Results 11 to 20 of about 17,734 (244)

The Superficial Dermis May Initiate Keloid Formation: Histological Analysis of the Keloid Dermis at Different Depths

open access: yesFrontiers in Physiology, 2017
Several studies have reported on certain aspects of the characteristics of different sites within a keloid lesion, but detailed studies on the keloid dermis at different depths within a keloid lesion are scarce.
Jincai Fan, Ran Xiao, Tiran Zhang
exaly   +4 more sources

Debulking keloid pada telinga kiri [PDF]

open access: yesJurnal Kesehatan Andalas, 2018
Pendahuluan: Keloid adalah lesi proliferatif jinak dari jaringan konektif dermis yang biasanya dihasilkan dari respon jaringan terhadap trauma kulit pada orang-orang dengan predisposisi, dimana tidak sembuh secara spontan.
Ennesta Asri   +3 more
doaj   +2 more sources

The Keloid Disorder: Heterogeneity, Histopathology, Mechanisms and Models

open access: yesFrontiers in Cell and Developmental Biology, 2020
Keloids constitute an abnormal fibroproliferative wound healing response in which raised scar tissue grows excessively and invasively beyond the original wound borders.
Grace Limandjaja   +2 more
exaly   +3 more sources

Decoding the cGAS–STING–eosinophils predictive and natural therapeutic molecular signature in burn injury progression and keloid formation: insights from artificial intelligence-driven multiomics [PDF]

open access: yesFrontiers in Surgery
BackgroundInflammation-related pathway activation contributes to the progression of burn injury and keloid formation.ObjectiveOur study aimed to investigate the role of the cGAS–STING pathway in regulating eosinophils during the progression of burn ...
Jingjing Li, Qinghua Yang
doaj   +2 more sources

Collagen promotes PD-L1 overexpression in fibroblasts through binding to CD44 and activating YAP1 signaling during keloid formation [PDF]

open access: yesScientific Reports
Keloid is a skin collagen disease secondary to skin injury, characterized by excessive collagen deposition and a markedly high rate of recurrence. To date, there is still a lack of effective prevention and treatment methods for keloid. Thus, it is urgent
Lingfeng Chen   +6 more
doaj   +2 more sources

A Holistic Approach to Unravel Keloid Pathogenesis and Optimize Therapeutic Outcomes [PDF]

open access: yesBiomedicines
Although tremendous progress has been made over the past decades in elucidating the mechanisms of keloid formation and developing therapeutic interventions, keloid remains challenging to cure and prone to recurrence.
Zhendong Cao, Wei Liu
doaj   +2 more sources

Diagnosis and Treatment of Keloid: Method Summary and Effect Evaluation

open access: yesClinical, Cosmetic and Investigational Dermatology, 2023
Yu Liu, Xiaoliang Xiong, Nan Cao, Yinlong Zhao Nuclear Medicine Department, Jilin University Second Hospital, Changchun, Jilin Province, People’s Republic of ChinaCorrespondence: Yinlong Zhao, Email yinlong@jlu.edu.cnAbstract: Keloid is a prevalent skin ...
Nan Cao
exaly   +2 more sources

The epigenetics of keloids [PDF]

open access: yesExperimental Dermatology, 2021
AbstractKeloid scarring is a fibroproliferative disorder of the skin with unknown pathophysiology, characterised by fibrotic tissue that extends beyond the boundaries of the original wound. Therapeutic options are few and commonly ineffective, with keloids very commonly recurring even after surgery and adjunct treatments.
Andrew W. Stevenson   +5 more
openaire   +2 more sources

6: Biomimetic Microtissue Keloid Scar System Using Keloid-derived Fibroblasts and Macrophages

open access: yesPlastic and Reconstructive Surgery, Global Open, 2021
Purpose: Keloid is a disease that affects millions of patients and has relatively few effective treatment options. Unfortunately, traditional 2D monolayer culture of keloid derived fibroblasts show little resemblance to the pathological process in vivo ...
Yu Tan, Ph.D   +4 more
doaj   +1 more source

Advances in surface modifications of the silicone breast implant and impact on its biocompatibility and biointegration

open access: yesBiomaterials Research, 2022
Silicone breast implants are commonly used for cosmetic and oncologic surgical indications owing to their inertness and being nontoxic. However, complications including capsular contracture and anaplastic large cell lymphoma have been associated with ...
Fatemeh Tavakoli Foroushani   +5 more
doaj   +1 more source

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