Results 31 to 40 of about 1,185 (155)

Kasugamycin potentiates rifampicin and limits emergence of resistance in Mycobacterium tuberculosis by specifically decreasing mycobacterial mistranslation

open access: yeseLife, 2018
Most bacteria use an indirect pathway to generate aminoacylated glutamine and/or asparagine tRNAs. Clinical isolates of Mycobacterium tuberculosis with increased rates of error in gene translation (mistranslation) involving the indirect tRNA ...
Swarnava Chaudhuri   +15 more
doaj   +1 more source

Impact of Soil Disinfestation on Fungal and Bacterial Communities in Soil With Cucumber Cultivation

open access: yesFrontiers in Microbiology, 2021
Soil treatment with disinfectants has been used for controlling soilborne phytopathogens. Besides suppressing specific pathogens, how these disinfectants impact soil health, especially soil microbial communities, is yet to be systemically determined. The
Yan Wang   +5 more
doaj   +1 more source

Effect of Kasugamycin on Fire Blight during the Flowering Stage of Apple in Korea [PDF]

open access: yesResearch in Plant Disease
Since fire blight was first discovered in Korea in 2015 on pears and apples, the agrochemicals containing streptomycin, oxolinic acid, and oxytetracycline as the main agents have been used as fire blight control agents. Since these antibiotics can easily
Hyeonheui Ham   +5 more
doaj   +1 more source

Development of an Analytical Method for Kasugamycin Residue in Herbal Medicine, Achyranthes japonica Nakai

open access: yesIndonesian Journal of Chemistry, 2022
This study developed a suitable analytical method for kasugamycin residues in Achyranthes japonica using LC/MS/MS equipped with an amide column for polar substances. Extraction and cleanup processes were done at pH 4.5–5.
Jeong Yoon Choi   +4 more
doaj   +1 more source

In Vitro Antibacterial Activity of Kasugamycin [PDF]

open access: yesApplied Microbiology, 1967
Kasugamycin is an aminoglycosidic antibiotic which was initially reported as being of potential use against Pseudomonas . Our evaluation of this antibiotic does not confirm this expectation. The median minimal inhibitory concentration (MIC) of the Pseudomonas strains tested was 250 μg/ml and ...
openaire   +2 more sources

Blockers of the SARS-CoV-2 3a Channel Identified by Targeted Drug Repurposing

open access: yesViruses, 2021
The etiological agent of the COVID-19 pandemic is SARS-CoV-2. As a member of the Coronaviridae, the enveloped pathogen has several membrane proteins, of which two, E and 3a, were suggested to function as ion channels.
Prabhat Pratap Singh Tomar   +2 more
doaj   +1 more source

Effective Control Strategy against Bacterial Blight on Carrot [PDF]

open access: yesResearch in Plant Disease, 2023
Bacterial blight of carrot caused by Xanthomonas hortorum pv. carotae (Xhc) is one of the serious diseases of carrot, of which control measures has not been still established in the domestic farm.
Hyun Su Kang   +3 more
doaj   +1 more source

Structural analysis of kasugamycin inhibition of translation [PDF]

open access: yesNature Structural & Molecular Biology, 2006
The prokaryotic ribosome is an important target of antibiotic action. We determined the X-ray structure of the aminoglycoside kasugamycin (Ksg) in complex with the Escherichia coli 70S ribosome at 3.5-A resolution. The structure reveals that the drug binds within the messenger RNA channel of the 30S subunit between the universally conserved G926 and ...
Barbara S, Schuwirth   +6 more
openaire   +2 more sources

Kasugamycin and Validamycin differentially inhibit housefly larval growth through gut microbiota regulation

open access: yesEcotoxicology and Environmental Safety
Certain bactericides exhibit dual efficacy in suppressing phytopathogens and managing insect pests. The houseflies may ingest organic matter containing bactericide residues, thereby facilitate the bioaccumulation of toxic compounds within ecosystems ...
Xinxin Kong   +7 more
doaj   +1 more source

Biochar and Cd Alter the Degradation and Transport of Kasugamycin in Soil and Spinach

open access: yesAgriculture, 2023
Biochar has been widely studied to reduce multiple contaminant sources in one matrix (e.g., several heavy metals in soils), yet less attention has been paid to accelerating pesticide degradation while in the presence of any heavy metals, such as when ...
Liqiang Cui   +5 more
doaj   +1 more source

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