Results 71 to 80 of about 6,008,931 (310)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Influence of Nodal Yield in Individual Neck Dissection Levels on the Survival of Patients With Oral and Oropharyngeal Cancer

open access: yesSoutheastern European Medical Journal, 2020
Introduction: Nodal yield (NY), or the number of collected and analysed lymph nodes in neck dissection, is one of the variables that could supplement the existing TNM classification in order to better stratify patients and their needs for further ...
Ana Kvolik Pavić   +4 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

The Kaplan-Meier Method for Estimating and Comparing Proportions in a Randomized Controlled Trial with Dropouts

open access: yesBiostatistics & Epidemiology, 2017
We propose a method for estimating and comparing proportions of study participants who reached an event of interest during a randomized controlled trial. Standard methods for estimating this proportion include the intent-to-treat method, which counts the
J. Zee, S. Xie
semanticscholar   +1 more source

Survival Analysis and its Associated Factors of Beta Thalassemia Major in Hamadan Province

open access: yesIranian Journal of Medical Sciences, 2015
Background: There currently is a lack of knowledge about the long-term survival of patients with beta thalassemia (BT), particularly in regions with low incidence of the disease.
Reza Zamani   +2 more
doaj  

Comparison of nonparametric estimators versus parametric for reliability function

open access: yesIngeniería Investigación y Desarrollo, 2015
One of the main objectives of the area of realiability is to estimate the function of reliability, where traditionally are used non parametric estimators, being more efficient in sample of big sizes.
Javier Ramírez-Montoya
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Kaplan-Meier estimate of percentage of cardiovascular mortality. [PDF]

open access: yes, 2014
Kaplan-Meier estimate of percentage of cardiovascular mortality.
Yuen-Kwun Wong (521825)   +10 more
core   +1 more source

Kaplan-Meier estimate of time to publication from conference date for pediatric abstracts that reported research conducted in low- and middle-income countries. [PDF]

open access: yes, 2023
Kaplan-Meier estimate of time to publication from conference date for pediatric abstracts that reported research conducted in low- and middle-income countries.
Tory Prynn (17283271)   +15 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

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