Results 51 to 60 of about 209,889 (303)

Kaposi's sarcoma-associated herpesvirus oncoprotein K13 protects against B cell receptor induced growth arrest and apoptosis through NF-κB activation [PDF]

, 2013
Kaposi's sarcoma-associated herpesvirus (KSHV) has been linked to the development of Kaposi's sarcoma, primary effusion lymphoma and multicentric Castleman's disease (MCD). We have characterized the role of KSHV-encoded viral FLICE inhibitory protein K13
Ahmad, B. Tolani, Ballon, Benhamou, Bower, Bren, C. Graham, Chang, Chaudhary, Chugh, Delmore, Dong, Du, Dupin, Dupin, Eeva, Eeva, Field, Gerondakis, Guasparri, H. Matta, H. Yi, Hassman, Herzog, Lee, Liu, Madureira, Matta, Matta, Matta, Matta, Mineva, Nador, Niiro, P. M. Chaudhary, Parravicini, Punj, Schauer, Soulier, Sun, Sun, Sun, Thome, Vrzalikova, Waterston, Wu, Wu, Wu, Y. Suo, Y. Yang, Yang, Yang, Young, Zhao   +53 more
core   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Disseminated Kaposi Sarcoma

Clinical, Cosmetic and Investigational Dermatology, 2022
AIDS-associated Kaposi sarcoma (KS) is the most common HIV-associated neoplasm. Disseminated Kaposi sarcoma became rare with the application of antiretroviral therapy. Oral AIDS-associated KS has prognostic relevance, indicating higher mortality than those with cutaneous lesions only.
Ma,Jin-Yuan, Liu,Jia-Wei
openaire   +3 more sources

Effectiveness of community‐based hypertension management on hypertension in the urban slums of Haiti: A mixed methods study

The Journal of Clinical Hypertension
Hypertension is a leading contributor to mortality in low‐middle income countries including Haiti, yet only 13% achieve blood pressure (BP) control.
Reichling St Sauveur, Rodney Sufra, Marie Christine Jean Pierre, Vanessa Rouzier, Fabiola Preval, Serfine Exantus, Mirline Jean, Josette Jean, Guyrlaine Pierre‐Louise Forestal, Obed Fleurijean, Nour Mourra, Anju Ogyu, Rodolphe Malebranche, Jean Pierre Brisma, Marie M. Deschamps, Jean W. Pape, Radhika Sundararajan, Margaret L. McNairy, Lily D. Yan   +18 more
doaj   +1 more source

AIDS‐associated Kaposi's sarcoma is linked to advanced disease and high mortality in a primary care HIV programme in South Africa

Journal of the International AIDS Society, 2010
Background AIDS‐associated Kaposi's sarcoma is an important, life‐threatening opportunistic infection among people living with HIV/AIDS in resource‐limited settings.
Kathryn M Chu, Gcina Mahlangeni, Sarah Swannet, Nathan P Ford, Andrew Boulle, Gilles Van Cutsem   +5 more
doaj   +1 more source

Immune reconstitution inflammatory syndrome associated with acquired immunodeficiency syndrome-related gastrointestinal limited Kaposi's sarcoma presenting as acute intestinal obstruction: a case report

Journal of Medical Case Reports, 2011
Introduction Immune reconstitution inflammatory syndrome during anti-retroviral treatment of acquired immunodeficiency syndrome (AIDS) -associated gastrointestinal Kaposi's sarcoma has rarely been reported.
Pathak Hari, Shrivastav Ankit, Pal Jyotirmoy, Sarkar Dipendra   +3 more
doaj   +1 more source

Kaposi’s sarcoma associated with chronic myeloid leukemia and imatinib mesylate therapy

Clinical Case Reports, 2022
Kaposi's sarcoma is associated with immunosuppression and human herpesvirus 8 infection, while rarely described in myeloid malignancies. Here, we illustrate a rare case of chronic myeloid leukemia treated with imatinib, a tyrosine kinase inhibitor, who ...
Matteo D’Addona, Luca Pezzullo, Valentina Giudice, Bianca Serio, Carlo Baldi, Pio Zeppa, Carmine Selleri   +6 more
doaj   +1 more source

Deregulation of HDAC5 by Viral Interferon Regulatory Factor 3 Plays an Essential Role in Kaposi's Sarcoma-Associated Herpesvirus-Induced Lymphangiogenesis. [PDF]

, 2018
Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent for Kaposi's sarcoma (KS), which is one of the most common HIV-associated neoplasms.
Fan Li, Grace M. Aldrovandi, Hye Ryun Yu, Hye-Ra Lee, Jae U. Jung, Peter Palese, Pinghui Feng, Shou-Jiang Gao, Un Yung Choi, Young-Kwon Hong   +9 more
core   +3 more sources

Discovery of a Baloxavir‐Inspired Endonuclease Inhibitor That Prevents Herpes Simplex Virus 1 Replication in Cell Culture and In Vivo

Advanced Science, EarlyView.
Current herpesvirus treatments targeting the viral DNA polymerase are limited by toxicities and drug resistance. Novel compounds inhibiting the nuclease activity of the herpes simplex virus 1 (HSV‐1) terminase complex, required for viral genome packaging, have been identified.
Sabina Andreu, Kai Tang, Jiahui Zhou, Gabriel Pino‐Peco, Nerea López‐Carrobles, Raquel Bello‐Morales, Daniel Galdo‐Torres, Lina Zhang, Federico Gago, José Antonio López‐Guerrero, Xinyong Liu, Peng Zhan, Luis Menéndez‐Arias   +12 more
wiley   +1 more source

Kaposi's sarcoma in two primary liver allograft recipients occurring under FK506 immunosuppression [PDF]

, 1993
Of 1463 liver allograft recipients receiving the combination of FK506 and steroids as their primary immunosuppressive regimen, 2 patients developed Kaposi's sarcoma.
Bronsther, O, Fung, JJ, Kadry, Z, Randhawa, P, Starzl, TE, Van Thiel, DH   +5 more
core