Results 11 to 20 of about 18,369 (261)

Is leukotriene B4 one of the keloid marker? a fibroblast keloid study [PDF]

Dermatology Reports, 2019
Keloid pathogenesis occurs due to the duration of prolonged inflammatory phase and increased production of various growth factors such as TGF-β1 which may cause increasing fibroblast proliferation and collagen synthesis.
Yuli Kurniawati, Oki Suwarsa, A. Achadiyani, Sudigdo Adi   +3 more
doaj   +2 more sources

Debulking keloid pada telinga kiri [PDF]

Jurnal Kesehatan Andalas, 2018
Pendahuluan: Keloid adalah lesi proliferatif jinak dari jaringan konektif dermis yang biasanya dihasilkan dari respon jaringan terhadap trauma kulit pada orang-orang dengan predisposisi, dimana tidak sembuh secara spontan.
Ennesta Asri, Sri Lestari, Nadya Hasriningrum, Meligasari L Gaya   +3 more
doaj   +2 more sources

The epigenetics of keloids [PDF]

Experimental Dermatology, 2021
AbstractKeloid scarring is a fibroproliferative disorder of the skin with unknown pathophysiology, characterised by fibrotic tissue that extends beyond the boundaries of the original wound. Therapeutic options are few and commonly ineffective, with keloids very commonly recurring even after surgery and adjunct treatments.
Andrew W. Stevenson, Zhenjun Deng, Amira Allahham, Cecilia M. Prêle, Fiona M. Wood, Mark W. Fear   +5 more
openaire   +2 more sources

A Case of Keloid

Journal of Pharmacy and Bioallied Sciences, 2021
Keloids are unorganized proliferation of fibrous tissue, usually arising from a site of injury, due to an aberrant healing process. Clinically, it presents as an ugly scar tissue on the skin and shows genetic predilection. They cause esthetic, physical, and psychological disturbances in the affected individuals.
Venkataramana Vannala, Nazargi Mahabob, Senthilnathan Radhakrishnan, Sambavi Anbuselvan   +3 more
openaire   +3 more sources

DHMEQ, a novel NF-kappaB inhibitor, suppresses growth and type I collagen accumulation in keloid fibroblasts [PDF]

, 2008
Background:Keloid is a benign dermal tumor characterized by proliferation of dermal fibroblasts and overproduction of extracellular matrix (ECM). Nuclear factor kappaB (NF-κB) plays an important role in regulation of inflammation, immune response and ...
Nakashima, Masahiro, Sachio Makino, A., Saenko Vladimir, Vladimir A. Saenko, Yamashita, Shunichi, Makino, Sachio, Katsumi Tanaka, Mitsutake, Norisato, A. Saenko, Vladimir, Hirano, Akiyoshi, Kazuo Umezawa, Norisato Mitsutake, Ohtsuru, Akira, Shunichi Yamashita, Tanaka, Katsumi, Akira Ohtsuru, Masahiro Nakashima, Akiyoshi Hirano, Umezawa, Kazuo   +18 more
core   +1 more source

Botulinum Toxin A for the Treatment of Keloids [PDF]

, 2012
Introduction: Keloids are the result of excessive scar tissue formation. Besides their poor aesthetic appearance, keloids can be associated with severe clinical symptoms such as pain, itching, and rigidity.
Bureik, D., Schauber, J, Ruzicka, T, Gauglitz, Gerd, Dombrowski, Yvonne, Pavicic, T., Pavicic, T, Ruzicka, Thomas, Gauglitz, G G, Schauber, Jürgen, Dombrowski, Y; id_orcid, Bureik, D   +11 more
core   +1 more source

HtrA1 Is Specifically Up-Regulated in Active Keloid Lesions and Stimulates Keloid Development [PDF]

, 2018
Keloids occur after failure of the wound healing process; inflammation persists, and various treatments are ineffective. Keloid pathogenesis is still unclear.
Naitoh, Motoko, Toshihiro Ishiko, Tatsuki Enoshiri, Kubota, Hiroshi, Hiroshi Kubota, Taku Tamura, Mika Ikeda, Shigehiko Suzuki, Yoshikawa, Katsuhiro, Suzuki, Shigehiko, Rino Aya, Tamura, Taku, Ikeda, Mika, Yamawaki, Satoko, Enoshiri, Tatsuki, Katsuhiro Yoshikawa, Satoko Yamawaki, Katayama, Yasuhiro, Ishiko, Toshihiro, Motoko Naitoh, Yasuhiro Katayama, Aya, Rino   +21 more
core   +1 more source

Reconstructed human keloid models show heterogeneity within keloid scars [PDF]

, 2018
Keloid scars are often described as having an actively growing peripheral margin with a regressing centre. The aim of this study was to examine the possible heterogeneity within keloids and the involvement of different regions within and around keloid ...
Niessen, F.B., Waaijman, Taco, Monstrey, S., Monstrey, Stan, Limandjaja, Grace C, Gibbs, Susan, Waaijman, T., van den Broek, L.J., Limandjaja, G.C., van den Broek, Leonarda J, Breetveld, Melanie, Scheper, Rik J, Scheper, R.J., Breetveld, M., Gibbs, S., Niessen, Frank B   +15 more
core   +2 more sources

Secreted Factors from Keloid Keratinocytes Modulate Collagen Deposition by Fibroblasts from Normal and Fibrotic Tissue: A Pilot Study

Biomedicines, 2020
Interactions between keratinocytes and fibroblasts in the skin layers are crucial in normal tissue development, wound healing, and scarring. This study has investigated the role of keloid keratinocytes in regulating collagen production by primary ...
Mansour A. Alghamdi, Laith N. AL-Eitan, Andrew Stevenson, Nutan Chaudhari, Nicole Hortin, Hilary J. Wallace, Patricia L. Danielsen, Mitali Manzur, Fiona M. Wood, Mark W. Fear   +9 more
doaj   +1 more source

Axillary Keloid Formation after Osmidrosis Surgery [PDF]

Archives of Aesthetic Plastic Surgery, 2013
Keloid is a scar tissue that undergoes recovery and excessive growth over the original wounds when the collagen is excessively accumulated in the dermis during the wound healing process.
So-Min Hwang, Sang-Hwan Lee, Hyung-Do Kim, Yong-Hui Jung, Hong-il Kim   +4 more
doaj   +1 more source