Results 91 to 100 of about 5,941 (171)

Immune reconstitution inflammatory syndrome, human herpesvirus 8 viremia, and HIV-associated multicentric Castleman disease

International Journal of Infectious Diseases, 2016
Kaposi's sarcoma and multicentric Castleman Disease are HIV-related disease processes that are associated with human herpesvirus 8 (HHV-8) infection.
Marc O. Siegel, Sanaz Ghafouri, Ravi Ajmera, Gary L. Simon   +3 more
doaj   +1 more source

Cells of the Innate and Adaptive Immune Systems in Kaposi’s Sarcoma

Journal of Immunology Research, 2020
Kaposi’s sarcoma (KS) is an angioproliferative malignancy whose associated etiologic agent is the Kaposi’s sarcoma-associated herpesvirus (KSHV). KS is the most prevalent malignancy among HIV-infected individuals globally and is considered an AIDS ...
Owen Ngalamika, Sody Munsaka
doaj   +1 more source

Pharmacogenomic and structural analysis of constitutive G-protein coupled receptor activity [PDF]

, 2007
Premi a l'excel·lència investigadora. Àmbit de les Ciències de la Salut. 2008G-protein coupled receptors (GPCRs) respond to a chemically diverse plethora of signal transduction molecules.
Aldo Jongejan, Alewijnse AE, Ariens EJ, Brown EM, Cesarman E, Chen F, Clark AJ, Clark AJ, Cobbs CS, Furchgott RF, Furchgott RF, Garcia-Borron JC, Henk Timmerman, Henry F. Vischer, Leonardo Pardo, Mannstadt M, Martine J. Smit, Murphy PM, Nauta WT, Rauser L, Reiter EO, Remko A. Bakker, Rob Leurs, Rossier O, Samama P, Scheer A, Stephenson RP, Tabs S, Weiner DM, Wieland K   +29 more
core   +3 more sources

Neuroinflammation as a result of non‐neurotropic herpesvirus infection

Immunology &Cell Biology, Volume 104, Issue 5, Page 443-451, May‐June 2026.
Atypical memory B cells (ABCs) might stimulate autoreactive T cells to cause neuroinflammation and CNS myeloid cell activation during MS. Abstract The non‐neurotropic Epstein Barr virus (EBV) has been suggested to initiate the prodromal phase of multiple sclerosis (MS), often years before the first clinical symptoms. This review discusses mechanisms by
Christian Münz
wiley   +1 more source

Development of KSHV vaccine platforms and chimeric MHV68-K-K8.1 glycoprotein for evaluating the in vivo immunogenicity and efficacy of KSHV vaccine candidates

mBio
Kaposi’s sarcoma-associated herpesvirus (KSHV)/human herpesvirus 8 is an etiological agent of Kaposi’s Sarcoma, multicentric Castleman’s disease, and primary effusion lymphoma. Considering the high seroprevalence reaching up to 80% in sub-Saharan Africa,
Wan-Shan Yang, Dokyun Kim, Soowon Kang, Chih-Jen Lai, Inho Cha, Pei-Ching Chang, Jae U. Jung   +6 more
doaj   +1 more source

Kaposi's sarcoma-associated herpesvirus (KSHV) vIL-6 promotes cell proliferation and migration by upregulating DNMT1 via STAT3 activation.

PLoS ONE, 2014
Kaposi's sarcoma-associated herpesvirus (KSHV) is etiologically associated with Kaposi's sarcoma (KS), the most common AIDS-related malignancy. KSHV vIL-6 promotes KS development, but the exact mechanisms remain unclear. Here, we reported that KSHV vIL-6
Jing Wu, Yuqiao Xu, Dongping Mo, Peijun Huang, Ruihong Sun, Lei Huang, Shiyang Pan, Jian Xu   +7 more
doaj   +1 more source

Identification of Quality Markers in Viola kunawaresis Royel Using HPLC Fingerprints, Chemometric Analysis, and Network Pharmacology

Biomedical Chromatography, Volume 40, Issue 4, April 2026.
ABSTRACT Violae tianshanicae herba (VTH), a widely used crude drug in Uyghur medicine in China, is renowned for its immunomodulatory, anti‐inflammatory, antibacterial, antiviral, and antidiabetic activities, with notable efficacy in treating asthma. However, systematic research on its quality markers (Q‐markers) remains limited, underscoring the need ...
Haifeng Liu, Rongmei Zhao, Hong Xu, Tabusi Manaer, Le Pan, Lu Jin, Amatjan Ayupbek   +6 more
wiley   +1 more source

Novel Virus Related to Kaposi’s Sarcoma–Associated Herpesvirus from Colobus Monkey

Emerging Infectious Diseases, 2019
We determined the complete genome sequence of a virus isolated from a mantled guereza that died of primary effusion lymphoma. The virus is closely related to Kaposi’s sarcoma–associated herpesvirus (KSHV) but lacks some genes implicated in KSHV ...
Akshay Dhingra, Tina Ganzenmueller, Elias Hage, Nicolás M. Suárez, Kerstin Mätz-Rensing, Dimitri Widmer, Stefan Pöhlmann, Andrew J. Davison, Thomas F. Schulz, Artur Kaul   +9 more
doaj   +1 more source

KSHV gB associated RGD interactions promote attachment of cells by inhibiting the potential migratory signals induced by the disintegrin-like domain [PDF]

, 2016
Background: Kaposi's sarcoma-associated herpesvirus (KSHV) glycoprotein B (gB) is not only expressed on the envelope of mature virions but also on the surfaces of cells undergoing lytic replication.
A Georgoulis, A Oppelt, BT Ning, C Bandyopadhyay, C Sun, D Lu, D Murray, DA Higuchi, DG Menter, E Rossi, ES Chhabra, F Angius, F Nakamura, FZ Wang, H Abe, H Doppler, HH Krishnan, HM Verheul, Hosni A. M. Hussein, HS Selistre-de-Araujo, I Limam, J Cau, J Chen, J Kim, J Lartigue de, J Li, JJ Calvete, JW Lee, K Eto, K Moissoglu, KJ Sepp, L Zhang, Lia R. Walker, LR Walker, M Chen, M May, M Onishi, N Sharma-Walia, NL Malinin, OF Dyson, OF Dyson, OF Dyson, PP Naranatt, R Karlsson, R Keil, RS Piotrowicz, S Abraham, SA Morad, SA Rezaee, Shaw M. Akula, SM Akula, SM Akula, SM Akula, ST Ong, T Geback, Y Kikkawa   +55 more
core   +1 more source

Iatrogenic Kaposi Sarcoma in an HIV‐Negative Patient With Immune Thrombocytopenic Purpura Treated With Rituximab and Corticosteroids: A Fatal Extracutaneous Presentation

Cancer Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background Kaposi sarcoma (KS) is a Kaposi sarcoma, an Human herpesvirus 8 infection–associated endothelial neoplasm that typically arises in the setting of immune deficiency. Iatrogenic KS in HIV‐negative patients treated for Immune thrombocytopenic purpura is rare, particularly in those receiving immunosuppressive therapies such as rituximab
Rami Khader, Mohammed Yousef Awad, Ayman Zebda, Mousa Almasalma, Ro'a Draidi, Esraa Elhakim, Mohammad Bdair, Ameed Khader   +7 more
wiley   +1 more source