Results 201 to 210 of about 147,278 (285)

Risk of Transformation to Acute Myeloid Leukaemia and Myelodysplastic Syndromes in Patients With Myeloproliferative Neoplasms Over Attained Age and Time Since Diagnosis: A Nationwide Cohort Study

European Journal of Haematology, EarlyView.
ABSTRACT Background Individuals with polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF) face transformation risks to acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). While older age is linked to increased risk, it remains unclear whether risk increases with age or with disease duration.
Nurgul Batyrbekova, Anna Ravn Landtblom, Malin Hultcrantz, Robert Szulkin, Paul W. Dickman, Therese M.‐L. Andersson   +5 more
wiley   +1 more source

Fertility issues and pregnancy outcomes in females with partial X-chromosome deletions: a retrospective observational cohort study. [PDF]

BMC Pregnancy Childbirth
Li XT, Dai Y, Chen JY, Cai MJ, Yao XM, Ge YS.   +5 more
europepmc   +1 more source

ABSTRACTS

Precision Radiation Oncology, EarlyView.
wiley   +1 more source

Acalabrutinib in Chronic Lymphocytic Leukemia: Pharmacology and Emerging Clinical Perspectives

European Journal of Haematology, EarlyView.
ABSTRACT Acalabrutinib, a second‐generation Bruton's tyrosine kinase inhibitor (BTKi), is characterized by enhanced specificity and selectivity for BTK with minimal off‐target effects, offering a significant evolution in the treatment of chronic lymphocytic leukemia (CLL). Its mechanism of action, a covalent binding to Cys481 within the BTK active site,
Gianluca Gaidano, Romano Danesi
wiley   +1 more source

Comparative Chromosomal Mapping of the 18S rDNA Loci in True Bugs: The First Data for 13 Genera of the Infraorders Cimicomorpha and Pentatomomorpha (Hemiptera, Heteroptera). [PDF]

Genes (Basel)
Golub NV, Anokhin BA, Grozeva S, Kuznetsova VG.   +3 more
europepmc   +1 more source

Polycythaemic panmyelosis in chronic myeloid leukaemia

British Journal of Haematology, EarlyView.
George Mason, Ameya Hanamshet, Sewon Kim, Nisha Singh, Kirsten McIlroy, Matthew Greenwood   +5 more
wiley   +1 more source

Ph‐Negative Acute Lymphoblastic Leukemia in the Older Adults: Biology, Therapeutic Strategies and Unmet Needs

European Journal of Haematology, EarlyView.
ABSTRACT Acute lymphoblastic leukaemia (ALL) in older adults represents a growing clinical challenge, driven by an ageing population, adverse disease biology, and reduced tolerance to intensive chemotherapy. Although pediatric‐inspired regimens have improved outcomes in younger adults with Philadelphia chromosome (Ph)‐negative ALL, survival in older ...
Antonella Bruzzese, Ernesto Vigna, Enrica Antonia Martino, Santino Caserta, Francesco Mendicino, Maria Eugenia Alvaro, Caterina Labanca, Eugenio Lucia, Virginia Olivito, Marco Fiorillo, Nicola Amodio, Fortunato Morabito, Massimo Gentile   +12 more
wiley   +1 more source

Case Report: Prenatal diagnosis of a rare complex fetal karyotype 47,U,t(10;13)(p15;q22)mat,+der(13)t(10;13)dmat resulting from 3:1 meiotic segregation of a maternal balanced translocation. [PDF]

Front Reprod Health
Deng GS, Zhang DH, Lai YQ, Song JJ, Pan JJ, Liang XF, Lu YH, Ning SS, Li WC, Li X, Chen YY, Li DR, Li LL, Liang YN.   +13 more
europepmc   +1 more source

Long‐Term Clinical and Molecular Dynamics in Hypoplastic Myelodysplastic Neoplasia Treated With Immunosuppressive Therapy

European Journal of Haematology, EarlyView.
ABSTRACT Myelodysplastic neoplasia (MDS) comprises heterogeneous clonal hematologic disorders characterized by peripheral cytopenia, bone marrow dysplasia, and a risk of leukemic transformation. A hypoplastic variant (MDS‐h) shares features with aplastic anemia and responds to immunosuppressive therapy (IST).
Hannes Treiber, Christina Ganster, Katayoon Shirneshan, Katharina Rittscher, Elzbieta Brzuszkiewicz, Justin Hasenkamp, Wolfram Jung, Gerald Wulf, Detlef Haase   +8 more
wiley   +1 more source