Results 91 to 100 of about 13,280 (203)

Correction: Advances in surface modifications of the silicone breast implant and impact on its biocompatibility and biointegration

open access: yesBiomaterials Research, 2023
Fatemeh Tavakoli Foroushani   +5 more
doaj   +1 more source

Comparison of the Efficacy of Kligman's Formula Combined With 30% Topical Metformin Versus Kligman's Formula Alone in the Treatment of Melasma

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
ABSTRACT Background Melasma is a common hyperpigmentation disorder primarily affecting women, influenced by ultraviolet exposure, hormones, and genetics. Kligman's formula is a first‐line therapy, but emerging evidence suggests that topical metformin, an antidiabetic with antimelanogenic effects, may enhance treatment outcomes.
Fariba Iraji   +4 more
wiley   +1 more source

Specific Calcium Signal Responses in Human Keloid‐Derived Fibroblasts During Cyclical Stretching: Basic Research

open access: yesHealth Science Reports
Background Keloids most commonly develop in the regions where the skin is constantly stretched. Although some keloid‐derived fibroblasts exhibit higher single calcium spikes than normal dermal fibroblasts during short‐time cyclical stretching, the ...
Kazuhide Mineda   +11 more
doaj   +1 more source

Mechanisms of asiaticoside in keloid treatment: Insights from a single-cell transcriptomic approach combined with network pharmacological analysis

open access: yesAlexandria Engineering Journal
This work sought to clarify the molecular processes through which asiaticoside operates in treating keloid by utilizing an integrated approach employing scRNA-seq and systems pharmacological methods.
Xiaobo Zhou   +6 more
doaj   +1 more source

Methylation of LINE-1 and Alu repetitive sequence in keloid

open access: yesScientific Reports
Keloid is a trauma-induced fibroproliferative condition characterized by excessive extracellular matrix (ECM) deposition and aberrant keloid fibroblast activation, leading to physical, psychological, functional, and cosmetic impairments.
Piyawan Prabsattru   +4 more
doaj   +1 more source

Identification and validation of CCR5 linking keloid with atopic dermatitis through comprehensive bioinformatics analysis and machine learning

open access: yesFrontiers in Immunology
There is sufficient evidence indicating that keloid is strongly associated with atopic dermatitis (AD) across ethnic groups. However, the molecular mechanism underlying the association is not fully understood.
Bin Zhou   +17 more
doaj   +1 more source

Targeting Nuclear Mechanics Mitigates the Fibroblast Invasiveness in Pathological Dermal Scars Induced by Matrix Stiffening

open access: yesAdvanced Science
Pathological dermal scars such as keloids present significant clinical challenges lacking effective treatment options. Given the distinctive feature of highly stiffened scar tissues, deciphering how matrix mechanics regulate pathological progression can ...
Xiangting Fu   +7 more
doaj   +1 more source

Mendelian randomization analysis of the causal relationship between immune cells and keloid

open access: yesDermatology Reports
Immune cells play complex roles in the formation of keloid. We aimed to investigate the causal relationship between immune cells and keloid and provide genetic evidence for the association between immune cells and keloid risk. Based on data from GWAS, we
Jingwen Zou, Pengkhun Nov, Kunpeng Du
doaj  

Treatment of Keloid With Fractional Microneedling Radiofrequency and Intralesional Steroid Combination

open access: yes
Journal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
Selda Yıldırım Gençtürk   +1 more
wiley   +1 more source

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