Results 191 to 200 of about 2,187,925 (266)
Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel +14 morewiley +1 more sourceGeographic distribution of beta-lactamase gene families in K. pneumonia.
Markus H. K. Johansson (17241650), Thomas N. Petersen (13730107), Sidsel Nag (4877182), Timmie M. R. Lagermann (22075470), Laura E.K. Birkedahl (22075473), Silva Tafaj (16439315), Susan Bradbury (22075476), Peter Collignon (704972), Denise Daley (116434), Victorien Dougnon (6813662), Kafayath Fabiyi (17059971), Boubacar Coulibaly (44654), Réné Dembélé (22075479), Natama Magloire (22075482), Isidore J. Ouindgueta (22075485), Zenat Z. Hossain (4865356), Anowara Begoum (22075488), Deyan Donchev (22075491), Mathew Diggle (9964780), LeeAnn Turnbull (22075494), Simon Lévesque (357199), Livia Berlinger (51201), Kirstine K. Søgaard (10332092), Paula D. Guevara (22075497), Carolina Duarte (790308), Panagiota Maikanti (22075500), Jana Amlerova (619407), Pavel Drevinek (23044), Jan Tkadlec (659815), Milica Dilas (18966543), Achim Kaasch (3529964), Henrik T. Westh (22075503), Mohamed A. Bachtarzi (22075506), Wahiba Amhis (22075509), Carolina E.S. Salazar (22075512), José E. Villacis (18323458), Mária A. D. Lúzon (22075515), Dàmaris B. Palau (22075518), Claire Duployez (22075521), Maxime Paluche (22075524), Solomon Asante-Sefa (22075527), Mie Møller (20717248), Margaret Ip (225393), Ivana Mareković (17641059), Agnes Pál-Sonnevend (22075530), Clementiza E. Cocuzza (22075533), Asta Dambrauskiene (22075536), Alexandre Macanze (22075539), Anelsio Cossa (4162072), Inácio Mandomando (89296), Philip Nwajiobi-Princewill (13887963), Iruka N. Okeke (8088743), Aderemi O. Kehinde (22075542), Ini Adebiyi (13450265), Ifeoluwa Akintayo (22075545), Oluwafemi Popoola (19213640), Anthony Onipede (22075548), Anita Blomfeldt (849095), Nora E. Nyquist (22075551), Kiri Bocker (22075554), James Ussher (20917892), Amjad Ali (51075), Nimat Ullah (16988143), Habibullah Khan (19995135), Natalie W. Gustafson (22075557), Ikhlas Jarrar (22075560), Arif Al-Hamad (22075563), Viravarn Luvira (5410946), Wantana Paveenkittiporn (776171), Irmak Baran (22075566), James C. L. Mwansa (22075569), Linda Sikakwa (6760310), Kaunda Yamba (14526442), Frank M. Aarestrup (7486067) +73 moreopenalex +1 more sourceAdaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová +10 morewiley +1 more sourceLongitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay +15 morewiley +1 more source