Results 41 to 50 of about 192 (134)

Lithology modulates soil priming effect via resource limitations and bacterial community structure

open access: yesFunctional Ecology, Volume 40, Issue 1, Page 176-190, January 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract The soil priming effect (PE), triggered by root exudate inputs that stimulates microbial activity and drives significant soil carbon (C) losses in terrestrial ecosystems.
Xinyu Hou   +4 more
wiley   +1 more source

Matrine induces apoptosis in hepatocellular carcinoma through Bid-mediated nuclear translocation of AIF [PDF]

open access: yes, 2013
肝癌是一种常见的恶性肿瘤,它严重威胁着人类的健康。然而,由于肝癌本身所具有的生物学特性,使其成为目前尚缺乏有效治疗手段的疾病。苦参碱是从我国传统中药苦参的干燥根中提取出的一种生物碱活性成分,分子式为C15H24N2O,具有广泛的药理学作用。近年来的研究表明,苦参碱能在体内、外对多种肿瘤细胞起作用,诱导肿瘤细胞凋亡。然而,苦参碱诱导肿瘤细胞凋亡的作用机制还不明确。 本论文以人肝癌细胞系HepG2及裸鼠荷肝癌模型为研究对象,探讨苦参碱的抗肿瘤作用及原理。通过MTT法、PI染色法、流式细胞术 ...
周欢
core  

Genetic Confirmations of Dwarf Lemurs Across Madagascar Highlights Complex Biogeographic Patterns 马达加斯加全境鼠狐猴的遗传确认揭示了复杂的生物地理模式

open access: yesIntegrative Conservation, Volume 4, Issue 4, Page 665-674, December 2025.
Using a diagnostic mitochondrial marker gene, we document the presence of furry‐eared dwarf lemurs, a species known from Madagascar's eastern montane rainforests, in several forest fragments across the island's central highlands. These findings raise new questions about when this species colonized these sites, how they tolerate these changing and ...
Marina B. Blanco   +27 more
wiley   +1 more source

抗癌新靶点:端粒及端粒酶抑制剂研究进展 [PDF]

open access: yes, 1999
端粒酶在绝大多数恶性肿瘤中特异性表达,这使得人们对肿瘤的抗端粒酶疗法产生了特别的关注.设想以端粒、端粒酶为靶点,通过抑制癌细胞端粒酶活性或直接抑制端粒延长、稳定,而使细胞无法连续增殖,继而进入衰老途径,直至死亡.同时端粒、端粒酶在肿瘤细胞与正常体组织..
杨善民, 郭臻
core  

Performance of non‐invasive prenatal testing in vanishing‐twin and multiple pregnancies: results of TRIDENT‐2 study

open access: yesUltrasound in Obstetrics &Gynecology, Volume 66, Issue 6, Page 738-746, December 2025.
ABSTRACT Objective To evaluate the performance of non‐invasive prenatal testing (NIPT) in vanishing‐twin and multiple pregnancies. Methods This study was conducted as part of the TRIDENT‐2 study, in which NIPT was offered as a first‐tier screening test to women with a multiple pregnancy or vanishing‐twin pregnancy between 1 June 2020 and 31 March 2023 ...
J. C. A. van Eekhout   +86 more
wiley   +1 more source

全蚕粉对免疫功能影响的实验研究 [PDF]

open access: yes, 2009
目的探讨全蚕粉对小鼠免疫功能的影响。方法观察全蚕粉对环磷酰胺所致免疫低下小鼠免疫器官指数、碳廓清功能和血清溶血素的影响。结果全蚕粉可增强正常小鼠免疫功能,显著提高免疫低下小鼠胸腺指数、脾脏指数、碳廓清能力和血清溶血素含量 ...
杨辉   +4 more
core  

Review of additively manufactured zinc alloys by laser powder bed fusion for biomedical applications

open access: yesRare Metals, Volume 44, Issue 11, Page 8262-8291, November 2025.
Graphical abstract AbstractZinc (Zn) and its alloys have emerged as promising candidates for biomedical materials, owing to their controlled degradation kinetics, intrinsic biocompatibility, and the release Zn2+ ions which are known to promote bone regeneration and tissue healing.
Xuan Yang   +5 more
wiley   +1 more source

转染survivin对HLF细胞增殖及凋亡的影响 [PDF]

open access: yes, 2006
【【目的】 探讨survivin基因表达对人肺纤维母细胞(humanlungfibroblast,HLF)增殖、凋亡的影响。【方法】 构建survivin基因真核表达质粒peDNA3.1/SVN;利用脂质体转染法将其转入不表达survivin mRNA的HLF细胞系。连续培养10周。筛选出稳定表达的阳性克隆(HLF/SVN)及转空质粒对照(HLF/K)。用RT-PCR、免疫组化、Western blot检测细胞中survivin、bel-2和caspase3mRNA表达:通过观察细胞生长曲线 ...
张萌   +5 more
core  

A new beef: An analysis of discourse coalitions in the nascent cellular agriculture policy subsystem

open access: yesReview of Policy Research, Volume 42, Issue 6, Page 1404-1427, November 2025.
Abstract A robust approach to examining the nature and influence of coalitions in the policy process is the Advocacy Coalition Framework (ACF), which is especially useful to study policy issues fraught with scientific and technical controversy. Yet, important gaps exist in ACF literature regarding nascent policy subsystems. Consequently, there is scant
Nikki Nadeau, Ramiro Berardo
wiley   +1 more source

Studies on polysaccharides from marine organism, a review [PDF]

open access: yes, 2004
国家自然科学基金资助项目 ...
郑天凌, 黄益丽
core  

Home - About - Disclaimer - Privacy