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Kawasaki disease is an acute febrile, systemic vasculitic syndrome of an unknown etiology that primarily occurs in children younger than five years of age.
Abe+126 more
core +7 more sources
Kawasaki disease (KD) is an acute-onset systemic vasculitis of medium-sized vessels that mostly affects infants and toddlers. Globally, it is the most common form of childhood primary vasculitis. Delayed diagnosis and treatment results in coronary artery aneurysms in up to 25% of all affected individuals.
Hedrich, Christian M+2 more
core +5 more sources
Kawasaki disease is an acute, self-limited vasculitis of unknown etiology that occurs predominantly in infants and children. If not treated early with high-dose intravenous immunoglobulin, 1 in 5 children develop coronary artery aneurysms; this risk is reduced 5-fold if intravenous immunoglobulin is administered within 10 days of fever onset.
Newburger, Jane W+2 more
openaire +5 more sources
Kawasaki disease or Kawasaki syndrome? [PDF]
In the first months of COVID-19 pandemic, paediatricians were not much involved in the management of the illness. Reports from China had shown that relatively few children and adolescents were affected, and that most of those who were infected had experienced milder disease compared with adults.1 2 The same trend was initially seen after the spread of ...
Ravelli A.+3 more
openaire +3 more sources
Come together over me: Cells that form the dermatocranium and chondrocranium in mice
Abstract Most bone develops either by intramembranous ossification where bone forms within a soft connective tissue, or by endochondral ossification by way of a cartilage anlagen or model. Bones of the skull can form endochondrally or intramembranously or represent a combination of the two types of ossification.
M. Kathleen Pitirri+5 more
wiley +1 more source
Embryonic cranial cartilage defects in the Fgfr3Y367C/+ mouse model of achondroplasia
Abstract Achondroplasia, the most common chondrodysplasia in humans, is caused by one of two gain of function mutations localized in the transmembrane domain of fibroblast growth factor receptor 3 (FGFR3) leading to constitutive activation of FGFR3 and subsequent growth plate cartilage and bone defects.
Susan M. Motch Perrine+9 more
wiley +1 more source
Kawasaki disease is an acute vasculitis of young children that is complicated by the development of myocarditis and coronary artery abnormalities. Recent studies indicate that the prevalence of cardiovascular abnormalities can be significantly reduced by treating patients during the first 10 days of illness with high-dose intravenous gammaglobulin ...
R, Sundel, D Y, Leung
openaire +4 more sources
Kawasaki disease is an acute self-limited vasculitis of infancy and early hildhood that is now the leading cause of acquired heart disease in children in the United States and Japan. An infectious cause is suspected, although the etiology remains unknown.
Rajat Kumar Singh, Sadhna Saraf
openaire +5 more sources
Weak error analysis for a nonlinear SPDE approximation of the Dean-Kawasaki equation [PDF]
We consider a nonlinear SPDE approximation of the Dean-Kawasaki equation for independent particles. Our approximation satisfies the physical constraints of the particle system, i.e. its solution is a probability measure for all times (preservation of positivity and mass conservation).
arxiv +1 more source
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode+16 more
wiley +1 more source