Results 121 to 130 of about 169,777 (262)

CXCL3 Antagonism Reverses Systemic Antitumor Immune Memory Impairment Associated With High Tumor Burden and Sensitizes Anti‐PD‐1 Therapy

open access: yesAdvanced Science, EarlyView.
This study reveals that large tumors secrete more chemokine CXCL3, which recruits immunosuppressive neutrophils to the periphery, thereby impairing the activation and memory of systemic tumor‑reactive CD8+ T cells. CXCL3 antagonism restores systemic immune memory and enhances the antitumor efficacy of anti‑PD‑1 therapy, offering a potential strategy to
Ji Wang   +15 more
wiley   +1 more source

CD112 Lactylation Drives Dual Immune Evasion From CD8+ T Cells and NK Cells

open access: yesAdvanced Science, EarlyView.
AARS2 functions as an intracellular lactate sensor and lactyltransferase, catalyzing CD112 K412 lactylation to block ubiquitination‐dependent degradation and stabilize CD112. This pathway suppresses CD8+ T‐cell and NK‐cell cytotoxicity, enabling dual immune evasion.
Zhuoshuo Xu   +6 more
wiley   +1 more source

Trends in prognosis and use of SGLT2i and GLP-1 RA in patients with diabetes and coronary artery disease

open access: yesCardiovascular Diabetology
Objective To explore trends in prognosis and use of glucose-lowering drugs (GLD) in patients with diabetes and coronary artery disease (CAD). Research design and methods All patients with diabetes and CAD undergoing a coronary angiography between 2010 ...
Viveca Ritsinger   +4 more
doaj   +1 more source

Role of Vitamin K2 in Human Body: A Mini Review

open access: yesThe Iraqi Journal of Medical Sciences
Vitamin K2 (Menaquinone) stands out from other members of the vitamin K family due to its unique molecular structure. It is primarily found in meat and dairy products or converted from K1 in the gut.
Majid H. Ahmed, Zainab H. Hashim
doaj   +1 more source

GLONASS-K2 signal analysis

open access: yesGPS Solutions
AbstractK2 is a new generation of GLONASS satellites that provides code division multiple access (CDMA) signals in the L1, L2 and L3 frequency bands in addition to legacy L1 and L2 signals based on frequency division multiple access (FDMA) modulation.
Thoelert, Steffen   +2 more
openaire   +2 more sources

Trap‐Programmable Ruddlesden–Popper Perovskite Nanocrystals for Persistent Optoelectronic Memory and Photonic Synapses

open access: yesAdvanced Science, EarlyView.
This work presents trap‐programmable Ruddlesden–Popper perovskite nanocrystals for ultralong‐lived optical memory and photonic synapses. Layer‐controlled octahedral distortion modulates trap depth and carrier‐storage kinetics, enabling persistent luminescence beyond 5000 s at room temperature.
Xuanyu Zhu   +12 more
wiley   +1 more source

10. K2-3d [Milky way Planets]

open access: yes, 2018
<p>10. K2-3d [Milky way Planets]</p> <p>In this video, visualization of K2-3d is carried out; various positions of K2-3d in the space</p ...
Mitra, Manu (6004697), Mitra, Manu
core   +1 more source

An Integrated Artificial Intelligence Framework for Nanomedicine Engineering

open access: yesAdvanced Science, EarlyView.
This review outlines a closed‐loop AI ecosystem for nanomedicine engineering. By synergizing multimodal data harmonization, objective‐driven AI architectures, and automated high‐throughput validation, this “Design‐Make‐Test‐Analyze” (DMTA) workflow transforms traditional heuristic formulation into a predictive, self‐optimizing paradigm, accelerating ...
Meichen Dong   +10 more
wiley   +1 more source

Kollektiv mobilitet : Ett scenario för hållbar samhällsutveckling

open access: yes, 2023
Trafikverket har fått i uppdrag av regeringen att genomföra informations- och kunskapshöjande insatser som avser mobilitet som en tjänst. Mobilitet som tjänst har beskrivits som en lösning för att minska samhällets beroende av den privata bilen, i ...
Eriksson, Eva-Lena, Hultén, John
core  

Coordination‐Asymmetry‐Regulated Reconstruction of Electron‐Rich Cu Sites for pH‐Dependent Nitrate‐to‐Ammonia Electrocatalysis

open access: yesAdvanced Science, EarlyView.
Distinct initial Cu coordination environments drive different pH‐dependent structural evolution pathways, resulting in divergent nitrate reduction activity and behavior. ABSTRACT Electrocatalytic nitrate reduction reaction (e‐NO3RR) offers a promising route to valorize nitrate‐contaminated wastewater while enabling sustainable ammonia production ...
Shih‐Ching Huang   +11 more
wiley   +1 more source

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