Results 281 to 290 of about 2,006,480 (313)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

An Improved Multi-Threshold Data Quality Control Algorithm for W-Band Cloud Radar Based on K-means Clustering

open access: green
Zhao Shi   +5 more
openalex   +1 more source

Secure cloud computing: leveraging GNN and leader K-means for intrusion detection optimization. [PDF]

open access: yesSci Rep
Dugyala R   +7 more
europepmc   +1 more source

k-Means NANI: An Improved Clustering Algorithm for Molecular Dynamics Simulations. [PDF]

open access: yesJ Chem Theory Comput
Chen L   +4 more
europepmc   +1 more source

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