Results 101 to 110 of about 672,646 (267)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

A Comparison of Passive Microwave Emission Models for Estimating Brightness Temperature at L- and P-Bands Under Bare and Vegetated Soil Conditions

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
P-band radiometry has been demonstrated to have a deeper sensing depth than L-band, making the consideration of multilayer microwave interactions necessary. In addition, the scattering and phase interference effects are different at the P-band, requiring
Foad Brakhasi   +11 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

A S/K/Ka Triple-Band Shared-Aperture Antenna Hybridizing Monopole Array and Transmitarray

open access: yesIEEE Open Journal of Antennas and Propagation
This paper presents a triple-band shared-aperture antenna operating in the S-, K-, and Ka-bands. The antenna is based on a modified transmitarray antenna (TA) where a $2\times 2$ monopole array (MA) is integrated into its transmitting surface (TS).
Zi Long Ma, Yang Li Geng
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Design of K-Band Substrate Integrated Waveguide Band-Pass Filter with High Rejection

open access: yesJournal of Microwaves, Optoelectronics and Electromagnetic Applications
This article presents the design of K-band Substrate Integrated Waveguide (SIW) Band-pass filter with high rejection, by using the topology with iris and the SIW resonators.
Ahmed Rhbanou   +2 more
doaj   +1 more source

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