Results 161 to 170 of about 49,457 (291)

Ada Kale [PDF]

open access: yesBalkanologie, 2002
openaire   +1 more source

Decision Theory and Proof Standards for Future Crimes: Possible Uses and Open Questions

open access: yesBehavioral Sciences &the Law, EarlyView.
ABSTRACT What should be the proof standard for applying preventive criminal sanctions based on an establishment of risk of reoffending? This is an open question in legal systems around the world. Various authors suggest that we can answer it by using decision theory. This approach conceptualises the proof standard as a probabilistic threshold. A person
Hylke Jellema, Johannes Bijlsma
wiley   +1 more source

Legal Professionals Use an Implicit Checklist to Assess Expert Witness Credibility

open access: yesBehavioral Sciences &the Law, EarlyView.
ABSTRACT In a court of law, some forms of evidence are too technical to interpret without the help of an expert witness. However, expert testimony sometimes leads to wrongful conviction. We used an online survey to quantitatively compare how legal professionals (n = 122) and lay people (n = 109) understood what makes an expert witness credible.
Mahensingh Deonaran   +2 more
wiley   +1 more source

Application of commercial ultrafiltration membranes for protein purification by high performance countercurrent membrane purification (HPCMP)

open access: yesBiotechnology Progress, EarlyView.
Abstract High performance countercurrent membrane purification (HPCMP) has emerged as a promising diffusive separation strategy for the purification of recombinant proteins and monoclonal antibodies (mAbs). However, prior studies employed dialysis membranes, which are designed for diffusive separations but have not been validated for biopharmaceutical ...
Aylin Mohammadzadehmarandi   +8 more
wiley   +1 more source

Screening of bispecific antibodies during single cell cloning of recombinant Chinese hamster ovary cell lines to improve titer and product quality

open access: yesBiotechnology Progress, EarlyView.
Abstract Development of therapeutic bispecific antibodies (BsAbs) poses significant manufacturability challenges associated with correct chain pairing and an increased diversity of impurities. Here we address this with a product quality assessment during cell line development (CLD), forgoing the need for genetic characterization during cell line ...
Molly Robinson   +7 more
wiley   +1 more source

Regenerative perfusion bioreactor for biologics production with lower COGs

open access: yesBiotechnology Progress, EarlyView.
Abstract Perfusion bioreactor systems enable intensified bioprocessing with high cell densities and volumetric productivities in monoclonal antibody (mAb) manufacturing. However, their widespread adoption remains constrained by the high consumption of chemically defined cell culture media.
Eric Wynne   +5 more
wiley   +1 more source

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