms of severity, organ manifestations, and a less striking female predominance. The diagnosis relies on the adult-derived American College of Rheumatology SLE classification criteria. Genetic, autoantibody, and host immune
Louise Watson, Michael W. Beresford
openaire   +1 more source

Treatment Options for Juvenile-Onset Systemic Lupus Erythematosus

Pediatric Drugs, 2002
Systemic lupus erythematosus (SLE) is an inflammatory chronic disease characterized by the presence of activated helper T-cells that induce a B-cell response, resulting in the secretion of pathogenic autoantibodies and the formation of immune complexes.
Luis, Carreño, Francisco Javier, López-Longo, Carlos Manuel, González, Indalecio, Monteagudo   +3 more
openaire   +2 more sources

Coexistent Linear Scleroderma and Juvenile Systemic Lupus Erythematosus

Pediatric Dermatology, 2000
Abstract: We describe a girl who initially presented with linear scleroderma. Five and a half years later she developed systemic lupus erythematosus (SLE). Previous descriptions of the coexistence of linear scleroderma and SLE in childhood are reviewed.
M, Majeed, S M, Al-Mayouf, E, Al-Sabban, S, Bahabri   +3 more
openaire   +2 more sources

NEUROPSYCHIC POLYMORPHISM OF JUVENILE SYSTEMIC LUPUS ERYTHEMATOSUS

Clinical Medicine and Pharmacology, 2021
Damage to the nervous system (neurolupus) is one of the most common clinical manifestations of systemic lupus erythematosus (SLE) in childhood, and is also considered as an unfavorable prognostic criterion for the course of this disease. Neurolupus is characterized by a wide range of clinical manifestations in both children and adult patients, which is
O. Ivanova, M. Silenko, Yu. Minakova
openaire   +1 more source

Hypophosphatemia in juvenile patients with systemic lupus erythematosus

Pediatrics International, 2003
Abstract Background : Hypophosphatemia is observed in both genetic diseases and acquired disorders, although it has never been described in systemic lupus erythematosus (SLE). The present study reports hypophosphatemia observed in patients with SLE, and investigates whether serum phosphorus (P) concentration is ...
Ikuma, Fujiwara, Eishin, Ogawa, Yoshiaki, Kondo, Toshihiro, Ohura, Kazuie, Iinuma   +4 more
openaire   +2 more sources