Testing Special Cases of the GB2 Distribution: Comment and an Extension
We extend earlier work (Griffiths and Hill, 2025) by pointing out that a score test developed by Prentice (1975) for testing whether a normal distribution is an adequate representation of the log of a GB2 random variable is suitable for testing whether a
Hill, R. Carter, Griffiths, William
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Marginalized Gromov Flow Particle Filter-Based Track-Before-Detect Algorithm for Marine Targets. [PDF]
Sensors (Basel)Zhang F, Liu C.
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Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Thermalization of quantum light induced by classical nonlinear wave dynamics. [PDF]
Sci AdvChahrour F +4 more
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Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
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Identifiability of Large Phylogenetic Mixtures for Many Phylogenetic Model Structures. [PDF]
Bull Math BiolKagy B, Sullivant S.
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Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
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Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Predominance of NDM and OXA-48 Carbapenemase Coharboring Among Carbapenem Nonsusceptible Enterobacterales Isolates From Clinical Specimens at a Tertiary Hospital in Vietnam. [PDF]
Int J MicrobiolLuong LH +6 more
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