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Total Synthesis of Kasugamycin

Organic Letters
We present an efficient synthetic pathway for kasugamycin, an aminoglycoside antibiotic, utilizing naturally derived carbohydrates as starting materials. This synthesis effectively addresses stereochemical complexities by employing the selective reduction of d-fucal, which generates a crucial 3-deoxyglycal intermediate.
Ting Li   +4 more
openaire   +2 more sources

Evaluation of kasugamycin as a chiral selector in capillary electrophoresis

The Analyst, 2023
This work describes the chiral separation performances of kasugamycin as a new chiral selector in capillary electrophoresis for six pairs of stereoisomers.
Chunyan Zhang   +3 more
openaire   +2 more sources

Mechanism of Kasugamycin Resistance in Escherichia coli

Nature New Biology, 1972
Strains of Escherichia coli are resistant to the antibiotic kasugamycin due to the partial non-methylation of 16S ribosomal RNA. An RNA methylase activity, absent from resistant strains, is shown here to methylate in vitro the 16S RNA of resistant as well as sensitive strains.
T L, Helser, J E, Davies, J E, Dahlberg
openaire   +2 more sources

The total synthesis of kasugamycin

Journal of the American Chemical Society, 1968
Y, Suhara   +4 more
openaire   +2 more sources

Total synthesis of kasugamycin

Journal of the American Chemical Society, 1972
Y. Suhara   +5 more
openaire   +1 more source

Dissipation and dietary risk assessment of kasugamycin and saisentong in Chinese cabbage

Environmental Science and Pollution Research, 2020
Guofeng Chen, Xiaobo Zhang
exaly  

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