Results 11 to 20 of about 1,439 (157)

Analytical and Clinical Validation of Solo‐Test Driver: A Targeted Amplicon‐Based NGS Test‐System for FFPE and cfDNA Analysis in Clinical Oncology Setting [PDF]

Journal of Clinical Laboratory Analysis, Volume 39, Issue 6, March 2025.
With the growing demand for compact next‐generation sequencing (NGS) test systems tailored to meet key needs in oncology, the Solo‐test Driver panel serves as a valuable tool for companion diagnostics of solid tumors, demonstrating high reliability, sensitivity, and specificity in line with established guidelines. In this work, we outline the framework
Maxim Ivanov, Alexandra Lebedeva, Ekaterina Belova, Tatiana Grigoreva, Egor Veselovsky, Alexandra Kavun, Anastasiia Taraskina, Olesya Kuznetsova, Vladislav Nikulin, Laima Belyaeva, Daria Kravchuk, Tatyana Lisitsa, Alexey Barinov, Natalia Pospekhova, Saida Aliyarova, Ekaterina Khomenko, Alexey Tryakin, Irina Demidova, Anna Stroganova, Mikhail Fedyanin, Vladislav Mileyko   +20 more
wiley   +2 more sources

Case Report: Progressive disease of BRCA2-mutant colon adenocarcinoma following talazoparib therapy [PDF]

Frontiers in Oncology, 2023
Colorectal cancer (CRC) is currently one of the most common tumor types diagnosed worldwide. In the early stages, the disease responds well to surgical and chemotherapeutic treatment, but in the later stages when therapeutic options are exhausted ...
Elizaveta Polyanskaya, Alexandra Lebedeva, Olesya Kuznetsova, Olesya Kuznetsova, Ekaterina Belova, Ekaterina Belova, Alexandra Kavun, Maxim Ivanov, Maxim Ivanov, Mikhail Fedyanin, Mikhail Fedyanin, Mikhail Fedyanin, Alexey Tryakin, Vladislav Mileyko, Dmitry Nosov   +14 more
doaj   +2 more sources

A bond valence sum method to identify potential new fluoride ion conductors [PDF]

Journal of Applied Crystallography, Volume 58, Issue 6, Page 2134-2143, December 2025.
A simple modification to the bond valence site energy method is proposed to account for the asymmetrical coordination around post‐transition metal cations in fluoride conductors due to the presence of electron lone pairs. A total of 136 structures from the Inorganic Crystal Structure Database are screened and several potential new conductors are ...
Robbie Shaw, Gabriel E. Pérez, Helen Playford, Stephen Hull   +3 more
wiley   +2 more sources

Acceptorless cross-dehydrogenative coupling for C(sp3)-H heteroarylation mediated by a heterogeneous GaN/ketone photocatalyst/photosensitizer system [PDF]

Communications Chemistry, 2023
Alkanes are naturally abundant chemical building blocks that contain plentiful C(sp 3)-H bonds. While inert, the activation of C(sp 3)-H via hydrogen atom abstraction (HAT) stages an appealing approach to generate alkyl radicals.
Hyotaik Kang, Lida Tan, Jing-Tan Han, Chia-Yu Huang, Hui Su, Aleksei Kavun, Chao-Jun Li   +6 more
doaj   +2 more sources

Influence of siderite aggregate substitution on chloride resistance, durability, and gamma-ray shielding of heavy concrete [PDF]

Scientific Reports
This study investigates the effect of replacing natural aggregates with siderite (10%, 20%, 30%, and 100%) in heavyweight concretes designed for radiation shielding.
Mustafa Eken, Ayşenur Gürgen, Yusuf Kavun   +2 more
doaj   +2 more sources

Dynamics of blood microsatellite instability (bMSI) burden predicts outcome of a patient treated with immune checkpoint inhibitors: a case report of hyperprogressive disease [PDF]

Frontiers in Immunology
Microsatellite instability (MSI) is a widely studied molecular signature, which is associated with long-term benefit in patients treated with immune checkpoint inhibitor therapy.
Daria Kravchuk, Alexandra Lebedeva, Alexandra Lebedeva, Olesya Kuznetsova, Olesya Kuznetsova, Alexandra Kavun, Anastasiia Taraskina, Ekaterina Belova, Ekaterina Belova, Ekaterina Belova, Tatiana Grigoreva, Tatiana Grigoreva, Egor Veselovsky, Vladislav Mileyko, Vladislav Mileyko, Vladislav Nikulin, Lidia Nekrasova, Alexey Tryakin, Mikhail Fedyanin, Mikhail Fedyanin, Mikhail Fedyanin, Maxim Ivanov, Maxim Ivanov   +22 more
doaj   +2 more sources

Evidence blocks for effective presentation of genomic findings at molecular tumor boards: Single institution experience [PDF]

Heliyon
Genomic profiling, or molecular profiling of the tumor, is becoming a key component of therapeutic decision making in clinical oncology, and is typically carried out via next generation sequencing.
Alexandra Lebedeva, Olesya Kuznetsova, Maxim Ivanov, Alexandra Kavun, Egor Veselovsky, Ekaterina Belova, Vladislav Mileyko, Valentina Yakushina, Polina Shilo, Alexey Tryakin, Alexey Rumyantsev, Fedor Moiseenko, Mikhail Fedyanin, Dmitry Nosov   +13 more
doaj   +2 more sources

Evaluation of blood MSI burden dynamics to trace immune checkpoint inhibitor therapy efficacy through the course of treatment [PDF]

Scientific Reports
Analysis of serial liquid biopsy (LB) samples has been found to be a promising approach for the monitoring of tumor dynamics in the course of therapy for patients with colorectal cancer (CRC).
Egor Veselovsky, Alexandra Lebedeva, Olesya Kuznetsova, Daria Kravchuk, Ekaterina Belova, Anastasia Taraskina, Tatiana Grigoreva, Alexandra Kavun, Victoria Yudina, Laima Belyaeva, Vladislav Nikulin, Vladislav Mileyko, Alexey Tryakin, Mikhail Fedyanin, Maxim Ivanov   +14 more
doaj   +2 more sources

Mitochondria-Targeted Hydrogen Sulphide Delivery via an Adhesive Hydrogel Modulates Inflammation and Oxidative Stress in Diabetic Wounds [PDF]

Gels
Chronic diabetic wounds are challenging to treat due to persistent inflammation, oxidative stress, impaired angiogenesis, and dysregulated matrix remodelling.
Mandeep Kaur Marwah, Hala Shokr, Yukta Sameer Hindalekar, Mohamad Anas Al Tahan, Karan Rana, Lissette Sanchez-Aranguren, Maymunah Sarr, Jacob Baxandall, Katy Mcgonigal, Bahareh Hassanzadeh, Shakil Ahmad, Sami A. Al-Ani, Jeevan Singh Lall, Harmony C. K. Cheema, Kavun Dhesi, Keqing Wang, Irundika H. K. Dias, Srikanth Bellary, Anisa Mahomed   +18 more
doaj   +2 more sources

Diyarbakır`da yetiştirilen bazı yerli kavun genotiplerinin karakterizasyonu [PDF]

, 2015
83
Bahçivancı, Naciye
openaire   +3 more sources