Results 131 to 140 of about 169,777 (262)

Electron‐Rich Nickel Enabled by Charge Transfer in Multimetal Nanostructures for Efficient Ammonia‐to‐Hydrogen Conversion

Advanced Science, EarlyView.
A charge‐transfer‐engineered Ni catalyst derived from an atomically mixed layered precursor enables efficient ammonia‐to‐hydrogen conversion. Cr‐to‐Ni electron transfer creates electron‐rich Ni active sites that favor NH3 adsorption, modify the dehydrogenation energetics, and weaken N2 binding to facilitate product desorption. This electronically tuned
Donghyeok Kim, Su‐Jin Kim, Gayeong Kim, Hyoseok Kim, Jongkyoung Kim, Myeung‐Jin Lee, Bora Jeong, Minkyu Kim, Hong‐Dae Kim, Seungho Cho   +9 more
wiley   +1 more source

K1 Klebsiella pneumoniae is more conserved than K2 for both virulence plasmid and chromosome

BMC Genomics
Objective To illustrate the differences between K1 and K2 Klebsiella pneumoniae strains. Methods Totally 68 K1 and 99 K2 K. pneumoniae strains from GenBank were analyzed for virulence genes, sequence types (STs), restriction-modification (R-M) systems ...
Piaopiao Dai, Tingting Huang, Xinru Ye, Shuli Mi, Jin Zhang, Xinhua Luo, Dakang Hu, Haifang Zhang   +7 more
doaj   +1 more source

Structural Variants in the Human Genome Associated With Gut Microbiome and Blood Metabolic Traits With Potential Causal Links

Advanced Science, EarlyView.
Based on a multi‐omics cohort of 2002 individuals comprising high‐depth whole‐genome and metagenomic sequencing data, blood metabolites, and detailed questionnaires, we identified 138 859 high‐confidence SVs, uncovering 36 significant SV–microbiome associations and 48 SV–blood metabolite associations.
Qun Zhou, Keqing Wang, Junhong Chen, Haoyu Wang, Xinjiang Tan, Xuanlin Huang, Zhiyin Lin, Xun Xu, Xin Jin, Shaoqiao Zhang, Liang Xiao, Yuanqiang Zou, Tao Zhang, Xiaomin Liu   +13 more
wiley   +1 more source

A Fluorogenic Cysteine‐Tetrapeptide Tagging Strategy for Nonperturbative Protein Labeling and Protein–Ligand Interaction Tracking

Advanced Science, EarlyView.
A compact Phe‐Cys‐Pro‐Phe (FCPF) tag and an environment‐sensitive SBD‐Cl‐derived probe form a sequence‐selective fluorogenic pair for wash‐free live‐cell protein imaging. This minimally perturbing chemistry allows flexible insertion at termini or loops, produces strong fluorescence upon local microenvironment confinement, supports FRET‐assisted ...
Xiao Wang, Xingcan Pan, Yongling Ying, Ziqian Bai, Jingming Zhang, Zhuang Shao, Jialiang Qian, Hongwei Li, Ning Zhang, Fan Yang, Yuan Liu, Xing Yang   +11 more
wiley   +1 more source

Harnessing Methylselenol (CH3SeH): A Highly Effective Platform for Stimuli‐Responsive Delivery With Therapeutic Potential

Advanced Science, EarlyView.
Tools for controlled selenol delivery are crucial for exploring Se‐related biology and medicine, but compound platforms for triggerable release of CH3SeH remain lacking. Herein, we report the first general triggered platform (TD‐MSe) for efficient cyclization release of CH3SeH in live cells.
Wenfang Liang, Liyue Wang, Xuan Wang, Xinran Li, Hao Xing, Lu Sun, Zhen Xi, Long Yi   +7 more
wiley   +1 more source

Vitamin K2 inhibits PGE2-mediated osteoblast ferroptosis by upregulation of CBR1 via the Nrf2/Keap1 pathway

Communications Biology
Osteoporosis is increasingly attracting attention. Studies have indicated a correlation between vitamin K2 levels and bone mass, but the specific mechanisms remain unclear. Therefore, this study aims to further elucidate the specific molecular mechanisms
Lin Tao, Hongyang Li, Jinpeng Wang, Qichang Liu, Wenhai Cao, Yue Zhu   +5 more
doaj   +1 more source

Therapeutic Peptide‐Programmed Liquid‐Crystalline Topology Switching for pH‐Gated Postoperative Cancer Immunotherapy

Advanced Science, EarlyView.
A VDAP‐programmed liquid‐crystalline depot enables pH‐responsive postoperative immunotherapy for triple‐negative breast cancer. VDAP stabilizes a leakage‐resistant HII mesophase through peptide–lipid electrostatic assembly, whereas tumor acidosis unlocks the matrix and promotes graded topology remodeling toward a bicontinuous Im3̄m cubic phase for ...
Yan Yan, Bin Chen, Yanqing Wang, Yuxi Hou, Zhenlin Ma, Zini Yang, Xia Yin, Yiling Chen, Litao Huang, Menghan Cai, Xinlin Liu, Yi Zhun Zhu, Li Ye   +12 more
wiley   +1 more source

Large Oncosomes Induce Pro‐Metastatic Stromal‐Myeloid Reprogramming

Advanced Science, EarlyView.
Large oncosomes systemically reprogram bone marrow mesenchymal stem cells through innate nucleic acid sensing, driving inflammatory and immunosuppressive remodeling that supports a metastasis‐permissive bone marrow environment, revealing a novel tumor‐host communication axis in cancer. ABSTRACT Bone metastasis can be facilitated by systemic remodeling,
Taylon Felipe Silva, Virginia Marcia Concato‐Lopes, Fatima Bedier, Lauren Newman, Diana Kitka, Jamelle Brown, Blandine Victor, Minhyung Kim, Tatyana Vagner, Catherine Grasso, Dmitriy Sheyn, Sungyong You, Michael R. Freeman, Fayyaz S. Sutterwala, Helen S. Goodridge, Caroline Jefferies, Paola de Candia, Jlenia Guarnerio, Dolores Di Vizio   +18 more
wiley   +1 more source

Overcoming the *H‐NOx Coupling Bottleneck via Palladium‐Enabled Relay Catalysis on CuCo2O4 Toward Ampere‐Level Nitrate‐to‐Ammonia

Advanced Science, EarlyView.
Pd‐doped hollow spiny CuCo2O4 microspheres deliver ampere‐level electrocatalytic nitrate to ammonia. Cu and Co sites undergo relay catalysis for sequential nitrate reduction, while Pd accelerates water dissociation to supply abundant active hydrogen (*H).
Yuhuan Cui, Yingying Xu, Jingyao Guo, Yao Liu, Yuxuan Li, Zixuan Feng, Yitong Zhou, Yongjun Gao, Zhili Wang   +8 more
wiley   +1 more source

Terahertz Channel Modeling, Estimation and Localization in RIS‐Assisted Systems

Advanced Electronic Materials, EarlyView.
Reconfigurable intelligent surfaces have become a recent intensive research focus. Based on practical applications, channel strategies for RIS‐assisted terahertz wireless communication systems are categorized into three different types: channel modeling, channel estimation, and channel localization.
Hongjing Wang, Weipeng Wang, Xuan Cong, Shiyu Wang, Gao Li, Sen Gong, Lin Huang, Hongxin Zeng, Yaxin Zhang, Ziqiang Yang   +9 more
wiley   +1 more source