Results 31 to 40 of about 13,280 (203)

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

Ferrostatin-1 inhibits fibroblast fibrosis in keloid by inhibiting ferroptosis [PDF]

PeerJ
Background Keloid is a chronic proliferative fibrotic disease caused by abnormal fibroblasts proliferation and excessive extracellular matrix (ECM) production.
Liu Yang, Xiuli Li, Yanli Wang
doaj   +2 more sources

Quality of life in black African patients with keloid scars

Dermatology Reports, 2020
A keloid scar is a benign skin tumor and we aimed to assess the Quality of Life (QoL) of black Africans with keloid scars based on the Dermatology Life Quality Index (DLQI).
Komenan Kassi, Kanga Kouame, Alexandre Kouassi, Ange Allou, Isidore Kouassi, Sarah Kourouma, Elidje Ecra, Abdoulaye Sangare   +7 more
doaj   +1 more source

Single-cell RNA-seq reveals the communications between extracellular matrix-related components and Schwann cells contributing to the earlobe keloid formation

Frontiers in Medicine, 2022
Keloid is a major type of skin fibrotic disease, with one prominent feature of extensive accumulation of extracellular matrix (ECM) components, and another feature of pain/itching, which is closely related to the peripheral nervous system (PNS). However,
Taogen Gong, Taogen Gong, Yayu Wang, Shaowei Dong, Xiaoshi Ma, Danfeng Du, Chang Zou, Qijun Zheng, Zhong Wen   +8 more
doaj   +1 more source

A Role for Neuregulin-1 in Promoting Keloid Fibroblast Migration via ErbB2-mediated Signaling

Acta Dermato-Venereologica, 2017
Keloid disease is a fibroproliferative tumour characterised by aggressive local invasion, evident from a clinically and histologically active migrating margin.
Natalie Jumper, Tom Hodgkinson, Ralf Paus, Ardeshir Bayat   +3 more
doaj   +1 more source

IL-13RA2 downregulation in fibroblasts promotes keloid fibrosis via JAK/STAT6 activation

JCI Insight, 2023
Keloids are considered the manifestation of a fibroproliferative disease characterized by chronic inflammation that is induced following skin injury. Deciphering the underlying mechanism of keloid formation is essential for improving treatment outcomes ...
Hua Chao, Lisheng Zheng, Pojui Hsu, Jinyun He, Ridong Wu, Shuqia Xu, Ruixi Zeng, Yuan Zhou, Huisi Ma, Haibo Liu, Qing Tang   +10 more
doaj   +1 more source

Ear Piercing Complications: Comparing Cartilage and Soft Tissue Piercings in a Large Survey Cohort

The Laryngoscope, EarlyView.
Cartilage ear piercings were associated with significantly higher complication rates than lobule piercings and remained an independent predictor of complications after multivariate analysis. Cartilage site also independently predicted piercing removal, with higher removal rates observed compared to lobule piercings.
John P. Ziegler, Nitin A. Pagedar, McKay Moline, Kathryn Marcus, Zachary G. Tanenbaum, Henry T. Hoffman, Scott R. Owen   +6 more
wiley   +1 more source

3D keloid spheroid model: Development and application for personalized drug response prediction

Communications Biology
Research on keloid is limited by the lack of proper in vitro and animal model reflecting in vivo status. Based on heterogeneity of keloid and important role of endothelial cells in its pathogenesis, a novel 3D in vitro keloid spheroid prepared with ...
YoungHwan Choi, Hyung-Suk Jang, Joonho Shim, Eunhye Yeo, Min-Hee Kim, Hyungrye Noh, Sejin Oh, Ji-Hye Park, Dongyoun Lee, Jong Hee Lee   +9 more
doaj   +1 more source

A Randomized Single‐Center Proof of Principle Study to Evaluate the Effectiveness and Safety of a Hydrogel Laser Treatment Patch in Laser Hair Removal

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Background Laser hair removal (LHR) is a commonly performed aesthetic procedure known to generate a hazardous laser plume composed of toxic chemicals, ultrafine particles, and potentially infectious biological materials. Current mitigation strategies, such as smoke evacuation systems, are costly and often used inconsistently, highlighting the ...
Barry E. DiBernardo, Gabriella A. DiBernardo, Jason N. Pozner   +2 more
wiley   +1 more source

Research progress in the pathogenesis of keloids

Pifu-xingbing zhenliaoxue zazhi, 2023
During the process of skin wound healing, hyperproliferation of fibroblasts and excessive deposition of collagen in the extracellular matrix lead to the formation of keloid, a benign tumor with characteristics of aggressive growth.
Kunpeng JIA, Jing ZHOU
doaj   +1 more source