Structures of Epstein-Barr virus and Kaposi's sarcoma-associated herpesvirus virions reveal species-specific tegument and envelope features. [PDF]
Zhen J +9 more
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IFI16 recruits HDAC1 and HDAC2 to deacetylate the Kaposi's sarcoma-associated herpesvirus (KSHV) latency-associated nuclear antigen (LANA), facilitating latency. [PDF]
Ghosh A, Britto J, Chandran B, Roy A.
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Kaposi's sarcoma-associated herpesvirus terminal repeat regulates inducible lytic gene promoters. [PDF]
Izumiya Y +6 more
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Kaposi's sarcoma-associated herpesvirus (KSHV) LANA prevents KSHV episomes from degradation. [PDF]
Nakajima K-i +3 more
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Kaposi's sarcoma-associated herpesvirus and Kaposi's sarcoma
Microbes and Infection, 2000Kaposi's sarcoma-associated herpesvirus (KSHV) is present in all epidemiologic forms of Kaposi's sarcoma (KS). The KSHV genome contains several open reading frames which are potentially implicated in the development of KS. Some are unique to KSHV; others are homologous to cellular genes.
H, Gruffat, A, Sergeant, E, Manet
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Biology of Kaposi's sarcoma-associated herpesvirus
Frontiers in Bioscience, 2005Kaposi's sarcoma-associated herpesvirus (KSHV) or human herpesvirus-8 (HHV-8) is a newly identified herpesvirus. KSHV is an important pathogen capable of causing disease that affects all age groups worldwide. KSHV is etiologically associated with all forms of Kaposi's sarcoma (KS), body cavity lymphomas, and multicentric Castleman disease (MCD).
Benjaman A, Bryan +3 more
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Kaposi's sarcoma‐associated herpesvirus and extracellular vesicles
Journal of Medical Virology, 2021AbstractKaposi's sarcoma‐associated herpesvirus (KSHV) represents the etiological agent for several human malignancies, including Kaposi's Sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman's disease (MCD), which develop mainly in immunocompromised patients.
Lindsey Barrett +3 more
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Kaposi's Sarcoma-Associated Herpesvirus
1998Kaposi's sarcoma (KS) is a vascular tumor predominantly found in the immunosuppressed. Epidemiologic studies suggest that an infective agent is the etiologic culprit. Kaposi's sarcoma-associated herpesvirus (KSHV), or human herpesvirus-8 (HHV-8), is a gamma human herpesvirus present in all epidemiologic forms of KS and also in a rare type of a B cell ...
C, Boshoff, R A, Weiss
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Molecular biology of Kaposi's sarcoma-associated herpesvirus
Frontiers in Bioscience, 2002Over the past twenty odd years, kaposi's sarcoma has launched from being a rare pathological curiosity to a significant public health concern. This massive increase in incidence, concurrent with the aids epidemic, has sparked a tremendous amount of interest in uncovering the etiopathogenesis of this disease.
Murray A, Cotter, Erle S, Robertson
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Kaposi Sarcoma–Associated Herpesvirus/Human Herpesvirus 8 and Kaposi Sarcoma
Advances in Dental Research, 2011Kaposi sarcoma-associated herpesvirus (KSHV) was discovered in 1994 and is now known to be a necessary but not sufficient causative agent of Kaposi sarcoma. While KSHV is likely also the causative agent of primary effusion lymphoma and multicentric Castleman’s disease, its causal role has been refuted in the case of multiple myeloma, sarcoidosis ...
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