APP modulates KCC2 expression and function in hippocampal GABAergic inhibition
eLife, 2017 Amyloid precursor protein (APP) is enriched at the synapse, but its synaptic function is still poorly understood. We previously showed that GABAergic short-term plasticity is impaired in App knock-out (App-/-) animals, but the precise mechanism by which ...
Ming Chen +15 more
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Differential distribution of the KCl cotransporter KCC2 in thalamic relay and reticular nuclei [PDF]
, 2004 Péter Barthó +3 more
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Brain‐type creatine kinase activates neuron‐specific K+‐Cl– co‐transporter KCC2 [PDF]
, 2005 Kōichi Inoue +3 more
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Pathophysiological role of extrasynaptic GABAA receptors in typical absence epilepsy [PDF]
, 2011 GABA is the principal inhibitory neurotransmitter in the mammalian CNS. It acts via two classes of receptors, the GABAA, a ligand gated ion channel (ionotropic receptor) and the metabotropic G-protein coupled GABAB receptor.
Crunelli, Vincenzo +2 more
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KCC2 expression in immature rat cortical neurons is sufficient to switch the polarity of GABA responses [PDF]
, 2005 Hanmi Lee +4 more
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Small-molecule screen identifies inhibitors of the neuronal K-Cl cotransporter KCC2 [PDF]
, 2009 Eric Delpire +6 more
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A Single Seizure Episode Leads to Rapid Functional Activation of KCC2 in the Neonatal Rat Hippocampus [PDF]
, 2010 Stanislav Khirug +5 more
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A gerincvelő felületes hátsó szarvi neuronhálózatok szerveződése és plaszticitása krónikus gyulladásos és neuropátiás fájdalomban = Organization and plasticity of neural microcircuits in the superficial spinal dorsal horn in chronic inflammatory and neuropathic pain [PDF]
, 2012 A kutatási terv fő célkitűzéseinek megfelelően tanulmányoztuk a nociceptiv szenzoros ingerület feldolgozás elsődleges központjának, a gerincvelő felületes hátsó szarvi neuronhálózatnak a molekuláris és celluláris szerveződését.
Antal, Miklós +6 more
core
Premature expression of KCC2 in embryonic mice perturbs neural development by an ion transport‐independent mechanism [PDF]
, 2010 Zachi Horn +4 more
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