Results 91 to 100 of about 6,008,931 (310)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Cognitive impairment profile in patients with the m.3243A> G variant in mitochondrial DNA

BMC Neurology
Background The m.3243A>G variant in mitochondrial DNA is associated with a wide spectrum of clinical features ranging from asymptomatic subjects to severely symptomatic patients. Cognitive involvement is one of the clinical features, but its severity and
Satu Winqvist, Mikko Kärppä, Jukka S. Moilanen, Kari Majamaa   +3 more
doaj   +1 more source

Pregnant women follow‐up service, Shewa, Ethiopia

Health Science Reports, 2022
Background and Aims The goal of this study was to demonstrate the effects of factors related with time to developing pre‐eclampsia (PE) among pregnant women follow‐up service at Arerti Primary Hospital.
Dawit BayeHaile, Aragaw EshetieAguade, Moges ZerihunFetene   +2 more
doaj   +1 more source

Kaplan-Meier analysis (product-limit estimate of time to event). [PDF]

, 2013
Kaplan-Meier analysis (product-limit estimate of time to event).
Jorge Alvar (253327), Michel Vaillant (39101), Piero Olliaro (35337), Olivier Lapujade (217600), Byron Arana (392805), Alan Magill (392806), Pierre Buffet (82569), Farrokh Modabber (35109), Max Grogl (4762899)   +8 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Breast Cancer–Specific Survival and Prognostic Factors in a Statewide Oncology Network in Brazil: A Registry‐Linked Retrospective Cohort Study

Cancer Reports
Background Breast cancer survival varies widely across middle‐income settings and may be influenced by clinical stage at diagnosis and access pathways within oncology care networks.
Raphael Manhães Pessanha, Wesley Rocha Grippa, Luiz Cláudio Barreto Silva Neto, Naira Santos D'Agostini, Luís Carlos Lopes‐Júnior   +4 more
doaj   +1 more source

Maximum disease diameter is associated with outcomes in stage II follicular lymphoma treated with radiation therapy alone

Clinical and Translational Radiation Oncology
Purpose: The optimal management of stage II follicular lymphoma (FL) is unclear. Radiation therapy (RT) alone has been the gold standard treatment, but a proportion of patients relapse.
Yi Xu, Belinda A. Campbell, Matthew Chan, Jessica Chan, Pedro Farinha, Christopher P. Venner, David W. Scott, Alina S. Gerrie, Diego Villa, Laurie H. Sehn, Kerry J. Savage, Andrea C. Lo   +11 more
doaj   +1 more source

Cox proportion hazard model for patients with hepatitis disease in Iraq

مجلة بغداد للعلوم, 2009
Cox regression model have been used to estimate proportion hazard model for patients with hepatitis disease recorded in Gastrointestinal and Hepatic diseases Hospital in Iraq for (2002 -2005).
Baghdad Science Journal
doaj   +1 more source

Kaplan-Meier estimate of time to first treatment switch. [PDF]

, 2014
Kaplan-Meier estimate of time to first treatment switch.
Katherine Nedrow (449577), Richard Chambers (449578), Caitlyn T. Solem (568970), Sonya J. Snedecor (449575), Alexandra Khachatryan (449576), Seema Haider (449580), Kit Simpson (568972), Margaret Tawadrous (568971)   +7 more
core   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source