Results 261 to 270 of about 5,024,889 (297)
Some of the next articles are maybe not open access.
Effects of rutin on oxidative stress in mice with kainic acid-induced seizure.
Journal of Integrative Medicine, 2013OBJECTIVE Flavonoids are present in foods such as fruits and vegetables. Several studies have demonstrated a relationship between the consumption of flavonoid-rich foods and prevention of human disease, including neurodegenerative disorders.
Marjan Nassiri-Asl+6 more
semanticscholar +1 more source
Neuronal mapping with kainic acid
Trends in Neurosciences, 1978Abstract Kainic acid, found naturally-occurring in sea-weed, is a substance which is structurally-related to the putative neurotransmitter, glutamate. Kainic acid has now entered the neuroscientists armoury of equipment as a potent and selective neurotoxin which will cause the fast degeneration of neurones with cell bodies in the area of injection ...
openaire +2 more sources
Total synthesis of (-)-α-kainic acid via chirality transfer through Ireland-Claisen rearrangement.
Journal of Organic Chemistry, 2013The total synthesis of (-)-α-Kainic acid is accomplished using a linear strategy involving Noyori asymmetric reduction and chirality transfer through Ireland-Claisen rearrangement as key steps.
Naredla Kesava Reddy, S. Chandrasekhar
semanticscholar +1 more source
Kainic acid: Neurophysiological and neurotoxic actions
Life Sciences, 1979Abstract Kainic acid, an anthelmintic drug structurally related to glutamate, has excitatory electrophysiological actions on neurons in the vertebrate CNS and at the invertebrate neuromuscular junction. Recently, it has been shown to destroy neuronal cell bodies and dendrites in several regions of the vertebrate CNS, while sparing afferent fibers and
openaire +3 more sources
A total synthesis of (±)--kainic acid
Tetrahedron Letters, 1986AbstractThe ring‐opened ylide (II) of the aziridine carboxylic acid ester (I) reacts with the αβ‐unsaturated oxo‐compound (III) to give the pyrrolidine carboxylic acid ester (IV) and its diastereomer (V).
David A. Kell, Philip DeShong
openaire +3 more sources
Journal of the American Chemical Society, 2012
The rhodium-catalyzed ene-cycloisomerization of alkenylidenecyclopropanes provides an atom-economical approach to five-membered carbo- and heterocycles that contain two new stereogenic centers.
P. Evans, P. Inglesby
semanticscholar +1 more source
The rhodium-catalyzed ene-cycloisomerization of alkenylidenecyclopropanes provides an atom-economical approach to five-membered carbo- and heterocycles that contain two new stereogenic centers.
P. Evans, P. Inglesby
semanticscholar +1 more source
Iontophoresis of kainic acid [PDF]
J. A. McCaughran, Edith G. McGeer
openaire +2 more sources
ChemInform Abstract: A New Enantiocontrolled Route to (‐)‐Kainic Acid.
ChemInform, 1997AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Kunio Ogasawara, Mitsuhiro Kawamura
openaire +3 more sources
The activation of glutamate receptors by kainic acid and domoic acid
Natural Toxins, 1998The neurotoxins kainic acid and domoic acid are potent agonists at the kainate and alphaamino-5-methyl-3-hydroxyisoxazolone-4-propionate (AMPA) subclasses of ionotropic glutamate receptors. Although it is well established that AMPA receptors mediate fast excitatory synaptic transmission at most excitatory synapses in the central nervous system, the ...
David R. Hampson, Jerrie Lynn Manalo
openaire +3 more sources
Journal of Agricultural and Food Chemistry, 2012
Green tea is one of the most-consumed beverages due to its taste and antioxidative polyphenols. However, the protective effects of green tea and its constituent, gallic acid (GA), against kainic acid (KA)-induced seizure have not been studied.
Hsiao-Ling Huang+6 more
semanticscholar +1 more source
Green tea is one of the most-consumed beverages due to its taste and antioxidative polyphenols. However, the protective effects of green tea and its constituent, gallic acid (GA), against kainic acid (KA)-induced seizure have not been studied.
Hsiao-Ling Huang+6 more
semanticscholar +1 more source