Identification and histological validation of autophagy-related core genes ADRB2 and PLK2 in keloids, with integrated immune infiltration analysis [PDF]
IntroductionKeloids are pathological fibroproliferative scars characterized by excessive collagen deposition and a lack of effective targeted therapies.
Junjie Jin +7 more
doaj +2 more sources
Study on the Potential Molecular Mechanism of Keloid Disease Associated With Single Cell Combined Mendelian Randomization [PDF]
ABSTRACT Background Keloids are pathological scars with incompletely understood pathogenesis. This study aims to identify the key genes and regulatory networks potentially involved in keloid formation by integrating single‐cell transcriptomics (scRNA‐seq), protein quantitative trait loci (pQTL), Mendelian randomization (MR) analyses, colocalization ...
Hui‐Hui Wu +5 more
wiley +2 more sources
Eruptive Keloids in a Young Female Following Varicella: A Case Report [PDF]
Development of multiple eruptive keloids in a 15‐year‐old female following varicella infection, highlighting a rare temporal association and the role of inflammatory and profibrotic pathways in aberrant wound healing. ABSTRACT Keloids are fibroproliferative scars extending beyond the original wound margin and are more common in individuals with darker ...
Sandesh Shah +5 more
wiley +2 more sources
Corrigendum to ‘Superior Antiproliferative and Enhanced Synergistic Effects of a Rock Inhibitor in Multiple Models for Keloid Disease’ JID Innovations, Volume 5, Issue 6, November 2025, 100402 [PDF]
Zeinab Ghasemishahrestani +3 more
doaj +2 more sources
Skin Cell Proliferation Stimulated by Microneedles [PDF]
A classical wound may be defined as a disruption of tissue integrity. Wounds, caused by trauma from accidents or surgery, that close via secondary intention rely on the biological phases of healing, i.e., hemostasis, inflammation, proliferation, and ...
Kloth, Luther C., Liebl, Horst
core +2 more sources
Partial epithelial-mesenchymal transition in keloid scars: regulation of keloid keratinocyte gene expression by transforming growth factor-β1 [PDF]
Dorothy M Supp
exaly +2 more sources
Expression of fibroblast-activation protein in keloid tissue and its clinical significance
Objective: To investigate the expression of fibroblast-activation protein(FAP) in keloid tissue and its role in the development of keloid. Methods: Immunochemical staining was used to evaluate the expression of FAP in 30 cases of keloid tissue (case ...
Yu-xiong ZOU, Ming-chun CHEN, Li-da XU
doaj +1 more source
Turner syndrome and associated problems in turkish children: A multicenter study [PDF]
Objective: Turner syndrome (TS) is a chromosomal disorder caused by complete or partial X chromosome monosomy that manifests various clinical features depending on the karyotype and on the genetic background of affected girls.
Abacı, A. +73 more
core +1 more source
Sister Mary Joseph's Nodule at a University Teaching Hospital in Northwestern Tanzania: A Retrospective Review of 34 cases. [PDF]
Sister Mary Joseph's nodule is a metastatic tumor deposit in the umbilicus and often represents advanced intra-abdominal malignancy with dismal prognosis. There is a paucity of published data on this subject in our setting.
A Dubreuil +35 more
core +1 more source
Interactions between keratinocytes and fibroblasts in the skin layers are crucial in normal tissue development, wound healing, and scarring. This study has investigated the role of keloid keratinocytes in regulating collagen production by primary ...
Mansour A. Alghamdi +9 more
doaj +1 more source

