Results 41 to 50 of about 85,032 (235)

Structural Insights Into CO2 Transport Pathways in a W‐Formate Dehydrogenase: Structural Basis for CO2 Reduction

open access: yesAngewandte Chemie, EarlyView.
Integrated structural analysis of N. vulgaris formate dehydrogenase AB, an enzyme with applications in climate change mitigation, is reported. The substrate/product diffusion pathways were fully mapped, and a retention site was identified that transiently holds substrates and has a key role in CO2‐reducing activity.
Guilherme Vilela‐Alves   +8 more
wiley   +2 more sources

De andre tegn på kroppen

open access: yesKvinder, Køn & Forskning, 2019
Dette essay udspringer af vores erfaringer med at blive forvekslet med hinanden i konteksten af dansk akademia. At blive forvekslet er selvfølgelig ikke en erfaring, der er forbeholdt østasiatiske kroppe som vores.
Jin Hui Li   +3 more
doaj   +1 more source

A minimal physiologically based pharmacokinetic model to investigate FcRn-mediated monoclonal antibody salvage: Effects of Kon, Koff, endosome trafficking, and animal species

open access: yesmAbs, 2018
Manipulation of binding affinity between monoclonal antibodies (mAbs) and the neonatal Fc receptor (FcRn) has been leveraged to extend mAb half-life; however, the steps required for success remain ambiguous and experimental observations are inconsistent.
Brian M. Maas, Yanguang Cao
semanticscholar   +1 more source

FRONTs pensumarbejde - dekolonisering og antidiskrimination i akademia

open access: yesKvinder, Køn & Forskning, 2019
Henover efteråret 2018 har FRONT kørt FRONTlæser: et initiativ der undersøger diskrimination og kolonialisme i højere uddannelse. FRONT er en studenterdrevet gruppe med dynamisk deltagelse, der arbejder med antidiskrimination og dekolonisering på alle ...
Gruppen FRONT
doaj   +1 more source

Take me to Neverland

open access: yesEdda, 2017
Med artiklen «Take me to Neverland» forsøger jeg med begrebet «voksenfobi» at afkode en dominerende tendens i den danske samtidslitteratur, hvor et stigende antal unge forfattere gennem deres værker udtrykker en meget distinkt, hysterisk modvilje mod det
Camilla Schwartz
doaj   +1 more source

Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells

open access: yesAdvanced Science, EarlyView.
Alkyltriphenylphosphonium, exemplified by TPP+‐C14, preferentially accumulates in mitochondria and selectively binds to cardiolipin, a key phospholipid of the inner mitochondrial membrane, causing loss of mitochondrial membrane potential, severe cellular ATP depletion, and calcium imbalance.
Jin Li   +8 more
wiley   +1 more source

Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1

open access: yesAdvanced Science, EarlyView.
Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency   +19 more
wiley   +1 more source

Molecular mechanism of central nervous system repair by the Drosophila NG2 homologue kon-tiki

open access: yesJournal of Cell Biology, 2016
Glial cells help central nervous system injury repair, but this is limited by the failure of newly produced glial cells to differentiate. Here, Losada-Perez et al.
María Losada-Pérez   +2 more
semanticscholar   +1 more source

Profiling of Integrin Isoforms on Lung‐Tropic Exosomes by Spectrally and Kinetically Multiplexed Single‐Molecule Imaging

open access: yesAdvanced Science, EarlyView.
A spectrally and kinetically multiplexed single‐molecule imaging method is developed, which achieved simultaneous imaging of 12 exosomal proteins at an unparalleled single‐copy resolution. It is found that co‐occurrence of α6 integrin and the pairing β counterpart on single exosomes is essential for lung targeting, providing valuable information for ...
Songlin Liu   +10 more
wiley   +1 more source

Giver kvinder og mænd forskellige karakterer? Køn og karaktergivning på universitetet

open access: yesDansk Universitetspaedagogisk Tidsskrift, 2014
Er kvindelige universitetsansatte mere orienteret mod at hjælpe den enkelte studerende end deres mandlige kolleger, og giver de derfor bedre karakterer?
Lotte Bøgh Andersen   +1 more
doaj   +2 more sources

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