Results 161 to 170 of about 2,006,480 (313)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Peningkatan Kualitas Jaringan Pada Vehicle Ad-Hoc Network Menggunakan Algoritma Simple K-Means

Techno.Com, 2018
Vehicle Ad-hoc Network atau lebih dikenal dengan istilah VANET merupakan teknologi jaringan komunikasi data yang dapat diimplementasikan pada kendaraan di jalan raya.
Ronald Adrian, Fahmizal Fahmizal, Nur Rohman Rosyid   +2 more
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Visual field prediction using K-means clustering in patients with primary open angle glaucoma. [PDF]

Int J Ophthalmol
Lee J, Kim J, Kim H, Moon S, Kim E, Jeong S, Yang H, Lee J.   +7 more
europepmc   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Pediatric asthma population risk stratification using k-means clustering. [PDF]

J Asthma
Rezaeiahari M, Eyimina A, Boyd M, Brown CC, Perry TT, Ararat E, Tilford JM, Jefferson AA.   +7 more
europepmc   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Classifying Cannabis sativa chemovars using K-means analysis of elemental composition. [PDF]

J Cannabis Res
Lukomski B.
europepmc   +1 more source

ANALISIS PERTUMBUHAN DAN PERKEMBANGAN ANAK DI WILAYAH PEDESAAN MENGGUNAKAN ALGORTIMA K-MEANS

Dewi Rahmawati, Bambang Irawan, Agus Bahtiar   +2 more
openalex   +2 more sources

Multi-Depot Capacitated Vehicle Routing Problem by Using Stable Marriage and K-Means Clustering to Minimize Number of Unserved Customers and Total Travel Distance

, 2021
Purba Daru Kusuma, Meta Kallista, A Ahmed, J Sun, K Braekers, K Ramaekers, I Van Nieuwenhuyse, L Bertazzi, N Secomandi, N Normasari, V Yu, C Bachtiar, Sukoyo, B Khaoula, B Youssef, B Ghizlane, A Annouch, A Bellabdaoui, Z Peya, M Akhnand, T Sultana, M Rahman, W Zhang, Y Gajpal, S Appadoo, Q Wei, B Peng, L Wu, Y Yi, X Chen, J Lin, W Zhou, O Wolfson, S Shao, W Guan, B Ran, Z He, J Bi, M Okulewicz, J Mandziuk, I Cuevas, S Omar, C Morales, J Flores, J Vazquez, X Ge, Z Zhu, Y Jin, U Yildirim, Y Kuvvetli, K Ouaddi, Y Benadada, F Mhada, Q Qiao, F Tao, H Wu, X Yu, M Zhang, A Alhujaylan, M Hosny, H Jahangir, M Mohammadi, S Pasandideh, N Nobari, D Gale, L Shapley, A Abdulkadiroglu, Y Che, Y Yasuda, R Manlove, S Scott, R Bai, J Li, J Atkin, G Kendall, M Kummel, F Busch, D Wang, P Kusuma, N Rachmaningrum, C Wu, B Yan, R Yu, B Yu, X Zhou, Y Yu, N Chen, R Irving, P Leather, D Gusfield   +89 more
openalex   +1 more source