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Autoimmune hepatitis and juvenile systemic lupus erythematosus
Lupus, 2009 Juvenile systemic lupus erythematosus (JSLE) and autoimmune hepatitis (AIH) are both autoimmune disorders that are rare in children and have a widespread clinical manifestation. A few case reports have shown a JSLE-AIH associated disorder. To our knowledge, this is the first study that simultaneously evaluated the prevalence of JSLE-AIH in a large JLSE
Deen, M. E. J. +5 more
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Cardio-pulmonary involvement in juvenile systemic lupus erythematosus
Lupus, 2005Cardio-pulmonary manifestations of systemic lupus erythematosus (SLE) are well recognized in adults. We report the occurrence of clinically significant cardio-pulmonary disease in a cohort of predominantly Caucasian children with SLE. All children with SLE attending the Royal Liverpool Children’s NHS Trust between 1995 and 2003 were reviewed.
Michael W Beresford +2 more
exaly +3 more sources
Low disease activity state in juvenile-onset systemic lupus erythematosus
Lupus, 2021 Objectives To determine the rate of achieving The Lupus Low Disease Activity State (LLDAS) in children with systemic lupus erythematosus (SLE) for tracing pertinent treatment modalities.
Kubra ÖZTÜRK +2 more
exaly +2 more sources
Invasive aspergillosis: a severe infection in juvenile systemic lupus erythematosus patients
Lupus, 2012 Infections are an important cause of morbidity and mortality in juvenile systemic lupus erythematosus (JSLE). Among them, invasive aspergillosis (IA), which is usually related to immunosuppressed patients, has been rarely reported in JSLE.
Clovis A Silva, Nadia E Aikawa
exaly +2 more sources
Complement and antibody primary immunodeficiency in juvenile systemic lupus erythematosus patients
Lupus, 2011 Objective: To evaluate the frequency of primary immunodeficiencies (PID) in juvenile systemic lupus erythematosus (JSLE) patients. Methods: Some 72 JSLE patients were analyzed for levels of immunoglobulin classes and IgG subclasses and early components ...
Clovis A Silva +2 more
exaly +2 more sources
Juvenile systemic lupus erythematosus in Nigeria
Lupus, 2016Juvenile systemic lupus erythematosus (JSLE) is a complex multisystemic autoimmune disorder of unknown cause. It accounts for about one in five cases of SLE. The tendency for SLE to run a fulminant course when it starts in childhood has made JSLE a potentially more severe disease than adult SLE.
O O, Adelowo +3 more
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Hypophosphatemia in juvenile patients with systemic lupus erythematosus
Pediatrics International, 2003Abstract Background : Hypophosphatemia is observed in both genetic diseases and acquired disorders, although it has never been described in systemic lupus erythematosus (SLE). The present study reports hypophosphatemia observed in patients with SLE, and investigates whether serum phosphorus (P) concentration is ...
Ikuma, Fujiwara +4 more
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Hepatic Manifestations in Juvenile Systemic Lupus Erythematosus
Recent Patents on Inflammation & Allergy Drug Discovery, 2014Juvenile systemic lupus erythematosus (JSLE) is a chronic autoimmune disease characterized by multisystem involvement and diverse clinical and serological manifestations. Clinically significant hepatic disease is generally regarded as unusual in JSLE, but many studies have showed that hepatic disease may be more common in SLE than was usually thought ...
Mortada H, El-Shabrawi, Mona I, Farrag
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Superoxide release in juvenile systemic lupus erythematosus
Rheumatology International, 2011The objective of this study was to analyze the un-stimulated and stimulated release of superoxide anion (O(2) (-)) by granulocytes and monocytes in juvenile systemic lupus erythematosus (jSLE). The un-stimulated and phorbol myristate acetate (PMA, 30 nM)-induced O(2) (-)by granulocytes and monocytes were determined in six different times of incubation ...
Roberto, Marini +4 more
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Juvenile systemic lupus erythematosus
2016Juvenile-onset systemic lupus erythematosus (JSLE) is similar to adult-onset SLE, but there are distinct differences in clinical features, serology, and management requirements. It is more aggressive than adult-onset SLE with frequent renal and haematological manifestations and higher mortality rates.
Claire Louise Murphy +2 more
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