Results 131 to 140 of about 18,369 (261)
Demographic data for keloid patients and control subjects.
Demographic data for keloid patients and control subjects.
Ardeshir Bayat (182387) +2 more
core +1 more source
The Underexplored Mechanobiology of Lamin A Biogenesis and Homeostasis
We highlight current evidence, unresolved questions, and future directions, proposing that mechanical regulation of lamin A biogenesis represents an underexplored dimension of lamin mechanobiology with broad implications for development, aging, laminopathies, and mechanically driven diseases. ABSTRACT Lamin A is a major contributor to nuclear mechanics
Sandrine Fraboulet +2 more
wiley +1 more source
mRNA Therapeutics for Skin Rejuvenation: From Aging Atlases to Clinical Translation
ABSTRACT Skin aging is a multifactorial process characterized by the progressive decline of tissue structure, function and regenerative capacity. Although numerous interventions have been developed to improve the clinical manifestations of aging, most primarily alleviate downstream consequences rather than directly targeting the molecular mechanisms ...
Fabiana Boncimino +3 more
wiley +1 more source
Association between keloid and mental disorders: perspective from genetic evidence
Background The causal relationship between keloid and mental disorders remains unclear. The aim of this study was to investigate whether keloid was causally associated with the risk of bipolar disorder (BD), anxiety, schizophrenia (SCZ), major depressive
Ying Zhan +4 more
doaj +1 more source
Correlation between Adiponectin and High-Density Lipoprotein Levels and Keloid
Background: Keloid is a pathological skin condition characterized by excessive proliferation of scar tissue following injury. Although the pathophysiological mechanisms of keloid are not yet fully understood, molecular factors such as adiponectin and ...
S, Ella Finarsih E
core
PDE4 Inhibition in Dermatologic Disease: Impacts Beyond Inflammation
This graphical abstract demonstrates the comprehensive mechanism of PDE4 inhibition in skin physiology. By increasing intracellular cAMP and activating PKA, PDE4 inhibitors exert pleiotropic effects, including immune modulation, pigmentation regulation, barrier enhancement, sensory neuron modulation, and improved wound healing with reduced fibrosis ...
Keana Khodadad +2 more
wiley +1 more source
New approach to the understanding of keloid: psychoneuroimmune–endocrine aspects
Bernardo Hochman†, Felipe Contoli Isoldi, Fabianne Furtado, Lydia Masako Ferreira Plastic Surgery Division, Federal University of São Paulo, São Paulo, Brazil †Bernardo Hochman passed away on April 21, 2014 Abstract: The ...
Hochman B +3 more
core
ABSTRACT Introduction Intradermal botulinum toxin type A (BoNT‐A; microtoxin) has been shown to improve skin texture, superficial rhytides, and sweat/sebaceous activity through neuronal (cholinergic) and non‐neuronal pathways. While discussions around immune system interactions for BoNT‐A in aesthetic indications exist for intramuscular injection, the ...
Je‐Young Park +6 more
wiley +1 more source
Pathological dermal scars such as keloids present significant clinical challenges lacking effective treatment options. Given the distinctive feature of highly stiffened scar tissues, deciphering how matrix mechanics regulate pathological progression can ...
Xiangting Fu +7 more
doaj +1 more source

