An abnormality in glucocorticoid receptor expression differentiates steroid responders from nonresponders in keloid disease [PDF]
, 2015 Background: Glucocorticoids (GCs) are first-line treatment for keloid disease (KD) but are limited by high incidence of resistance, recurrence and undesirable sideeffects. Identifying patient responsiveness early could guide therapy.
Bayat, A +6 more
core +1 more source
Axillary Keloid Formation after Osmidrosis Surgery [PDF]
Archives of Aesthetic Plastic Surgery, 2013 Keloid is a scar tissue that undergoes recovery and excessive growth over the original wounds when the collagen is excessively accumulated in the dermis during the wound healing process.
So-Min Hwang +4 more
doaj +1 more source
Elastic fiber assembly is disrupted by excessive accumulation of chondroitin sulfate in the human dermal fibrotic disease, keloid [PDF]
, 2009 Keloid is a fibrotic disease characterized by abnormal accumulation of extracellular matrix in the dermis. The keloid matrix contains excess collagen and glycosaminoglycans (GAGs), but lacks elastic fiber. However, the roles of these matrix components in
Ikeda, Mika +10 more
core +1 more source
5-Fluorouracil in the Treatment of Keloids and Hypertrophic Scars: A Comprehensive Review of the Literature [PDF]
, 2016 Hypertrophic (HTSs) and keloid scars are common dermatological complaints produced by disruption of the normal wound-healing process. Despite a wide array of therapeutic options available to treat these lesions, HTSs and keloids continue to pose a ...
Adam S. Aldahan +5 more
core +1 more source
Heteroenxerto de quelóide na bolsa jugal do hamster (Mesocricetus auratus) [PDF]
, 2005 PURPOSE: To study the integration of keloid heterograft in hamster (Mesocricetus auratus) cheek pouch. METHODS: The sample is formed by 18 male hamsters, heterogenic ones, aged between 10 and 14 weeks.
Ferreira, Lydia Masako +3 more
core +4 more sources
Is leukotriene B4 one of the keloid marker? a fibroblast keloid study
Dermatology Reports, 2019 Keloid pathogenesis occurs due to the duration of prolonged inflammatory phase and increased production of various growth factors such as TGF-β1 which may cause increasing fibroblast proliferation and collagen synthesis.
Yuli Kurniawati +3 more
doaj +1 more source
MicroRNA-21 may be involved in the therapeutic effects of Galla chinensis ointment on keloid
Journal of International Medical Research, 2020 Objective Galla chinensis ointment can inhibit the proliferation of keloid fibroblasts and decrease keloid formation. We investigated whether Galla chinensis ointment inhibits keloid fibroblast proliferation through expression of microRNA-21 ...
Zhiming Tang +5 more
doaj +1 more source
KELOID; PRODUCTION OF KELOID ANIMAL MODEL
THE PROFESSIONAL MEDICAL JOURNAL, 2016 Keloids and hypertrophic scars are basically an overabundance of fibrosis in cutaneous healing process. Unfortunately, keloids are only found in human beings. So far no successful animal model of keloid has been reported. Objectives: To produce an animal model of keloid. Main Outcome Measure: Animal model of keloid.
Abdul Mannan Babar, Abdul Hannan Nagi
openaire +2 more sources
Frontiers in Physiology, 2017 Several studies have reported on certain aspects of the characteristics of different sites within a keloid lesion, but detailed studies on the keloid dermis at different depths within a keloid lesion are scarce.
Hu Jiao +3 more
doaj +1 more source
Increased epidermal thickness and abnormal epidermal differentiation in keloid scars [PDF]
, 2016 Background: The pathogenesis underlying keloid formation is still poorly understood. Research has focused mostly on dermal abnormalities, while the epidermis has not yet been studied.
Everts, V +8 more
core +3 more sources