[Cholesterol Metabolism and Tumor Immunity]. [PDF]
Luo N, Shi RC, Dai RY, Miao HM.
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[The role of the PI3K/AKT signaling pathway in DADS-induced apoptosis of K562 cells]. [PDF]
Xiao L, Yin XC, Cao QQ.
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Effect of lathyrol derivatives on non-small cell lung cancer and the possible mechanism. [PDF]
Yan Y +6 more
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[METTL3-mediated m<sup>6</sup>A modification promotes FOXO3 expression and anthracycline resistance in acute myeloid leukemia cells through autophagy regulation]. [PDF]
Zhang X +5 more
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[Recent advances in isolation and detection of circulating tumor cells with a microfluidic system]. [PDF]
Cao R, Zhang M, Yu H, Qin J.
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Research of RNase A Chemical Modification by Monomethoxypoly (Ethylene Glycol)
该文选取牛胰核糖核酸酶(RNaseA)为模型蛋白,对聚乙二醇修饰蛋白的技术以及修饰对蛋白性质的影响做了较为系统的研究.实验采用单甲氧基聚乙二醇(MPEG)为修饰剂.该文优化了MPEG的N-羟在琥珀酰亚胺活化法以及MPEG的1,1’-二咪唑代碳酸活化法.分别得到对蛋白质活性影响较小,修饰活性较高且较为稳定的活化产物MPEG-SS及MPEG-CDI.为了确定蛋白质的平均修饰度,该文采用TNBS法和毛细管电泳法两种方法对经MPEG-SS修饰的RNaseA进行了测定,得到了可以相互印证的结果 ...
张颖
core
[Progress and prospect of separation and analysis of single-cell and single-particle exosomes]. [PDF]
Bu AX, Wu GY, Hu LH.
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[Targeted suppression of miRNA-21 inhibit K562 cells growth through PTEN-PI3K/AKT signaling pathway]. [PDF]
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[Research progress of iron metabolism and ferroptosis in myeloid neoplasms]. [PDF]
Wang Y, Feng W, Wang F, Min J.
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[Construction of CD138-targeted chimeric antigen receptor- modified T cells and their effect in multiple myeloma therapy]. [PDF]
Guo CC +8 more
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