Results 11 to 20 of about 19,279 (198)

Toward Anti-Herpesviral PROTACs: Assessing the Challenges for Targeted Protein Degradation on the Example of Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen. [PDF]

ChemMedChem
It is attempted to employ proteolysis‐targeting chimeras‐based targeted protein degradation to the viral protein “Latency‐associated Nuclear Antigen” from Kaposi's sarcoma‐associated herpesvirus. While ternary complex formation is detected via native mass spectrometry, protein degradation is not observed, presumably due to insufficient permeability ...
Berwanger A, Stein SC, Brandner S, Kany AM, Heinz S, Loretz B, Lehr CM, Hirsch AKH, Lermyte F, Schulz TF, Empting M.   +10 more
europepmc   +2 more sources

A case report of the rapid dissemination of Kaposi’s sarcoma in a patient with HIV

African Journal of Primary Health Care & Family Medicine, 2013
Introduction: Kaposi’s sarcoma is the most common HIV-associated neoplastic disease. In most cases it starts on the skin and later spreads to other visceral organs.
Indiran Govender, Mogakgomo H. Motswaledi, Langalibalele H. Mabuza   +2 more
doaj   +1 more source

Consensus of the Brazilian Society of Infectious Diseases and Brazilian Society of Clinical Oncology on the management and treatment of Kaposi's sarcoma

Brazilian Journal of Infectious Diseases, 2014
Kaposi's sarcoma is a multifocal vascular lesion of low-grade potential that is most often present in mucocutaneous sites and usually also affects lymph nodes and visceral organs.
Érico Arruda, Alexandre Andrade dos Anjos Jacome, Ana Luiza de Castro Conde Toscano, Anderson Arantes Silvestrini, André Santa Bárbara Rêgo, Evanius Garcia Wiermann, Geraldo Felicio da Cunha, Jr., Heloisa Ramos Lacerda de Melo, Karen Mirna Loro Morejón, Luciano Zubaran Goldani, Luiz Carlos Pereira, Jr., Mariliza Henrique Silva, Mauro Sergio Treistman, Mônica Cristina Toledo Pereira, Patricia Maria Bezerra Xavier Romero, Rafael Aron Schmerling, Rodrigo Antonio Vieira Guedes, Veridiana Pires de Camargo   +17 more
doaj   +1 more source

Pulmonary Kaposi's sarcoma—an atypical clinical presentation

International Journal of Infectious Diseases, 2022
HIV-associated Kaposi's sarcoma is an angioproliferative neoplasia caused by infection with human herpesvirus 8. It typically presents with mucocutaneous involvement. Pulmonary Kaposi's sarcoma is rare, and an uncommon form of initial presentation of the
Ana Luísa Ramos, Joana Granado, Ana Isabel Calderón, Sandra André, Fernando Nogueira   +4 more
doaj   +1 more source

Dermatomyositis with Kaposi’s Sarcoma in a Patient without Human Immunodeficiency Virus-1 Infection

Canadian Journal of Gastroenterology, 1991
The first case of dermatomyositis complicating cutaneous and visceral Kaposi’s sarcoma is presented in a 75-year-old man without human immunodeficiency virus infection.
Dana Liang, Andrew Szilagyi, Robin C Billick, Herbert Srolovitz, Ricardo Bullen   +4 more
doaj   +1 more source

Primary Research: Short Communication: Evidence Supporting Rare AIDS-Kaposi's Sarcoma Metastasis In Keeping With Their Vascular Endothelial Evolution

Cancer Cell International, 2002
Background It is postulated that the unusual manifestations of Kaposis's sarcoma cells in nonendothelial brain tissues and on eyeballs in advanced acquired immune deficiency syndrome (AIDS) cases are metastasized AIDS-Kaposi's sarcoma cells arising from ...
Mazumder Amitabha, Rahman Mahruf U
doaj   +1 more source

Does the knowledge of the human immunodeficiency virus serostatus influence the clinical diagnostic proficiency of Kaposi's sarcoma?

South African Family Practice, 2013
Objectives: Kaposi's sarcoma is an acquired immunodeficiency syndrome (AIDS)-defining illness. A spectrum of non- Kaposi's sarcoma clinical and histopathological mimickers contributes to the potential over- or underdiagnosis of Kaposi's sarcoma.
L.J. van Bogaert
doaj   +1 more source

EBV+ and Kaposi's Sarcoma Herpesvirus-Associated Multicentric Castleman Disease in a Patient With HIV Infection: A Case Report. [PDF]

Case Rep Infect Dis
Multicentric Castleman disease is a rare proliferative disease of lymphoid tissue. It has rarely been reported in Asian countries, particularly in HIV‐positive patients. Here, we report a case of Kaposi’s sarcoma herpesvirus‐associated Multicentric Castleman disease (KSHV‐MCD).
Huang MY, Li Z, Zhang W, Chen HY, Liu J, Li CX.   +5 more
europepmc   +2 more sources

Molecularly targeted therapy for Kaposi's sarcoma in a kidney transplant patient: case report, "what worked and what did not"

BMC Nephrology, 2007
Background Imatinib is a tyrosine-kinase inhibitor; for which there is limited information regarding its effects on AIDS Kaposi's sarcoma and none in patients with transplant-associated Kaposi's sarcoma.
Correa-Rotter Ricardo, Zinser Juan W, Volkow Patricia   +2 more
doaj   +1 more source

Early initiation of fast‐track care for persons living with HIV initiating dolutegravir‐based regimens during a period of severe civil unrest in Port‐au‐Prince, Haiti: a pilot randomized trial

Journal of the International AIDS Society
Introduction Differentiated service delivery (DSD) models have been widely implemented for patients in stable HIV care. However, DSD has rarely been offered to newly diagnosed patients.
Jean Bernard Marc, Samuel Pierre, Othnia Ducatel, Fabienne Homeus, Abigail Zion, Vanessa R. Rivera, Nancy Dorvil, Patrice Severe, Colette Guiteau, Vanessa Rouzier, Ingrid T. Katz, Carl Frederic Duchatelier, Guyrlaine Pierre Louis Forestal, Josette Jean, Guirlaine Bernadin, Emelyne Droit Dumont, Rose Cardelle B. Riche, Jean William Pape, Serena P. Koenig   +18 more
doaj   +1 more source