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Expression of K+–Cl− cotransporters in the α-cells of rat endocrine pancreas
The expression of K+-Cl- cotransporters (KCC) was examined in pancreatic islet cells. mRNA for KCC1, KCC3a, KCC3b and KCC4 were identified by RT-PCR in islets isolated from rat pancreas. In immunocytochemical studies, an antibody specific for KCC1 and KCC4 revealed the expression of KCC protein in alpha-cells, but not pancreatic beta-cells nor delta ...
Davies, Sarah L.+6 more
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Role of basolateral K-CL cotransport in colonic K absorption
Bliss Forbush+5 more
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Intracellular trafficking of the Na‐K‐Cl cotransporter protein
John M. Russell, Chaitanya Pant
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The structure of Na+-K+-Cl− cotransporter 1 [PDF]
A recent study reports the first high-resolution, cryo-electron microscopy-based structure of zebrafish Na+-K+-Cl− cotransporter 1 (NKCC1). This structure provides important insights into the determinants of ion translocation by NKCC1 and other cation-Cl− cotransporters such as NKCC2.
Paul Isenring+2 more
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The K–Cl cotransporter-3 in the mammalian kidney
Current Opinion in Nephrology & Hypertension, 2023Purpose of review We recently localized a new K–Cl cotransporters-3 (KCC3) transporter to the apical membrane of type-B intercalated cells. This gives us an opportunity to revisit the roles of the KCC3 in kidney and integrate the new findings to our current knowledge of the biology of the bicarbonate secreting cells.
Mohammed Z, Ferdaus, Eric, Delpire
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Journal of bioenergetics and biomembranes, 1998
The Na-K-Cl cotransporters are a class of membrane proteins that transport Na, K, and Cl ions into and out of a wide variety of epithelial and nonepithelial cells. The transport process mediated by Na-K-Cl cotransporters is characterized by electroneutrality (almost always with stoichiometry of 1Na:1K:2Cl) and inhibition by the "loop" diuretics ...
Mark Haas, Bliss Forbush
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The Na-K-Cl cotransporters are a class of membrane proteins that transport Na, K, and Cl ions into and out of a wide variety of epithelial and nonepithelial cells. The transport process mediated by Na-K-Cl cotransporters is characterized by electroneutrality (almost always with stoichiometry of 1Na:1K:2Cl) and inhibition by the "loop" diuretics ...
Mark Haas, Bliss Forbush
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Erythrocyte K-Cl cotransport: properties and regulation
American Journal of Physiology-Cell Physiology, 1992Erythrocytes possess a Cl-dependent, Na-independent K transport system cotransporting K and Cl in a 1:1 stoichiometry that is membrane potential independent. This K-Cl cotransporter is stimulated by cell swelling, acidification, Mg depletion, and thiol modification.
Kyoo Hai Ryu+6 more
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K-Cl cotransporter expression in the human kidney
American Journal of Physiology-Cell Physiology, 1998The K-Cl cotransporter protein KCC1 is a membrane transport protein that mediates the coupled, electroneutral transport of K and Cl across plasma membranes. The precise cell type(s) in the kidney that express the K-Cl cotransporter have remained unknown.
Helen Liapis, M. Nag, Deepak M. Kaji
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The Na-K-Cl Cotransporter of Secretory Epithelia
Annual Review of Physiology, 2000▪ Abstract The Na-K-Cl cotransporters are a class of ion transport proteins that transport Na, K, and Cl ions into and out of cells in an electrically neutral manner, in most cases with a stoichiometry of 1Na:1K:2Cl. To date, two Na-K-Cl cotransporter isoforms have been identified: NKCC1, which is present in a wide variety of secretory epithelia and ...
Mark Haas, Bliss Forbush
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American Journal of Physiology-Cell Physiology, 1994
The Na-K-Cl cotransporters are a class of membrane proteins that transport Na, K, and Cl ions into and out of cells in an electrically neutral manner, in most cases with a stoichiometry of 1Na:1K:2Cl. Na-K-Cl cotransporters are present in a wide variety of cells and tissues, including reabsorptive and secretory epithelia, nerve and muscle cells ...
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The Na-K-Cl cotransporters are a class of membrane proteins that transport Na, K, and Cl ions into and out of cells in an electrically neutral manner, in most cases with a stoichiometry of 1Na:1K:2Cl. Na-K-Cl cotransporters are present in a wide variety of cells and tissues, including reabsorptive and secretory epithelia, nerve and muscle cells ...
openaire +3 more sources