Results of expert judgments on the faults and risks with Autosub3 and an analysis of its campaign to Pine Island Bay, Antarctica, 2009 [PDF]
, 2009 Probabilistic risk assessment is a methodology that can be systematically applied to estimate the risk associated with the design and operation of complex systems.
Brito, Mario P., Griffiths, Gwyn
core
Determination of the most appropriate method for extrapolating overall survival data from a placebo-controlled clinical trial of lenvatinib for progressive, radioiodine-refractory differentiated thyroid cancer [PDF]
, 2016 Background: Cost-effectiveness models for the treatment of long-term conditions often require information on survival beyond the period of available data.
Briggs, Andrew +4 more
core +2 more sources
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Cancer Control, 2023 Objectives This retrospective cohort study investigated the association of socioeconomic status with survival outcomes among patients with nasopharyngeal carcinoma in an endemic area of China. Methods The primary endpoint was overall survival.
Dong-Fang Meng MD, PhD +8 more
doaj +1 more source
Collecting duct carcinoma of the kidney: Clinicopathological profile and outcomes
Urological Science, 2023 Purpose: Collecting duct carcinoma of the kidney (CDC) is an aggressive subtype of renal cell carcinoma with a dismal prognosis. The available knowledge concerning optimal management is still unclear. We report the largest single-institutional experience
Abhilash Cheriyan +4 more
doaj +1 more source
Learning Valuation Distributions from Partial Observation
, 2014 Auction theory traditionally assumes that bidders' valuation distributions are known to the auctioneer, such as in the celebrated, revenue-optimal Myerson auction.
Blum, Avrim +2 more
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Are competing risks models appropriate to describe implant failure?
Acta Orthopaedica, 2018 Background and purpose — The use of competing risks models is widely advocated in the arthroplasty literature due to a perceived bias in comparison of simple Kaplan–Meier estimates.
Adrian Sayers +3 more
doaj +1 more source
The Distribution of Metallicity in the IGM at z~2.5: OVI and CIV Absorption in the Spectra of 7 QSOs
, 2004 We present a direct measurement of the metallicity distribution function for the high redshift intergalactic medium. We determine the shape of this function using survival statistics, which account for both detections and non-detections of OVI and CIV ...
Boyle B. J. +4 more
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source