Results 41 to 50 of about 3,044 (233)
Significance Several antibiotics targeting the large ribosomal subunit interfere with translation in a context-specific manner, preventing ribosomes from polymerizing specific amino acid sequences. Here, we reveal kasugamycin as a small ribosomal subunit-
Yan Zhang +6 more
semanticscholar +1 more source
Nowadays, Xanthomonas arboricola species comprises nine pathovars, two of which affect nut crops: pv. juglandis and pv. corylina. They constitute the most serious threats for walnut and hazelnut, respectively. Abstract Background The species Xanthomonas arboricola comprises up to nine pathovars, two of which affect nut crops: pv.
Monika Kałużna +6 more
wiley +1 more source
Impact of Soil Disinfestation on Fungal and Bacterial Communities in Soil With Cucumber Cultivation
Soil treatment with disinfectants has been used for controlling soilborne phytopathogens. Besides suppressing specific pathogens, how these disinfectants impact soil health, especially soil microbial communities, is yet to be systemically determined. The
Yan Wang +5 more
doaj +1 more source
Kasugamycin is a novel chitinase 1 inhibitor with strong antifibrotic effects on pulmonary fibrosis
Rationale Pulmonary fibrosis is a devastating lung disease with few therapeutic options. Chitinase 1 (CHIT1), an 18 glycosyl hydrolase family member, contributes to the pathogenesis of pulmonary fibrosis through regulation of Transforming Growth Factor ...
Jae-Hyun Lee +10 more
semanticscholar +1 more source
In Vitro Antibacterial Activity of Kasugamycin [PDF]
Kasugamycin is an aminoglycosidic antibiotic which was initially reported as being of potential use against Pseudomonas . Our evaluation of this antibiotic does not confirm this expectation. The median minimal inhibitory concentration (MIC) of the Pseudomonas strains tested was 250 μg/ml and ...
openaire +2 more sources
Bioassay to Study the Attachment of Xanthomonas albilineans Attachment on sugarcane leaves [PDF]
Sugarcane (interspecific hybrids of Saccharum species) is an economically important crop that provides 70% of raw table sugar production worldwide and contributes, in some countries, to bioethanol and electricity production.
Daugrois, Jean-Heinrich +2 more
core +1 more source
Blockers of the SARS-CoV-2 3a Channel Identified by Targeted Drug Repurposing
The etiological agent of the COVID-19 pandemic is SARS-CoV-2. As a member of the Coronaviridae, the enveloped pathogen has several membrane proteins, of which two, E and 3a, were suggested to function as ion channels.
Prabhat Pratap Singh Tomar +2 more
doaj +1 more source
Effective Control Strategy against Bacterial Blight on Carrot [PDF]
Bacterial blight of carrot caused by Xanthomonas hortorum pv. carotae (Xhc) is one of the serious diseases of carrot, of which control measures has not been still established in the domestic farm.
Hyun Su Kang +3 more
doaj +1 more source
Characterization and validation of Entamoeba histolytica pantothenate kinase as a novel anti-amebic drug target [PDF]
The Coenzyme A (CoA), as a cofactor involved in >100 metabolic reactions, is essential to the basic biochemistry of life. Here, we investigated the CoA biosynthetic pathway of Entamoeba histolytica (E.
Hashimoto Tetsuo +11 more
core +2 more sources
Operon mRNAs are organized into ORF-centric structures that predict translation efficiency [PDF]
Bacterial mRNAs are organized into operons consisting of discrete open reading frames (ORFs) in a single polycistronic mRNA. Individual ORFs on the mRNA are differentially translated, with rates varying as much as 100-fold.
Adhin +49 more
core +2 more sources

