Results 51 to 60 of about 13,280 (203)
Small leucine‐rich proteoglycans (SLRPs) are key modulators of extracellular matrix structure and signaling. Their proteolytic processing by MMPs (Matrix Metalloproteinases), ADAMTS (disintegrin and metalloprotease with thrombospondin motifs), and serine proteases generates bioactive fragments that regulate collagen remodeling, inflammation, and ...
Maria Konstantaraki +4 more
wiley +1 more source
Emerging Deep Cutaneous Fungal Infection Caused by Cyphellophora Species in a Diabetic Patient
The Kaohsiung Journal of Medical Sciences, EarlyView.
Yi‐Shan Teng +2 more
wiley +1 more source
PDE4 Inhibition in Dermatologic Disease: Impacts Beyond Inflammation
This graphical abstract demonstrates the comprehensive mechanism of PDE4 inhibition in skin physiology. By increasing intracellular cAMP and activating PKA, PDE4 inhibitors exert pleiotropic effects, including immune modulation, pigmentation regulation, barrier enhancement, sensory neuron modulation, and improved wound healing with reduced fibrosis ...
Keana Khodadad +2 more
wiley +1 more source
Keloid is a skin lesion caused by an abnormal proliferation of fibroblasts and the deposition of collagen in the wound healing process. Therapy for keloids is relatively limited and mostly has side effects.
Mae Sri Hartati Wahyuningsih +3 more
doaj +1 more source
Several treatments are used, but the evidence base is lacking The reparative response of a fetus to injury is regeneration of tissue without scar. However, in children and adults the inevitable response to injury is scar formation, which in skin causes disfigurement and may result in restriction of motion.
openaire +2 more sources
Hyaluronic acid: A novel approach in regenerative/reconstructive periodontal therapy?
Abstract Background Although hyaluronic acid (HA) has long been used for many medical applications, only in recent years has it gained greater popularity in the field of periodontics because of its biological effects during wound healing. Even today, most clinicians are not aware that more than one type of HA exists and that the extent of its ...
Andrea Pilloni +7 more
wiley +1 more source
USP37-stabilized SALL4 promotes the keloid formation by PI3K/AKT pathway
Spalt-like transcription factor 4 (SALL4) plays a vital role in the progression of many human diseases. However, the role and mechanism of SALL4 regulates in keloid formation remain unclear.
Shuo Fang +6 more
doaj +1 more source
Diagnosis and Treatment of Keloid: Method Summary and Effect Evaluation
Yu Liu, Xiaoliang Xiong, Nan Cao, Yinlong Zhao Nuclear Medicine Department, Jilin University Second Hospital, Changchun, Jilin Province, People’s Republic of ChinaCorrespondence: Yinlong Zhao, Email yinlong@jlu.edu.cnAbstract: Keloid is a prevalent skin ...
Liu Y, Xiong X, Cao N, Zhao Y
doaj
Understanding exosomes in facial esthetics and skin aging
Abstract Background Skin aging is a multifactorial process mediated by intrinsic (genetic and metabolic) and extrinsic (environmental) factors leading to functional and structural deterioration, including wrinkles, loss of collagen and elastin, as well as various pigmentation disorders.
Richard J. Miron +3 more
wiley +1 more source

