Results 91 to 100 of about 2,554 (202)

An experimental animal model of Kashin-Beck disease. [PDF]

open access: yesAnnals of the Rheumatic Diseases, 1989
Twelve young macaque monkeys were fed with grain and water from areas actively endemic or non-endemic for Kashin-Beck disease. Both dietary grain and water from geographical areas endemic for Kashin-Beck disease induced a sequence of pathological changes in the growth plates and articular cartilage and biochemical changes in the serum and urine of ...
G Q, Zhang, J X, Liu
openaire   +2 more sources

Comparison of microRNA expression profiles of Kashin-Beck disease, osteoarthritis and rheumatoid arthritis

open access: yesScientific Reports, 2017
Kashin-Beck disease (KBD) is a chronic osteochondropathy with unclear pathogeny. In this study, we compared the microRNA expression profiles of 16 KBD patients, 16 osteoarthritis (OA) patients and 16 rheumatoid arthritis (RA) patients and 16 healthy ...
Wenhong Wu   +6 more
doaj   +1 more source

Association study of polymorphisms in selenoprotein genes and Kashin-Beck disease and serum selenium/iodine concentration in a Tibetan population.

open access: yesPLoS ONE, 2013
BackgroundKashin-Beck disease is a kind of degenerative osteoarthropathy. Genetic factors may play an important role in the pathogenesis of KBD.ObjectiveTo investigate the association of the selenoprotein genes GPX1 (rs1050450, rs1800668, and rs3811699),
Lulin Huang   +11 more
doaj   +1 more source

Theranostic scope of monometallic selenium and titanium dioxide nanoparticles in biomedicine: A review

open access: yesHealth Care Science, Volume 3, Issue 4, Page 215-231, August 2024.
The nanoparticles (NPs) of metals and metal oxides constitute significant components of technology in terms of monometallic NPs (MNPs). Throughout the last 10 years, the most fascinating and in‐depth uses of NPs have been found in the biomedical field, which has demonstrated the therapeutic potential of these particles. Significant strides were made in
Shwetha B. Nagarajan   +2 more
wiley   +1 more source

The protective role of autophagy in experimental osteoarthritis, and the therapeutic effects of Torin 1 on osteoarthritis by activating autophagy [PDF]

open access: yes, 2016
BACKGROUND: Recent studies have shown that autophagy was associated with the development of osteoarthritis (OA), the purpose of this research was to determine the exact role of autophagy in OA and investigate effective therapeutic drugs to inhibit the ...
Ai Guo, Hai Meng, Ni-Tao Cheng
core   +1 more source

A comprehensive review on nutritional interventions and nutritive elements: Strengthening immunity for effective defense mechanism during pandemic

open access: yesFood Science &Nutrition, Volume 12, Issue 7, Page 4534-4545, July 2024.
The phase of pandemic has brought attention to how important a healthy immune system is in preventing infectious diseases. In this in‐depth review, the process that how nutritional interventions and fundamental nutrients affect immune function has been mentioned with the goal of enhancing the body's natural defenses against viral infections.
Sonal Prasad   +5 more
wiley   +1 more source

Genetic variants in the ITPR2 gene are associated with Kashin‐Beck Disease in Tibetan

open access: yesMolecular Genetics & Genomic Medicine, 2019
Background Kashin‐Beck Disease (KBD) is a chronic, endemic osteoarthropathy. Inositol 1,4,5‐triphosphate receptor type 2 (ITPR2) gene is involved in chondrocytes.
Xue He   +7 more
doaj   +1 more source

Ajo selenizado: ¿un alimento funcional futuro o actual? [PDF]

open access: yes, 2012
In the last years, functional foods have awakened consumer, scientific and business interest. A commonly found vegetable in such kind of foods includes garlic (Allium sativum).
Escudero, Leticia B.   +4 more
core  

AZI23'UTR Is a New SLC6A3 Downregulator Associated with an Epistatic Protection Against Substance Use Disorders [PDF]

open access: yes, 2017
Regulated activity of SLC6A3, which encodes the human dopamine transporter (DAT), contributes to diseases such as substance abuse disorders (SUDs); however, the exact transcription mechanism remains poorly understood.
Bell, Richard L.   +9 more
core   +2 more sources

Selenosugar, selenopolysaccharide, and putative selenoflavonoid in plants

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 23, Issue 3, May 2024.
Abstract Selenium (Se) is a naturally occurring essential micronutrient that is required for human health. Selenium supports cellular antioxidant defense and possesses bioeffects such as anti‐inflammation, anti‐cancer, anti‐diabetic, and cardiovascular and liver protective effects arising from Se‐enhanced cellular antioxidant activity.
Ziqi Qi, Alex Duan, Ken Ng
wiley   +1 more source

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