Results 61 to 70 of about 2,137,840 (268)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Survival Analysis and its Associated Factors of Beta Thalassemia Major in Hamadan Province

Iranian Journal of Medical Sciences, 2015
Background: There currently is a lack of knowledge about the long-term survival of patients with beta thalassemia (BT), particularly in regions with low incidence of the disease.
Reza Zamani, Salman Khazaei, Shahab Rezaeian   +2 more
doaj  

Kaplan-Meier survival estimate of treatment outcomes by 12 months post RR/MDR-TB treatment initiation.

, 2018
Kaplan-Meier survival estimate of treatment outcomes by 12 months post RR/MDR-TB treatment initiation.
Ian Sanne (170641), Denise Evans (288201), Sydney Rosen (213204), Kamban Hirasen (3331569), Lawrence Long (320846), Rebecca Berhanu (442834)   +5 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Adjuvant Chemotherapy Benefit in Elderly Stage II/III Colon Cancer Patients

Frontiers in Oncology, 2022
BackgroundStudies providing more evidence to guide adjuvant chemotherapy decisions in elderly colon cancer patients are expected. MethodsWe obtained data from the Surveillance, Epidemiology and End Results (SEER) database between 2004 and 2012.
Xin Chen, Junhao Tu, Xiaolan Xu, Wen Gu, Lei Qin, Haixin Qian, Zhenyu Jia, Chuntao Ma, Yinkai Xu   +8 more
doaj   +1 more source

Kaplan-Meier survival estimate for investing and non-investing firms (medium and large firms).

, 2016
Kaplan-Meier survival estimate for investing and non-investing firms (medium and large firms).
Dejan Kovac (2936430), Vuk Vukovic (817607), Boris Podobnik (709142), Nikola Kleut (2936427)   +3 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Influence of Nodal Yield in Individual Neck Dissection Levels on the Survival of Patients With Oral and Oropharyngeal Cancer

Southeastern European Medical Journal, 2020
Introduction: Nodal yield (NY), or the number of collected and analysed lymph nodes in neck dissection, is one of the variables that could supplement the existing TNM classification in order to better stratify patients and their needs for further ...
Ana Kvolik Pavić, Josip Butković, Vedran Zubčić, Zvonimir Popović, Dinko Leović   +4 more
doaj   +1 more source

Identification of Novel Tumor Microenvironment-Related Long Noncoding RNAs to Determine the Prognosis and Response to Immunotherapy of Hepatocellular Carcinoma Patients

Frontiers in Molecular Biosciences, 2021
Introduction: Hepatocellular carcinoma (HCC) is one of the most common malignant tumors with poor prognosis. The tumor microenvironment (TME) plays a vital role in HCC progression.
Shenglan Huang, Shenglan Huang, Jian Zhang, Jian Zhang, Xiaolan Lai, Lingling Zhuang, Lingling Zhuang, Jianbing Wu, Jianbing Wu   +8 more
doaj   +1 more source

Kaplan- Meier recovery estimate and smoothed hazard estimate of CKD among type two diabetic patients in western Amhara referral hospitals (n = 415).

, 2022
Kaplan- Meier recovery estimate and smoothed hazard estimate of CKD among type two diabetic patients in western Amhara referral hospitals (n = 415).
Wubet Worku Takele (10011247), Medina Abdela Ahmed (12003709), Yohannes Mulu Ferede (10675857)   +2 more
core   +1 more source