Results 91 to 100 of about 13,280 (203)
ABSTRACT Background Melasma is a common hyperpigmentation disorder primarily affecting women, influenced by ultraviolet exposure, hormones, and genetics. Kligman's formula is a first‐line therapy, but emerging evidence suggests that topical metformin, an antidiabetic with antimelanogenic effects, may enhance treatment outcomes.
Fariba Iraji +4 more
wiley +1 more source
Background Keloids most commonly develop in the regions where the skin is constantly stretched. Although some keloid‐derived fibroblasts exhibit higher single calcium spikes than normal dermal fibroblasts during short‐time cyclical stretching, the ...
Kazuhide Mineda +11 more
doaj +1 more source
This work sought to clarify the molecular processes through which asiaticoside operates in treating keloid by utilizing an integrated approach employing scRNA-seq and systems pharmacological methods.
Xiaobo Zhou +6 more
doaj +1 more source
Methylation of LINE-1 and Alu repetitive sequence in keloid
Keloid is a trauma-induced fibroproliferative condition characterized by excessive extracellular matrix (ECM) deposition and aberrant keloid fibroblast activation, leading to physical, psychological, functional, and cosmetic impairments.
Piyawan Prabsattru +4 more
doaj +1 more source
There is sufficient evidence indicating that keloid is strongly associated with atopic dermatitis (AD) across ethnic groups. However, the molecular mechanism underlying the association is not fully understood.
Bin Zhou +17 more
doaj +1 more source
Pathological dermal scars such as keloids present significant clinical challenges lacking effective treatment options. Given the distinctive feature of highly stiffened scar tissues, deciphering how matrix mechanics regulate pathological progression can ...
Xiangting Fu +7 more
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Mendelian randomization analysis of the causal relationship between immune cells and keloid
Immune cells play complex roles in the formation of keloid. We aimed to investigate the causal relationship between immune cells and keloid and provide genetic evidence for the association between immune cells and keloid risk. Based on data from GWAS, we
Jingwen Zou, Pengkhun Nov, Kunpeng Du
doaj
Journal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
Selda Yıldırım Gençtürk +1 more
wiley +1 more source

