Results 1 to 10 of about 76 (70)

Case Report: Progressive disease of BRCA2-mutant colon adenocarcinoma following talazoparib therapy [PDF]

Frontiers in Oncology, 2023
Colorectal cancer (CRC) is currently one of the most common tumor types diagnosed worldwide. In the early stages, the disease responds well to surgical and chemotherapeutic treatment, but in the later stages when therapeutic options are exhausted ...
Elizaveta Polyanskaya, Alexandra Lebedeva, Olesya Kuznetsova, Olesya Kuznetsova, Ekaterina Belova, Ekaterina Belova, Alexandra Kavun, Maxim Ivanov, Maxim Ivanov, Mikhail Fedyanin, Mikhail Fedyanin, Mikhail Fedyanin, Alexey Tryakin, Vladislav Mileyko, Dmitry Nosov   +14 more
doaj   +2 more sources

Acceptorless cross-dehydrogenative coupling for C(sp3)-H heteroarylation mediated by a heterogeneous GaN/ketone photocatalyst/photosensitizer system [PDF]

Communications Chemistry, 2023
Alkanes are naturally abundant chemical building blocks that contain plentiful C(sp 3)-H bonds. While inert, the activation of C(sp 3)-H via hydrogen atom abstraction (HAT) stages an appealing approach to generate alkyl radicals.
Hyotaik Kang, Lida Tan, Jing-Tan Han, Chia-Yu Huang, Hui Su, Aleksei Kavun, Chao-Jun Li   +6 more
doaj   +2 more sources

Dynamics of blood microsatellite instability (bMSI) burden predicts outcome of a patient treated with immune checkpoint inhibitors: a case report of hyperprogressive disease [PDF]

Frontiers in Immunology
Microsatellite instability (MSI) is a widely studied molecular signature, which is associated with long-term benefit in patients treated with immune checkpoint inhibitor therapy.
Daria Kravchuk, Alexandra Lebedeva, Alexandra Lebedeva, Olesya Kuznetsova, Olesya Kuznetsova, Alexandra Kavun, Anastasiia Taraskina, Ekaterina Belova, Ekaterina Belova, Ekaterina Belova, Tatiana Grigoreva, Tatiana Grigoreva, Egor Veselovsky, Vladislav Mileyko, Vladislav Mileyko, Vladislav Nikulin, Lidia Nekrasova, Alexey Tryakin, Mikhail Fedyanin, Mikhail Fedyanin, Mikhail Fedyanin, Maxim Ivanov, Maxim Ivanov   +22 more
doaj   +2 more sources

Evidence blocks for effective presentation of genomic findings at molecular tumor boards: Single institution experience [PDF]

Heliyon
Genomic profiling, or molecular profiling of the tumor, is becoming a key component of therapeutic decision making in clinical oncology, and is typically carried out via next generation sequencing.
Alexandra Lebedeva, Olesya Kuznetsova, Maxim Ivanov, Alexandra Kavun, Egor Veselovsky, Ekaterina Belova, Vladislav Mileyko, Valentina Yakushina, Polina Shilo, Alexey Tryakin, Alexey Rumyantsev, Fedor Moiseenko, Mikhail Fedyanin, Dmitry Nosov   +13 more
doaj   +2 more sources

Evaluation of blood MSI burden dynamics to trace immune checkpoint inhibitor therapy efficacy through the course of treatment [PDF]

Scientific Reports
Analysis of serial liquid biopsy (LB) samples has been found to be a promising approach for the monitoring of tumor dynamics in the course of therapy for patients with colorectal cancer (CRC).
Egor Veselovsky, Alexandra Lebedeva, Olesya Kuznetsova, Daria Kravchuk, Ekaterina Belova, Anastasia Taraskina, Tatiana Grigoreva, Alexandra Kavun, Victoria Yudina, Laima Belyaeva, Vladislav Nikulin, Vladislav Mileyko, Alexey Tryakin, Mikhail Fedyanin, Maxim Ivanov   +14 more
doaj   +2 more sources

Mitochondria-Targeted Hydrogen Sulphide Delivery via an Adhesive Hydrogel Modulates Inflammation and Oxidative Stress in Diabetic Wounds [PDF]

Gels
Chronic diabetic wounds are challenging to treat due to persistent inflammation, oxidative stress, impaired angiogenesis, and dysregulated matrix remodelling.
Mandeep Kaur Marwah, Hala Shokr, Yukta Sameer Hindalekar, Mohamad Anas Al Tahan, Karan Rana, Lissette Sanchez-Aranguren, Maymunah Sarr, Jacob Baxandall, Katy Mcgonigal, Bahareh Hassanzadeh, Shakil Ahmad, Sami A. Al-Ani, Jeevan Singh Lall, Harmony C. K. Cheema, Kavun Dhesi, Keqing Wang, Irundika H. K. Dias, Srikanth Bellary, Anisa Mahomed   +18 more
doaj   +2 more sources

Academic Performance in Different Learning Formats: Contribution of Procrastination and Coping Strategies [PDF]

ARPHA Proceedings, 2022
The purpose of this research was to study the effect on academic performance of changing the learning format and the contribution of procrastination and coping strategies to the academic performance of students, when changing the learning format from ...
LiudmilaV. Kavun, AnastasiaV. Varnavskaya   +1 more
doaj   +3 more sources

Structural and Regional Peculiarities of Developing Retail Trade in Ukraine [PDF]

Problemi Ekonomiki, 2020
The purpose of the article is to identify the structural and regional peculiarities of developing retail trade in Ukraine during 1990–2019. On the basis of the research the author has come to conclusion that the process of developing retail trade in ...
Kavun-Moshkovska Olha O.
doaj   +1 more source

Flow Feature in Supersonic Non-Isobaric Jet near the Nozzle Edge

Aerospace, 2022
Using the example of studying the supersonic underexpanded jet initial section, the issue of interpreting the experimental visualization data and Pitot pressure measurement data using the results of numerical calculations (2d RANS k-ω SST) is discussed ...
Valeriy Zapryagaev, Ivan Kavun, Nikolay Kiselev   +2 more
doaj   +1 more source

THE RELATIONSHIP OF LIFE-MEANING ORIENTATIONS AND EMOTIONAL STATE IN MEN AND WOMEN DURING THE PERIOD OF ADAPTATION TO PARENTHOOD

Russian Journal of Education and Psychology, 2022
The relevance of the study is due to an increase in the number of emotional and affective disorders in young parents during the period of adaptation to parenthood.
Sofya K. Efremova, Lyudmila V. Kavun
doaj   +1 more source