Results 71 to 80 of about 2,554 (202)
Selenium Nanoparticles in Cancer Therapy: Unveiling Cytotoxic Mechanisms and Therapeutic Potential
Cancer Reports, Volume 8, Issue 6, June 2025.ABSTRACT Background Cancer represents a complex group of diseases characterized by abnormal cell proliferation, invasion, and metastasis. These features pose significant challenges to conventional therapeutic approaches, necessitating the development of more targeted and effective treatment strategies.
Sumaira Anjum +6 more
wiley +1 more source
Selenoprotein M is expressed during bone development [PDF]
, 2013 25 selenoproteins that contain selenium, incorporated as selenocysteine (Sec), have been identified to date. Selenoprotein M (SELM) is one of seven endoplasmic reticulum (ER)-resident, Sec-containing proteins that may be involved in posttranslational ...
Bösl, Michael +4 more
core
Kashin-Beck disease and drinking water in Central Tibet [PDF]
International Orthopaedics, 2001 A cross-sectional survey was carried out in order to study the relationship between Kashin-Beck disease and drinking water. The average volume of the water containers was larger in families unaffected by the disease. Organic material was measured by ultraviolet (UV) spectroscopy. The UV absorbency was significantly lower in drinking water of unaffected
M, La Grange +4 more
openaire +2 more sources
LRP1 Mediates Endocytosis Activity and Is a Potential Therapeutic Target in Osteoarthritis
Orthopaedic Surgery, Volume 17, Issue 6, Page 1604-1619, June 2025.(A) The risk factors associated with OA development. (B) Exosomes derived from TNF‐α stimulate upregulation of LRP1 levels in IPFP‐MSC‐derived exosomes, thereby exerting chondroprotective effects. (C) The regulation of endocytosis by LRP1, which impacts chondrocyte proliferation and apoptosis.
Yuangang Wu +8 more
wiley +1 more source
Discovery and genotyping of structural variation from long-read haploid genome sequence data [PDF]
, 2016 In an effort to more fully understand the full spectrum of human genetic variation, we generated deep single-molecule, real-time (SMRT) sequencing data from two haploid human genomes.
Boitano, Matthew +15 more
core +2 more sources
Research Progress of Drinking Water and Trace Elements in KBD Area [PDF]
, 2023 Kaschin-beck disease (KBD) is an endemic, chronic, and deformable osteochondral disease characterized by multiple degenerations and deep cell necrosis of epiphysis, epiphysis, and articular cartilage.
Huang, Tianjiao, Kou, Jiushe
core +2 more sources
Frontiers in Genetics, 2022 Background and aims: Kashin-Beck disease (KBD) is a unique endemic osteochondropathy with unclear pathogenesis in China. T-2 toxin exposure has been identified as a significant risk factor of KBD.
Yujie Ning +16 more
doaj +1 more source
Earth's Future, Volume 13, Issue 2, February 2025.Abstract Selenium is an essential micronutrient, yet its deficiency poses severe health risks, including Kashin‐Beck disease, a debilitating disorder endemic to selenium‐deficient regions like Tibet. Despite the known risks, the extent and drivers of selenium deficiency in Tibetan populations remain poorly characterized.
Yi Yang +4 more
wiley +1 more source
A note on the effectiveness of selenium supplementation of Irish-grown Allium crops. [PDF]
, 2014 peer-reviewedThis study is funded by the Department of Agriculture and Food through the Network and Team Building Initiative of the Food Institutional Research Measure (FIRM Reference Number 06/NITARFC6).Onions and other Allium crops contain high levels ...
Brunton, Nigel +5 more
core
Kazan medical journal, 1927 Endemic arthritis or the so-called "Urovskaya disease" was first discovered by Dr. Kashin 75 years ago among residents of the Ura river valley (in Transbaikalia), hence the name "Urovskaya disease". The author calls this peculiar disease ache disease. With regard to etiology, Dr.
openaire +1 more source