Results 11 to 20 of about 55,507 (190)

The Design and Construction of K11: A Novel α-Helical Antimicrobial Peptide [PDF]

open access: yesInternational Journal of Microbiology, 2012
Amphipathic α-helical antimicrobial peptides comprise a class of broad-spectrum agents that are used against pathogens. We designed a series of antimicrobial peptides, CP-P (KWKSFIKKLTSKFLHLAKKF) and its derivatives, and determined their minimum ...
Huang Jin-Jiang   +4 more
doaj   +3 more sources

Identification of Bacteriophage K11 Genomic Promoters for K11 RNA Polymerase [PDF]

open access: yesBMB Reports, 2002
Only one natural promoter that interacts with bacteriophage K11 RNA polymerase has so far been identified. To identify more, in the present study restriction fragments of the phage genome were individually assayed for transcription activity in vitro. The K11 genome was digested with two 4-bp-recognizing restriction enzymes, and the fragments cloned in ...
Kyung Goo, Han   +4 more
openaire   +2 more sources

K11-Linked Polyubiquitination in Cell Cycle Control Revealed by a K11 Linkage-Specific Antibody [PDF]

open access: yesMolecular Cell, 2010
Polyubiquitination is a posttranslational modification where ubiquitin chains containing isopeptide bonds linking one of seven ubiquitin lysines with the C terminus of an adjoining ubiquitin are covalently attached to proteins. While functions of K48- and K63-linked polyubiquitin are understood, the role(s) of noncanonical K11-linked chains is less ...
Matsumoto, Marissa L.   +11 more
openaire   +2 more sources

Synthesis and Analysis of K11-Linked Ubiquitin Chains [PDF]

open access: yesBiophysical Journal, 2012
Much has been learned about protein ubiquitination by studying the structural, biochemical, and biophysical properties of ubiquitin chains in vitro. However, these analyses were limited to K48-, K63-linked, and linear ubiquitin chains. Only recently, enzymatic and chemical assembly systems for the remaining chain types have been developed.
Anja, Bremm, David, Komander
openaire   +3 more sources

Beamline K11 DIAD: a new instrument for dual imaging and diffraction at Diamond Light Source [PDF]

open access: yesJournal of Synchrotron Radiation, 2021
The Dual Imaging and Diffraction (DIAD) beamline at Diamond Light Source is a new dual-beam instrument for full-field imaging/tomography and powder diffraction. This instrument provides the user community with the capability to dynamically image 2D and 3D complex structures and perform phase identification and/or strain mapping using micro-diffraction.
Christina Reinhard   +23 more
openaire   +2 more sources

Macrophage TRIM21 Inhibition Ameliorates Murine Acute Pancreatitis via PHB2-Mediated Mitochondrial Stabilization. [PDF]

open access: yesAdv Sci (Weinh)
Macrophage‐derived TRIM21 drives the progression of AP via ubiquitin‐proteasome‐mediated degradation of PHB2, leading to impaired PHB2‐mediated mitophagy. Therefore, accumulation of cytosolic mtDNA hyperactivates the cGAS‐STING signaling axis, thereby amplifying inflammatory cascades.
Xu Y   +7 more
europepmc   +2 more sources

Twist transition of nematic hyperbolic hedgehogs [PDF]

open access: yes, 2014
Stability of an idealized hyperbolic hedgehog in a nematic liquid crystal against a twist transition is investigated by extending the methodology of Rüdinger and Stark [Liq. Cryst.
Fukuda, J-I, James, R
core   +1 more source

K11 ubiquitin linkages in mitotic exit [PDF]

open access: yes, 2015
The ubiquitin proteasome system (UPS) directs programmed destruction of key cellular regulators via posttranslational modification of its targets with polyubiquitin chains.
De Luca, Maria   +4 more
core   +2 more sources

Assessment of Damage Caused by the Reduction of Daylight Lighting Duration of Residential Constructions in the Conditions of the Republicof Moldova

open access: yesReal Estate Management and Valuation, 2023
This paper examines the material damage caused to the owner of the property as a result of the violation of the design rules. This phenomenon was observed by the authors participating in the period 2018-2021 in the assessment of over 500 construction ...
Albu Svetlana, Ivanov Valeriu, Albu Ion
doaj   +1 more source

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