Results 61 to 70 of about 22,847 (241)

3D keloid spheroid model: Development and application for personalized drug response prediction

Communications Biology
Research on keloid is limited by the lack of proper in vitro and animal model reflecting in vivo status. Based on heterogeneity of keloid and important role of endothelial cells in its pathogenesis, a novel 3D in vitro keloid spheroid prepared with ...
YoungHwan Choi, Hyung-Suk Jang, Joonho Shim, Eunhye Yeo, Min-Hee Kim, Hyungrye Noh, Sejin Oh, Ji-Hye Park, Dongyoun Lee, Jong Hee Lee   +9 more
doaj   +1 more source

Fractional CO2 Laser Combined With Topical Corticosteroids for Vulvar Lichen Simplex Chronicus: An Observational Study From an 8‐Year Single‐Center Experience

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Background Vulvar lichen simplex chronicus (VLSC) is a chronic inflammatory dermatosis that remains difficult to manage long term. Fractional CO2 laser (FxCO2) combined with topical corticosteroids (TCs) has emerged as a potential therapeutic strategy; however, high‐quality long‐term evidence remains limited.
Dongmei Wei, Jian Meng, Yanjun Zhu, Qiao Li, Yajing Wang, Yueyue Chen, Xiaoyu Niu   +6 more
wiley   +1 more source

Novel treatment approaches for keloids and hypertrophic scars in skin of colour. [PDF]

J Eur Acad Dermatol Venereol
Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 3, Page 535-536, March 2026.
Lee AD, Jeong S, Kim R, Yee KAR, Park M, Geng RSQ, Sibbald C, Bobotsis R.   +7 more
europepmc   +2 more sources

Increased epidermal thickness and abnormal epidermal differentiation in keloid scars [PDF]

, 2016
Background: The pathogenesis underlying keloid formation is still poorly understood. Research has focused mostly on dermal abnormalities, while the epidermis has not yet been studied.
Everts, V, Gibbs, S, Limandjaja, GC, Monstrey, Stan, Niessen, FB, Scheper, RJ, van den Broek, L, van Veen, HA, Waaijman, T   +8 more
core   +3 more sources

Clinical and Histopathological Assessment of the Field of Cancerization in Human Skin Before and After Treatment With a 1927‐nm Thulium Fractional Laser

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Background Field cancerization is a major concern in photodamaged skin due to its risk of progression to squamous cell carcinoma. The 1927‐nm thulium laser has emerged as a promising therapy, but its isolated effects on this condition remain underexplored.
Livia Maria Oliveira Salviano, André Bubna Hirayama, Marcella Soares Pincelli, Vivian Nunes Arruda, Rodrigo Cesar Davanço, Luiza Reis Pinto, Luis Antonio Ribeiro Torezan   +6 more
wiley   +1 more source

IL-17 Induces Autophagy Dysfunction to Promote Inflammatory Cell Death and Fibrosis in Keloid Fibroblasts via the STAT3 and HIF-1α Dependent Signaling Pathways

Frontiers in Immunology, 2022
Keloid is an abnormal fibrotic disease after cutaneous injury characterized by exaggerated scar tissue formation, which often extends beyond the boundaries of the original wound.
Seon-Yeong Lee, A Ram Lee, A Ram Lee, Jeong Won Choi, Chae Rim Lee, Chae Rim Lee, Keun-Hyung Cho, Keun-Hyung Cho, Jung Ho Lee, Mi-La Cho, Mi-La Cho   +10 more
doaj   +1 more source

In vivo terahertz imaging to evaluate scar treatment strategies : silicone gel sheeting [PDF]

, 2019
Silicone gel sheeting (SGS) is widely used for scar treatment; however, studies showing its interaction with skin and efficacy of scar treatment are still lacking.
Ahuja, Anil T., Chiu, Tor-Wo, Pickwell-MacPherson, Emma, Stantchev, Rayko I., Sun, Qiushuo, Wang, Jiarui   +5 more
core   +1 more source

Radiotherapy and Immune System Interactions Historical Perspectives and Clinical Advancements

Molecular Carcinogenesis, EarlyView.
ABSTRACT Radiotherapy (RT) has evolved significantly since its inception from treating benign conditions to becoming a cornerstone of cancer treatment. This review examines the complex interactions between RT and the immune system, highlighting its diverse effects on various immune cell populations, and exploring emerging strategies to enhance ...
Safiy Yahia, Ayman J. Oweida, Houda Bahig, Daniel Taussky   +3 more
wiley   +1 more source

Bridging Psychological Stress and Skin Cellular Aging: Flavonoids as a Dual‐Action Therapeutic Strategy

Phytotherapy Research, EarlyView.
ABSTRACT Psychological stress (or simply “stress”) is a major contributor to chronic disease worldwide, affecting 35% of the global population, including younger generations. Furthermore, it plays a significant role in human premature aging; hence, its detrimental effects on people's health compel us to comprehend and control the ways in which ...
Marco Duarte, Sílvia Santos Pedrosa, P. Raaj Khusial, Ana Raquel Madureira   +3 more
wiley   +1 more source

Предпосылки к совершенствованию фармакопрофилактики гипертрофических и келоидных рубцов [PDF]

, 2012
Проведен обзор литературы в отношении келоидных рубцов, обсуждаются направления совершенствования их лечения и ...
Жидкова, Ю. Ю., Пеньевская, Н. А., Степанова, Э. Ф.   +2 more
core   +1 more source