Results 41 to 50 of about 3,044 (233)

The context of the ribosome binding site in mRNAs defines specificity of action of kasugamycin, an inhibitor of translation initiation

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2022
Significance Several antibiotics targeting the large ribosomal subunit interfere with translation in a context-specific manner, preventing ribosomes from polymerizing specific amino acid sequences. Here, we reveal kasugamycin as a small ribosomal subunit-
Yan Zhang   +6 more
semanticscholar   +1 more source

Xanthomonas arboricola pv. juglandis and pv. corylina: Brothers or distant relatives? Genetic clues, epidemiology, and insights for disease management

open access: yesMolecular Plant Pathology, Volume 22, Issue 12, Page 1481-1499, December 2021., 2021
Nowadays, Xanthomonas arboricola species comprises nine pathovars, two of which affect nut crops: pv. juglandis and pv. corylina. They constitute the most serious threats for walnut and hazelnut, respectively. Abstract Background The species Xanthomonas arboricola comprises up to nine pathovars, two of which affect nut crops: pv.
Monika Kałużna   +6 more
wiley   +1 more source

Impact of Soil Disinfestation on Fungal and Bacterial Communities in Soil With Cucumber Cultivation

open access: yesFrontiers in Microbiology, 2021
Soil treatment with disinfectants has been used for controlling soilborne phytopathogens. Besides suppressing specific pathogens, how these disinfectants impact soil health, especially soil microbial communities, is yet to be systemically determined. The
Yan Wang   +5 more
doaj   +1 more source

Kasugamycin is a novel chitinase 1 inhibitor with strong antifibrotic effects on pulmonary fibrosis

open access: yesbioRxiv, 2021
Rationale Pulmonary fibrosis is a devastating lung disease with few therapeutic options. Chitinase 1 (CHIT1), an 18 glycosyl hydrolase family member, contributes to the pathogenesis of pulmonary fibrosis through regulation of Transforming Growth Factor ...
Jae-Hyun Lee   +10 more
semanticscholar   +1 more source

In Vitro Antibacterial Activity of Kasugamycin [PDF]

open access: yesApplied Microbiology, 1967
Kasugamycin is an aminoglycosidic antibiotic which was initially reported as being of potential use against Pseudomonas . Our evaluation of this antibiotic does not confirm this expectation. The median minimal inhibitory concentration (MIC) of the Pseudomonas strains tested was 250 μg/ml and ...
openaire   +2 more sources

Bioassay to Study the Attachment of Xanthomonas albilineans Attachment on sugarcane leaves [PDF]

open access: yes, 2017
Sugarcane (interspecific hybrids of Saccharum species) is an economically important crop that provides 70% of raw table sugar production worldwide and contributes, in some countries, to bioethanol and electricity production.
Daugrois, Jean-Heinrich   +2 more
core   +1 more source

Blockers of the SARS-CoV-2 3a Channel Identified by Targeted Drug Repurposing

open access: yesViruses, 2021
The etiological agent of the COVID-19 pandemic is SARS-CoV-2. As a member of the Coronaviridae, the enveloped pathogen has several membrane proteins, of which two, E and 3a, were suggested to function as ion channels.
Prabhat Pratap Singh Tomar   +2 more
doaj   +1 more source

Effective Control Strategy against Bacterial Blight on Carrot [PDF]

open access: yesResearch in Plant Disease, 2023
Bacterial blight of carrot caused by Xanthomonas hortorum pv. carotae (Xhc) is one of the serious diseases of carrot, of which control measures has not been still established in the domestic farm.
Hyun Su Kang   +3 more
doaj   +1 more source

Characterization and validation of Entamoeba histolytica pantothenate kinase as a novel anti-amebic drug target [PDF]

open access: yes, 2018
The Coenzyme A (CoA), as a cofactor involved in >100 metabolic reactions, is essential to the basic biochemistry of life. Here, we investigated the CoA biosynthetic pathway of Entamoeba histolytica (E.
Hashimoto Tetsuo   +11 more
core   +2 more sources

Operon mRNAs are organized into ORF-centric structures that predict translation efficiency [PDF]

open access: yes, 2017
Bacterial mRNAs are organized into operons consisting of discrete open reading frames (ORFs) in a single polycistronic mRNA. Individual ORFs on the mRNA are differentially translated, with rates varying as much as 100-fold.
Adhin   +49 more
core   +2 more sources

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