Results 111 to 120 of about 17,734 (244)
Ear Piercing Complications: Comparing Cartilage and Soft Tissue Piercings in a Large Survey Cohort
Cartilage ear piercings were associated with significantly higher complication rates than lobule piercings and remained an independent predictor of complications after multivariate analysis. Cartilage site also independently predicted piercing removal, with higher removal rates observed compared to lobule piercings.
John P. Ziegler +6 more
wiley +1 more source
Multi-omics analyses reveal bacteria and catalase associated with keloid diseaseResearch in context
Summary: Background: The pathology of keloid and especially the roles of bacteria on it were not well understood. Methods: In this study, multi-omics analyses including microbiome, metaproteomics, metabolomic, single-cell transcriptome and cell-derived ...
Mengjie Shan +22 more
doaj +1 more source
PDE4 Inhibition in Dermatologic Disease: Impacts Beyond Inflammation
This graphical abstract demonstrates the comprehensive mechanism of PDE4 inhibition in skin physiology. By increasing intracellular cAMP and activating PKA, PDE4 inhibitors exert pleiotropic effects, including immune modulation, pigmentation regulation, barrier enhancement, sensory neuron modulation, and improved wound healing with reduced fibrosis ...
Keana Khodadad +2 more
wiley +1 more source
A Case of Multiple Spontaneous Keloid Scars
Keloid scars result from an abnormal healing response to cutaneous injury or inflammation that extends beyond the borders of the original wound. Spontaneous keloid scars forming in the absence of any previous trauma or surgical procedure are rare ...
Eman Karkashan +2 more
core +1 more source
Multiorgan fibrosis arises when chronic injury activates fibroblasts and remodels extracellular matrix, whose increasing stiffness sustains disease through mechanotransduction pathways. Bidirectional cellular‐matrix feedback operates across lung, heart, liver, and kidney.
Amedeo Lonardo, Ralf Weiskirchen
wiley +1 more source
The keloid lesion is recognised as a spatially heterogeneous mass both in cellular and acellular composition and biological activity. Here, we have utilised a bioinformatic approach to determine whether this spatial heterogeneity is also evident at the ...
Taylor, Adam +23 more
core +2 more sources
ABSTRACT Background Diabetic foot ulcers (DFUs) have become an important cause of disability and death in patients with diabetes. Traditional therapies are prone to problems such as recurrence and drug resistance, which result in unsatisfactory healing effects for DFUs.
Yiran Wang +4 more
wiley +1 more source
Dose modeling of superficial brachytherapy applicator geometries using multiple radioisotopes
Abstract Background Superficial brachytherapy enables localized dose delivery for superficial cutaneous lesions, but conventional applicators may be limited in treating extended, irregular, or curved surfaces. Geometric constraints, gaps or overlaps between adjacent applicators, and placement‐related uncertainties can reduce dose uniformity ...
Jin Jegal +5 more
wiley +1 more source
Abstract Acquired lipodystrophy in the dermal white adipose tissue (DWAT) is an early phenotype of skin fibrosis, followed by the accumulation of extracellular matrix (ECM). Lipodystrophy syndromes are estimated to affect 1 in 20,000 people and are associated with metabolic comorbidities.
Suneeti R Madhavan +10 more
wiley +1 more source

