Results 221 to 230 of about 156,286 (266)

Is surgery with curative intent feasible in old and very old patients with non-small cell lung cancer? - Experience of a certified lung cancer center over one decade. [PDF]

Langenbecks Arch Surg
Zimmermann J, Walter J, Samm N, Damirov F, Reinmuth N, Kauffmann-Gerrero D, Hatz RA, Tufman A, Schneider CP.   +8 more
europepmc   +1 more source

The FOXC2‐LAMA4 Axis Orchestrates Vasculogenic Mimicry and Immunosuppressive Niche Formation to Drive Metastatic Cascade in Renal Cell Carcinoma

Advanced Science, EarlyView.
Advanced clear cell renal cell carcinoma metastasis is driven by a FOXC2+ tumor subpopulation. These cells execute vasculogenic mimicry for dissemination and secrete LAMA4. LAMA4 engages macrophage ITGA6, activating the STAT6/GATA3 axis to polarize macrophages into a pro‐metastatic, immunosuppressive phenotype.
Jiaxi Yao, Tong Xu, Chengyuan Wang, Chenyuan Wang, Junfeng Xie, Rui Zheng, Ke Wang, Xingzuo Jiang, Zewei Hu, Hongwei Jing, Lin Li, Tao Liu   +11 more
wiley   +1 more source

Implantable Cardioverter-Defibrillators in Children: A 14-Year Population-Based Study. [PDF]

J Arrhythm
Bjeloševič M, Olejník P, Tomko J, Chalupka M, Illíková V.   +4 more
europepmc   +1 more source

Cox-Snell residual graph, based on the Kaplan–Meier estimated survivor function, to test the overall adequacy of the cox proportional hazard model of time to PAD and its predictors of type 2 DM patients at FHCSH, 2023.

Dessalew Abelneh Woleli (20978345), Gebiyaw Wudie Tsegaye (8808815), Taye Abuhay (8585961), Abyot Terefe Teshome (20978348), Gebrie Getu Alemu (13876372)   +4 more
openalex   +1 more source

GNL3 Orchestrates AR Transcriptional Programs to Drive Castration‐Resistant Prostate Cancer and Immune Evasion

Advanced Science, EarlyView.
GNL3 is a novel AR coregulator with dual coactivator and corepressor functions in prostate cancer (PCa). Our study uncovers a previously unrecognized mechanism by which the AR transcriptional complex integrates oncogenic signaling and immune suppression.
Cuiting Zhang, Tin Long Cheong, Nitin Narwade, Dandan Dong, Mokan Deng, Zhengqiang Miao, Zhaoqiang Ding, Wenchao Li, Kate Man Kei Lei, Gong‐Hong Wei, Terence Chuen Wai Poon, Chu‐Xia Deng, Edwin Cheung   +12 more
wiley   +1 more source

Metabolic profiling of the TME uncovers the contrasting impacts of CKMT2 and PDE2A in CRC progression and therapeutic response. [PDF]

Front Pharmacol
Fu Y, Lai J, Huang K, Liu L, Liao G.
europepmc   +1 more source

Kaplan-Meier survival estimates of mortality.

Ting-Ju Kuo (21519771), Shih-Wei Huang (177920), Hui-Wen Lin (767574)   +2 more
openalex   +1 more source

Targeting the GPX4–FUNDC1 Interaction with Magnesium Lithospermate B Attenuates Sepsis‐Associated Lung Injury

Advanced Science, EarlyView.
The diagram depicts the endothelial‐protective mechanism of magnesium lithospermate B (MLB) in sepsis‐associated lung injury. MLB binds GPX4 at Gly79, disrupts its interaction with FUNDC1, prevents mitophagy‐mediated GPX4 degradation, restores mitophagic flux, reduces ROS, and limits ferroptosis.
Zhixi Li, Chang Liu, Zhaoxue Ma, Dongyou Zheng, Renkai Wang, Yongjing Yu, Guangmin Chen, Chenglong Li, Yue Bu, Hang Cao, Bing Zhang   +10 more
wiley   +1 more source

MLANA is a potential prognostic biomarker and correlated with immune infiltration in skin cutaneous melanoma. [PDF]

Clin Exp Med
Tang N, Lai X, Wen W, Wu Y, Xiong X.
europepmc   +1 more source

Kaplan–Meier analysis estimated the probability of treatment success categorised by the range of pre-BTXA esodeviation at near (a) and distance (b), as well as time from diagnosis to treatment (c).

Narisa Rattanalert (21445983), Teechaya Nonboonyawat (22238474), Supaporn Tengtrisorn (577973), Penny Singha (21445989), Orapan Aryasit (22238477), Juthamat Witthayaweerasak (12647329), Manupol Tangthongkum (22238480)   +6 more
openalex   +1 more source